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Q9C774

- PSD7B_ARATH

UniProt

Q9C774 - PSD7B_ARATH

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Protein
26S proteasome non-ATPase regulatory subunit 7 homolog B
Gene
RPN8B, MEE34, At3g11270, F11B9.19
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins By similarity.

GO - Biological processi

  1. embryo development ending in seed dormancy Source: TAIR
  2. protein catabolic process Source: TAIR
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_106068. Autodegradation of Cdh1 by Cdh1:APC/C.
REACT_107429. Orc1 removal from chromatin.
REACT_185297. Separation of Sister Chromatids.
REACT_187712. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_187719. ER-Phagosome pathway.
REACT_187848. Antigen processing: Ubiquitination & Proteasome degradation.
REACT_190947. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_94347. APC/C:Cdc20 mediated degradation of Securin.

Protein family/group databases

MEROPSiM67.973.

Names & Taxonomyi

Protein namesi
Recommended name:
26S proteasome non-ATPase regulatory subunit 7 homolog B
Alternative name(s):
26S proteasome regulatory subunit RPN8b
Short name:
AtRPN8b
Protein MATERNAL EFFECT EMBRYO ARREST 34
Gene namesi
Name:RPN8B
Synonyms:MEE34
Ordered Locus Names:At3g11270
ORF Names:F11B9.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 3

Organism-specific databases

TAIRiAT3G11270.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: TAIR
  2. proteasome complex Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Proteasome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 31031026S proteasome non-ATPase regulatory subunit 7 homolog B
PRO_0000423178Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine1 Publication

Keywords - PTMi

Acetylation

Proteomic databases

PRIDEiQ9C774.

Expressioni

Gene expression databases

ArrayExpressiQ9C774.
GenevestigatoriQ9C774.

Interactioni

Subunit structurei

Component of the 19S regulatory particule (RP/PA700) lid subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.2 Publications

Protein-protein interaction databases

IntActiQ9C774. 15 interactions.
STRINGi3702.AT3G11270.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ9C774.
SMRiQ9C774. Positions 14-292.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 123110MPN
Add
BLAST

Sequence similaritiesi

Belongs to the peptidase M67A family.

Phylogenomic databases

HOGENOMiHOG000209236.
InParanoidiQ9C774.
KOiK03038.
OMAiINAKEHI.
PhylomeDBiQ9C774.

Family and domain databases

InterProiIPR000555. JAMM/MPN+_dom.
IPR024969. Rpn11/EIF3F_C.
[Graphical view]
PfamiPF01398. JAB. 1 hit.
PF13012. MitMem_reg. 1 hit.
[Graphical view]
SMARTiSM00232. JAB_MPN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. Align

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9C774-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MDVIKTQQIS ARTIEKVIVH PLVLLSIVDH YNRVAKDTSK RVVGVLLGSS    50
SRGTVDVTNS YAVPFEEDDK DTSIWFLDHN YHESMFHMFK RINAKEHIVG 100
WYSTGPKLRE NDLDVHALFN GYVPNPVLVI IDVQPKELGI PTKAYYAVEE 150
VKENATQKSQ QVFVHVPTEI AAHEVEEIGV EHLLRDVKDT TISTLATEVT 200
AKLTALKGLD ARLREIRTYL DLVIEGKLPL NHEILYHLQD VFNLLPNLNV 250
NELVKAFAVK TNDMMLVIYL SSLIRSVIAL HSLINNKLLN KEHEKAEDSK 300
PVDIPLITES 310
Length:310
Mass (Da):35,085
Last modified:June 1, 2001 - v1
Checksum:i122D45B6A9E2A7ED
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY258412 mRNA. Translation: AAP83300.1.
AC073395 Genomic DNA. Translation: AAG50979.1.
CP002686 Genomic DNA. Translation: AEE75022.1.
AK228032 mRNA. Translation: BAE99993.1.
RefSeqiNP_187736.1. NM_111962.4. [Q9C774-1]
UniGeneiAt.39785.

Genome annotation databases

EnsemblPlantsiAT3G11270.1; AT3G11270.1; AT3G11270. [Q9C774-1]
GeneIDi820298.
KEGGiath:AT3G11270.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY258412 mRNA. Translation: AAP83300.1 .
AC073395 Genomic DNA. Translation: AAG50979.1 .
CP002686 Genomic DNA. Translation: AEE75022.1 .
AK228032 mRNA. Translation: BAE99993.1 .
RefSeqi NP_187736.1. NM_111962.4. [Q9C774-1 ]
UniGenei At.39785.

3D structure databases

ProteinModelPortali Q9C774.
SMRi Q9C774. Positions 14-292.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9C774. 15 interactions.
STRINGi 3702.AT3G11270.1-P.

Protein family/group databases

MEROPSi M67.973.

Proteomic databases

PRIDEi Q9C774.

Protocols and materials databases

DNASUi 820298.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT3G11270.1 ; AT3G11270.1 ; AT3G11270 . [Q9C774-1 ]
GeneIDi 820298.
KEGGi ath:AT3G11270.

Organism-specific databases

TAIRi AT3G11270.

Phylogenomic databases

HOGENOMi HOG000209236.
InParanoidi Q9C774.
KOi K03038.
OMAi INAKEHI.
PhylomeDBi Q9C774.

Enzyme and pathway databases

Reactomei REACT_106068. Autodegradation of Cdh1 by Cdh1:APC/C.
REACT_107429. Orc1 removal from chromatin.
REACT_185297. Separation of Sister Chromatids.
REACT_187712. Cross-presentation of soluble exogenous antigens (endosomes).
REACT_187719. ER-Phagosome pathway.
REACT_187848. Antigen processing: Ubiquitination & Proteasome degradation.
REACT_190947. AUF1 (hnRNP D0) destabilizes mRNA.
REACT_94347. APC/C:Cdc20 mediated degradation of Securin.

Gene expression databases

ArrayExpressi Q9C774.
Genevestigatori Q9C774.

Family and domain databases

InterProi IPR000555. JAMM/MPN+_dom.
IPR024969. Rpn11/EIF3F_C.
[Graphical view ]
Pfami PF01398. JAB. 1 hit.
PF13012. MitMem_reg. 1 hit.
[Graphical view ]
SMARTi SM00232. JAB_MPN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Purification of the Arabidopsis 26 S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms."
    Yang P., Fu H., Walker J., Papa C.M., Smalle J., Ju Y.-M., Vierstra R.D.
    J. Biol. Chem. 279:6401-6413(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBUNIT, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: cv. Columbia.
  2. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
    Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
    , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes."
    Book A.J., Gladman N.P., Lee S.S., Scalf M., Smith L.M., Vierstra R.D.
    J. Biol. Chem. 285:25554-25569(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY, CHARACTERIZATION OF THE 26S PROTEASOME COMPLEX, SUBUNIT, ACETYLATION AT MET-1.

Entry informationi

Entry nameiPSD7B_ARATH
AccessioniPrimary (citable) accession number: Q9C774
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2013
Last sequence update: June 1, 2001
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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