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Protein

14-3-3-like protein GF14 iota

Gene

GRF12

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Is associated with a DNA binding complex that binds to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.By similarity

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-ATH-1445148. Translocation of GLUT4 to the plasma membrane.
R-ATH-3371453. Regulation of HSF1-mediated heat shock response.
R-ATH-3371511. HSF1 activation.

Names & Taxonomyi

Protein namesi
Recommended name:
14-3-3-like protein GF14 iota
Alternative name(s):
General regulatory factor 12
Gene namesi
Name:GRF12
Ordered Locus Names:At1g26480
ORF Names:T1K7.15
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G26480.
TAIRilocus:2197940. AT1G26480.

Subcellular locationi

  • Nucleus By similarity
  • Cytoplasm By similarity

  • Note: Translocates from the cytosol to the nucleus when phosphorylated.By similarity

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000586742 – 26814-3-3-like protein GF14 iotaAdd BLAST267

Proteomic databases

PaxDbiQ9C5W6.
PRIDEiQ9C5W6.

PTM databases

iPTMnetiQ9C5W6.

Expressioni

Gene expression databases

ExpressionAtlasiQ9C5W6. baseline and differential.
GenevisibleiQ9C5W6. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi24425. 6 interactors.
IntActiQ9C5W6. 1 interactor.
MINTiMINT-8059115.
STRINGi3702.AT1G26480.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C5W6.
SMRiQ9C5W6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
HOGENOMiHOG000240379.
InParanoidiQ9C5W6.
OMAiMIWEYQQ.
OrthoDBiEOG09360J6R.
PhylomeDBiQ9C5W6.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9C5W6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSGSDKER ETFVYMAKLS EQAERYDEMV ETMKKVARVN SELTVEERNL
60 70 80 90 100
LSVGYKNVIG ARRASWRIMS SIEQKEESKG NESNVKQIKG YRQKVEDELA
110 120 130 140 150
NICQDILTII DQHLIPHATS GEATVFYYKM KGDYYRYLAE FKTEQERKEA
160 170 180 190 200
AEQSLKGYEA ATQAASTELP STHPIRLGLA LNFSVFYYEI MNSPERACHL
210 220 230 240 250
AKQAFDEAIA ELDTLSEESY KDSTLIMQLL RDNLTLWTSD LPEDGGEDNI
260
KTEESKQEQA KPADATEN
Length:268
Mass (Da):30,545
Last modified:June 1, 2001 - v1
Checksum:i914F394CEC07A28C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti268N → VVIHFKMRTDQRAWKLNEI in AAF98570 (PubMed:11130712).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335544 mRNA. Translation: AAK11271.1.
AC013427 Genomic DNA. Translation: AAF98570.1.
CP002684 Genomic DNA. Translation: AEE30696.1.
BT006230 mRNA. Translation: AAP12879.1.
PIRiF86391.
RefSeqiNP_564249.1. NM_102411.3.
UniGeneiAt.15965.

Genome annotation databases

EnsemblPlantsiAT1G26480.1; AT1G26480.1; AT1G26480.
GeneIDi839189.
GrameneiAT1G26480.1; AT1G26480.1; AT1G26480.
KEGGiath:AT1G26480.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry namei14312_ARATH
AccessioniPrimary (citable) accession number: Q9C5W6
Secondary accession number(s): Q9FZD3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 5, 2001
Last sequence update: June 1, 2001
Last modified: June 7, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families