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Protein

Glutathione S-transferase F14

Gene

GSTF14

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

GO - Molecular functioni

GO - Biological processi

  • glutathione metabolic process Source: GO_Central
  • toxin catabolic process Source: TAIR

Keywordsi

Molecular functionTransferase
Biological processDetoxification

Enzyme and pathway databases

BioCyciARA:AT1G49860-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase F14 (EC:2.5.1.18)
Short name:
AtGSTF14
Alternative name(s):
GST class-phi member 14
Gene namesi
Name:GSTF14
Ordered Locus Names:At1g49860
ORF Names:F10F5.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G49860
TAIRilocus:2007278 AT1G49860

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004135471 – 254Glutathione S-transferase F14Add BLAST254

Proteomic databases

PaxDbiQ9C6C8

Expressioni

Gene expression databases

ExpressionAtlasiQ9C6C8 baseline and differential
GenevisibleiQ9C6C8 AT

Interactioni

Protein-protein interaction databases

BioGridi26634, 1 interactor
IntActiQ9C6C8, 1 interactor
STRINGi3702.AT1G49860.1

Structurei

3D structure databases

ProteinModelPortaliQ9C6C8
SMRiQ9C6C8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 85GST N-terminalAdd BLAST82
Domaini92 – 231GST C-terminalAdd BLAST140

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni42 – 43Glutathione bindingBy similarity2
Regioni56 – 57Glutathione bindingBy similarity2
Regioni69 – 70Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily. Phi family.Curated

Phylogenomic databases

eggNOGiENOG410INUJ Eukaryota
ENOG41117ZS LUCA
HOGENOMiHOG000125746
InParanoidiQ9C6C8
KOiK00799
OMAiFKFPKVH
OrthoDBiEOG09360M18
PhylomeDBiQ9C6C8

Family and domain databases

CDDicd03187 GST_C_Phi, 1 hit
InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR034347 GST_Phi_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF00043 GST_C, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q9C6C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSKMKLHC GFIWGNSAAL FCINEKGLDF ELVFVDWLAG EAKTKTFLST
60 70 80 90 100
LNPFGEVPVL EDGDLKLFEP KAITRYLAEQ YKDVGTNLLP DDPKKRAIMS
110 120 130 140 150
MWMEVDSNQF LPIASTLIKE LIINPYQGLA TDDTAVQENK EKLSEVLNIY
160 170 180 190 200
ETRLGESPYL AGESFSLADL HHLAPIDYLL NTDEEELKNL IYSRPNVAAW
210 220 230 240 250
VEKMKMRPAW LKTVVMKNHI VDLMKQRRLP IKLDSSCHES TVVAQKNAIA

IENK
Length:254
Mass (Da):28,819
Last modified:June 1, 2001 - v1
Checksum:iC38D25BA560602D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079674 Genomic DNA Translation: AAG51779.1
CP002684 Genomic DNA Translation: AEE32484.1
BT010408 mRNA Translation: AAQ62409.1
AK176306 mRNA Translation: BAD44069.1
PIRiE96535
RefSeqiNP_175408.1, NM_103873.5
UniGeneiAt.38148

Genome annotation databases

EnsemblPlantsiAT1G49860.1; AT1G49860.1; AT1G49860
GeneIDi841409
GrameneiAT1G49860.1; AT1G49860.1; AT1G49860
KEGGiath:AT1G49860

Similar proteinsi

Entry informationi

Entry nameiGSTFE_ARATH
AccessioniPrimary (citable) accession number: Q9C6C8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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