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Protein

Putative CCR4-associated factor 1 homolog 4

Gene

CAF1-4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression (By similarity).By similarity

Catalytic activityi

Exonucleolytic cleavage of poly(A) to 5'-AMP.

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi29 – 291Divalent metal cation; catalyticBy similarity
Metal bindingi31 – 311Divalent metal cation; catalyticBy similarity
Metal bindingi145 – 1451Divalent metal cation; catalyticBy similarity
Metal bindingi218 – 2181Divalent metal cation; catalyticBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Metal-binding, RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative CCR4-associated factor 1 homolog 4 (EC:3.1.13.4)
Gene namesi
Name:CAF1-4
Ordered Locus Names:At1g27890
ORF Names:F13K9.1, F28L5.5
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G27890.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Putative CCR4-associated factor 1 homolog 4PRO_0000371554Add
BLAST

Proteomic databases

PaxDbiQ9C6M9.
PRIDEiQ9C6M9.

PTM databases

iPTMnetiQ9C6M9.

Interactioni

Subunit structurei

Component of the CCR4-NOT complex, at least composed of CRR4 and CAF1 proteins.By similarity

Protein-protein interaction databases

BioGridi24917. 1 interaction.
STRINGi3702.AT1G27890.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C6M9.
SMRiQ9C6M9. Positions 3-229.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CAF1 family.Curated

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9C6M9.
KOiK12581.
OMAiPDDLLYQ.
PhylomeDBiQ9C6M9.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9C6M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEVWRWNKE VEMDSIRDCL KHFSSIAIDT EFPGCLKETP MDASEEIRYR
60 70 80 90 100
DMKFNVDNTH LIQLGFTLFD RRGITKTWEI NLSDFNEHKC FKNDKSIAFL
110 120 130 140 150
KSNGLNLDKI GEEGIGIEEF FRDFSQILKE KDGKITWVNF QGSYDNAYLV
160 170 180 190 200
KGLTGGKPLP ETKEEFHETV EQLLGKFVFD VKKIAESCSG LSSRFGLQRI
210 220 230 240 250
ADVLQMKRVG KAHHAGSDSE LTARVFTKLT FDLLNSRKQC VRRVDHQQYQ
260 270 280 290 300
LEQQQLMMTR CYIPIPIPIP RPRSVMFAAH HPNPYFGGGY FGMPVQGRNY

VL
Length:302
Mass (Da):34,862
Last modified:June 1, 2001 - v1
Checksum:iF19BC314E98E1174
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069471 Genomic DNA. Translation: AAG51471.1.
AC079280 Genomic DNA. Translation: AAG50583.1.
CP002684 Genomic DNA. Translation: AEE30888.1.
PIRiB86404.
RefSeqiNP_174110.1. NM_102554.1.
UniGeneiAt.66896.

Genome annotation databases

EnsemblPlantsiAT1G27890.1; AT1G27890.1; AT1G27890.
GeneIDi839682.
GrameneiAT1G27890.1; AT1G27890.1; AT1G27890.
KEGGiath:AT1G27890.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC069471 Genomic DNA. Translation: AAG51471.1.
AC079280 Genomic DNA. Translation: AAG50583.1.
CP002684 Genomic DNA. Translation: AEE30888.1.
PIRiB86404.
RefSeqiNP_174110.1. NM_102554.1.
UniGeneiAt.66896.

3D structure databases

ProteinModelPortaliQ9C6M9.
SMRiQ9C6M9. Positions 3-229.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24917. 1 interaction.
STRINGi3702.AT1G27890.1.

PTM databases

iPTMnetiQ9C6M9.

Proteomic databases

PaxDbiQ9C6M9.
PRIDEiQ9C6M9.

Protocols and materials databases

DNASUi839682.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G27890.1; AT1G27890.1; AT1G27890.
GeneIDi839682.
GrameneiAT1G27890.1; AT1G27890.1; AT1G27890.
KEGGiath:AT1G27890.

Organism-specific databases

TAIRiAT1G27890.

Phylogenomic databases

eggNOGiKOG0304. Eukaryota.
COG5228. LUCA.
HOGENOMiHOG000173077.
InParanoidiQ9C6M9.
KOiK12581.
OMAiPDDLLYQ.
PhylomeDBiQ9C6M9.

Miscellaneous databases

PROiQ9C6M9.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR006941. RNase_CAF1.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF04857. CAF1. 1 hit.
[Graphical view]
SUPFAMiSSF53098. SSF53098. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiCAF1D_ARATH
AccessioniPrimary (citable) accession number: Q9C6M9
Secondary accession number(s): Q9C7G3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: June 1, 2001
Last modified: May 11, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.