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Protein

DEAD-box ATP-dependent RNA helicase 20

Gene

RH20

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing.By similarity

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi143 – 150ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
Biological processNonsense-mediated mRNA decay, Ribosome biogenesis, rRNA processing
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:AT1G35250-MONOMER
ReactomeiR-ATH-3899300 SUMOylation of transcription cofactors
R-ATH-72163 mRNA Splicing - Major Pathway

Names & Taxonomyi

Protein namesi
Recommended name:
DEAD-box ATP-dependent RNA helicase 20 (EC:3.6.4.13)
Gene namesi
Name:RH20
Ordered Locus Names:At1g55150
ORF Names:T7N22.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G55150
TAIRilocus:2035741 AT1G55150

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002391611 – 501DEAD-box ATP-dependent RNA helicase 20Add BLAST501

Proteomic databases

PaxDbiQ9C718
PRIDEiQ9C718

PTM databases

iPTMnetiQ9C718

Expressioni

Gene expression databases

ExpressionAtlasiQ9C718 baseline and differential
GenevisibleiQ9C718 AT

Interactioni

Protein-protein interaction databases

BioGridi27183, 2 interactors
STRINGi3702.AT1G55150.1

Structurei

3D structure databases

ProteinModelPortaliQ9C718
SMRiQ9C718
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini130 – 305Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST176
Domaini333 – 478Helicase C-terminalPROSITE-ProRule annotationAdd BLAST146

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi99 – 127Q motifAdd BLAST29
Motifi253 – 256DEAD box4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi483 – 486Poly-Pro4

Domaini

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0331 Eukaryota
COG0513 LUCA
HOGENOMiHOG000268804
InParanoidiQ9C718
KOiK12823
OMAiANMHNGM
OrthoDBiEOG09360A5Q
PhylomeDBiQ9C718

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequencei

Sequence statusi: Complete.

Q9C718-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRYDSRTGD STSYRDRRSD SGFGGTSSYG SSGSHTSSKK DNDGNESPRK
60 70 80 90 100
LDLDGLTPFE KNFYVESPAV AAMTDTEVEE YRKLREITVE GKDIPKPVKS
110 120 130 140 150
FRDVGFPDYV LEEVKKAGFT EPTPIQSQGW PMAMKGRDLI GIAETGSGKT
160 170 180 190 200
LSYLLPAIVH VNAQPMLAHG DGPIVLVLAP TRELAVQIQQ EASKFGSSSK
210 220 230 240 250
IKTTCIYGGV PKGPQVRDLQ KGVEIVIATP GRLIDMMESN NTNLRRVTYL
260 270 280 290 300
VLDEADRMLD MGFDPQIRKI VSHIRPDRQT LYWSATWPKE VEQLSKKFLY
310 320 330 340 350
NPYKVIIGSS DLKANRAIRQ IVDVISESQK YNKLVKLLED IMDGSRILVF
360 370 380 390 400
LDTKKGCDQI TRQLRMDGWP ALSIHGDKSQ AERDWVLSEF RSGKSPIMTA
410 420 430 440 450
TDVAARGLDV KDVKYVINYD FPGSLEDYVH RIGRTGRAGA KGTAYTFFTV
460 470 480 490 500
ANARFAKELT NILQEAGQKV SPELASMGRS TAPPPPGLGG FRDRGSRRGW

S
Length:501
Mass (Da):55,576
Last modified:June 1, 2001 - v1
Checksum:i29F6B4B874939D4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC073944 Genomic DNA Translation: AAG50841.1
CP002684 Genomic DNA Translation: AEE33192.1
AY062745 mRNA Translation: AAL32823.1
AY128786 mRNA Translation: AAM91186.1
AJ010470 mRNA Translation: CAA09209.1
PIRiB96593
T51345
RefSeqiNP_175911.1, NM_104388.4
UniGeneiAt.20425

Genome annotation databases

EnsemblPlantsiAT1G55150.1; AT1G55150.1; AT1G55150
GeneIDi841958
GrameneiAT1G55150.1; AT1G55150.1; AT1G55150
KEGGiath:AT1G55150

Similar proteinsi

Entry informationi

Entry nameiRH20_ARATH
AccessioniPrimary (citable) accession number: Q9C718
Secondary accession number(s): Q9ZS02
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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