Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9C5U0

- AHK4_ARATH

UniProt

Q9C5U0 - AHK4_ARATH

Protein

Histidine kinase 4

Gene

AHK4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 95 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cytokinins (CK) receptor related to bacterial two-component regulators. Binds also the synthetic urea-type cytokinin thiadiazuron, a potent defoliant and herbicide. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.28 Publications

    Catalytic activityi

    ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Enzyme regulationi

    Activated by cytokinins to initiate phosphorelay signaling. This cytokinin-mediated activation is repressed by the trans-zeatin antagonists 6-(2-hydroxy-3-methylbenzylamino)purine (PI-55) and 6-(2,5-Dihydroxybenzylamino)purine (LGR-991).3 Publications

    pH dependencei

    Optimum pH to bind cytokinin is about 7-8.5 at 0 degrees Celsius.2 Publications

    Temperature dependencei

    Cytokinin-binding is more stable at 0 degrees Celsius than at 20 and 37 degrees Celsius.2 Publications

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei285 – 2851Cytokinin
    Binding sitei307 – 3071Cytokinin; via amide nitrogen
    Binding sitei317 – 3171Cytokinin

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. cytokine binding Source: TAIR
    3. cytokinin receptor activity Source: TAIR
    4. enzyme binding Source: UniProtKB
    5. osmosensor activity Source: TAIR
    6. phosphoprotein phosphatase activity Source: TAIR
    7. phosphorelay response regulator activity Source: InterPro
    8. phosphorelay sensor kinase activity Source: InterPro
    9. protein binding Source: UniProtKB
    10. protein histidine kinase activity Source: TAIR
    11. protein histidine kinase binding Source: UniProtKB
    12. protein kinase binding Source: UniProtKB
    13. transmembrane histidine kinase cytokinin receptor activity Source: UniProtKB

    GO - Biological processi

    1. carbohydrate homeostasis Source: TAIR
    2. cellular response to phosphate starvation Source: UniProtKB
    3. cellular response to sucrose stimulus Source: UniProtKB
    4. cytokinin-activated signaling pathway Source: TAIR
    5. defense response to bacterium Source: TAIR
    6. dephosphorylation Source: GOC
    7. embryonic root morphogenesis Source: TAIR
    8. osmosensory signaling pathway Source: TAIR
    9. peptidyl-histidine phosphorylation Source: GOC
    10. phosphorelay signal transduction system Source: UniProtKB
    11. protein phosphorylation Source: TAIR
    12. regulation of meristem development Source: UniProtKB
    13. regulation of seed germination Source: TAIR
    14. regulation of shoot system development Source: TAIR
    15. response to water deprivation Source: TAIR
    16. sulfate transport Source: UniProtKB

    Keywords - Molecular functioni

    Developmental protein, Hydrolase, Kinase, Protein phosphatase, Transferase

    Keywords - Biological processi

    Cytokinin signaling pathway

    Enzyme and pathway databases

    BioCyciARA:AT2G01830-MONOMER.
    ARA:GQT-91-MONOMER.
    ARA:GQT-92-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Histidine kinase 4 (EC:2.7.13.3)
    Alternative name(s):
    Arabidopsis histidine kinase 4
    Short name:
    AtHK4
    Cytokinin receptor CYTOKININ RESPONSE 1
    Short name:
    AtCRE1
    Short name:
    Cytokinin receptor CRE1
    Phosphoprotein phosphatase AHK4 (EC:3.1.3.16)
    Protein AUTHENTIC HIS-KINASE 4
    Protein ROOT AS IN WOL 1
    Protein WOODEN LEG
    Gene namesi
    Name:AHK4
    Synonyms:CRE1, RAW1, WOL
    Ordered Locus Names:At2g01830
    ORF Names:T23K3.2
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G01830.

    Subcellular locationi

    Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication

    GO - Cellular componenti

    1. endoplasmic reticulum Source: TAIR
    2. endoplasmic reticulum membrane Source: UniProtKB-SubCell
    3. integral component of membrane Source: UniProtKB-KW
    4. plasma membrane Source: UniProtKB

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    Pathology & Biotechi

    Disruption phenotypei

    Reduced sensitivity to cytokinin (mostly in shoots). Narrow vascular cylinder composed mainly of protoxylem cell files, with no apparent metaxylem or phloem. Hypersensitivity to ABA. Strong drought and salinity tolerance only in the presence of CK. Reduced cytokinin repression of several Pi starvation-responsive genes and increased sucrose sensitivity. More rapid germination, reduced requirement for light, and decreased far-red light sensitivity. Reduced sensitivity to N-isobutyl decanamide. Impaired benzyladenine (6-BA)-mediated repression of the iron uptake pathway. Impaired meristematic development in seedlings.12 Publications

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi225 – 2251A → L: Loss of activity. 1 Publication
    Mutagenesisi227 – 2271A → L: Loss of activity. 1 Publication
    Mutagenesisi273 – 2731Y → E: Loss of activity. 1 Publication
    Mutagenesisi279 – 2791M → A: No effect on activity. 1 Publication
    Mutagenesisi285 – 2851D → A, E or R: Loss of activity. 1 Publication
    Mutagenesisi301 – 3011T → I in wol-1; locked in the phosphoprotein phosphatase active form, retardation of the primary root growth with reduced cell number and exclusive xylem differentiation within the vascular tissue associated with abnormal vascular asymmetric cell divisions, impaired metaxylem and phloem differentiation, and reduced cytokinin-binding ability leading to impaired kinase activity and cyokinin-mediated activation. 6 Publications
    Mutagenesisi303 – 3031P → V: Loss of activity. 1 Publication
    Mutagenesisi304 – 3041F → A: Loss of activity. 1 Publication
    Mutagenesisi306 – 3061L → A: Loss of activity. 1 Publication
    Mutagenesisi307 – 3071L → A: Loss of activity. 1 Publication
    Mutagenesisi317 – 3171T → A: No effect on activity. 1 Publication
    Mutagenesisi343 – 3431G → L: Loss of activity. 1 Publication
    Mutagenesisi435 – 4351G → C: Constitutively activated independently of cytokinin. 1 Publication
    Mutagenesisi436 – 4361F → S: Constitutively activated independently of cytokinin. 1 Publication
    Mutagenesisi447 – 4471M → T: Constitutively activated independently of cytokinin. 1 Publication
    Mutagenesisi459 – 4591M → I in wol-3; retardation of the primary root growth, no production of lateral roots and enhanced formation of adventitious roots associated with impaired auxin basipetal transport. 1 Publication
    Mutagenesisi471 – 4711V → A: Constitutively activated independently of cytokinin. 1 Publication
    Mutagenesisi482 – 4821H → Q: Reduced phosphoprotein phosphatase activity. 2 Publications
    Mutagenesisi490 – 4901G → D in cre1-1; impaired histidine-kinase receptor activity and reduced responses to cytokinins, including rapid cell proliferation and shoot formation in tissue culture, repression of sulfate uptake, retardation of the primary root growth, no production of lateral roots and enhanced formation of adventitious roots associated with impaired auxin basipetal transport, as well as reduced cell number within the vascular tissues in roots. 4 Publications
    Mutagenesisi493 – 4931G → R in cre1-6; reduced sensitivity to cytokinin. 1 Publication
    Mutagenesisi494 – 4941M → L: Constitutively activated independently of cytokinin. 1 Publication
    Mutagenesisi529 – 5291L → F in wol-2/raw1; impaired metaxylem and phloem differentiation, and reduced sensitivity to cytokinins. 1 Publication
    Mutagenesisi529 – 5291L → F in wol-2; retardation of the primary root growth with reduced cell number and exclusive xylem differentiation within the vascular tissue associated with abnormal vascular asymmetric cell divisions, and impaired cytokinin-binding ability. 1 Publication
    Mutagenesisi708 – 7081F → L: No histidine kinase activity, but normal phosphoprotein phosphatase activity. 1 Publication
    Mutagenesisi996 – 9961D → N: Cytokinin-mediated autophosphorylation but impaired phosphotransfer to an HPt, abolished phosphoprotein phosphatase activity. 2 Publications
    Mutagenesisi1008 – 10081T → I in cre1-4; slightly reduced sensitivity to cytokinin, and impaired cytokinin repression of several Pi starvation-responses. 1 Publication
    Mutagenesisi1032 – 10321A → T in cre1-9; impaired cytokinin repression of several Pi starvation-responses. 1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10801080Histidine kinase 4PRO_0000398589Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei482 – 4821Phosphohistidine; by autocatalysis1 PublicationPROSITE-ProRule annotation
    Modified residuei996 – 99614-aspartylphosphatePROSITE-ProRule annotation

    Post-translational modificationi

    Autophosphorylated predominantly on His residues. Activation probably requires a transfer of a phosphate group between a His in the transmitter domain and an Asp of the receiver domain.1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PaxDbiQ9C5U0.
    PRIDEiQ9C5U0.

    Expressioni

    Tissue specificityi

    Mostly expressed in roots, specifically in the vascular cylinder and pericycle, and, to a lower extent, in leaves and flowers. Present in seedlings.4 Publications

    Developmental stagei

    Expressed specifically in the vasculature since the early stages of embryogenesis. At the globular stage of embryogenesis, detected in the four innermost cells, which are the precursors of the vascular tissue. During the heart, torpedo, and nearly mature stages, expressed in the procambium of the cotyledon shoulders, prospective hypocotyl, and embryonic root. In seedlings, mainly localized in meristematic tissues (e.g. shoot apical meristem SAM, root tips, and growing leaf and lateral root primordia), especially in vasculature. Present in all the vasculature and the shoot apical meristem (SAM) of the adult plant. In flowers, localized in carpels and developing ovules. In the root tips, expressed in the central cylinder.3 Publications

    Inductioni

    Rapidly induced by dehydration. Down-regulated by Pi starvation and induced by cytokinins.2 Publications

    Gene expression databases

    GenevestigatoriQ9C5U0.

    Interactioni

    Subunit structurei

    Homodimer. Interacts with AHP1, AHP2, AHP3, AHP5, AHK3, AMPD, FBR12, WNK5 and At4g15630.5 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    AHK3Q9C5U12EBI-1100775,EBI-1100653
    AMPDO804522EBI-1100775,EBI-1807679
    At1g03430Q67XQ13EBI-1100775,EBI-1100725
    At4g15630Q8L8Z12EBI-1100775,EBI-1807704
    WNK5Q9SCU52EBI-1100775,EBI-1807651

    Protein-protein interaction databases

    BioGridi117. 30 interactions.
    IntActiQ9C5U0. 29 interactions.
    STRINGi3702.AT2G01830.2-P.

    Structurei

    Secondary structure

    1
    1080
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi151 – 19343
    Turni194 – 1963
    Beta strandi197 – 1993
    Helixi204 – 21310
    Helixi215 – 2173
    Beta strandi221 – 2288
    Helixi232 – 2343
    Helixi235 – 2428
    Turni249 – 2513
    Beta strandi259 – 2613
    Beta strandi263 – 2675
    Helixi269 – 2746
    Helixi279 – 2813
    Helixi283 – 29513
    Turni307 – 3093
    Beta strandi312 – 32110
    Helixi331 – 3366
    Beta strandi338 – 3469
    Helixi348 – 35710
    Helixi362 – 3643
    Beta strandi365 – 3717
    Beta strandi379 – 3824
    Beta strandi385 – 3873
    Beta strandi395 – 3995
    Beta strandi408 – 4147

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3T4JX-ray1.65A/B149-418[»]
    3T4KX-ray1.77A/B149-418[»]
    3T4LX-ray1.53A/B149-418[»]
    3T4OX-ray1.75A/B149-418[»]
    3T4QX-ray2.30A/B149-418[»]
    3T4SX-ray1.60A/B149-418[»]
    3T4TX-ray1.70A/B149-418[»]
    ProteinModelPortaliQ9C5U0.
    SMRiQ9C5U0. Positions 150-416, 465-752, 941-1060.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9C5U0.

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 124124CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini146 – 429284ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini451 – 1080630CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei125 – 14521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei430 – 45021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini198 – 411214CHASEPROSITE-ProRule annotationAdd
    BLAST
    Domaini479 – 760282Histidine kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini946 – 1071126Response regulatoryPROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi823 – 8264Poly-Ala

    Sequence similaritiesi

    Contains 1 CHASE domain.PROSITE-ProRule annotation
    Contains 1 histidine kinase domain.PROSITE-ProRule annotation
    Contains 1 response regulatory domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0784.
    InParanoidiQ9C5U0.
    KOiK14489.
    OMAiNQNRPSF.
    PhylomeDBiQ9C5U0.

    Family and domain databases

    Gene3Di1.10.287.130. 1 hit.
    3.30.565.10. 2 hits.
    InterProiIPR006189. CHASE.
    IPR011006. CheY-like_superfamily.
    IPR003661. EnvZ-like_dim/P.
    IPR003594. HATPase_ATP-bd.
    IPR004358. Sig_transdc_His_kin-like_C.
    IPR005467. Sig_transdc_His_kinase_core.
    IPR009082. Sig_transdc_His_kinase_dimeric.
    IPR001789. Sig_transdc_resp-reg_receiver.
    [Graphical view]
    PfamiPF03924. CHASE. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00512. HisKA. 1 hit.
    PF00072. Response_reg. 1 hit.
    [Graphical view]
    PRINTSiPR00344. BCTRLSENSOR.
    SMARTiSM01079. CHASE. 1 hit.
    SM00387. HATPase_c. 1 hit.
    SM00388. HisKA. 1 hit.
    SM00448. REC. 1 hit.
    [Graphical view]
    SUPFAMiSSF47384. SSF47384. 1 hit.
    SSF52172. SSF52172. 2 hits.
    SSF55874. SSF55874. 2 hits.
    PROSITEiPS50839. CHASE. 1 hit.
    PS50109. HIS_KIN. 1 hit.
    PS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9C5U0-1) [UniParc]FASTAAdd to Basket

    Also known as: CRE1b

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MRRDFVYNNN AMFNPLTTHY SSDMNWALNN HQEEEEEPRR IEISDSESLE     50
    NLKSSDFYQL GGGGALNSSE KPRKIDFWRS GLMGFAKMQQ QQQLQHSVAV 100
    KMNNNNNNDL MGNKKGSTFI QEHRALLPKA LILWIIIVGF ISSGIYQWMD 150
    DANKIRREEV LVSMCDQRAR MLQDQFSVSV NHVHALAILV STFHYHKNPS 200
    AIDQETFAEY TARTAFERPL LSGVAYAEKV VNFEREMFER QHNWVIKTMD 250
    RGEPSPVRDE YAPVIFSQDS VSYLESLDMM SGEEDRENIL RARETGKAVL 300
    TSPFRLLETH HLGVVLTFPV YKSSLPENPT VEERIAATAG YLGGAFDVES 350
    LVENLLGQLA GNQAIVVHVY DITNASDPLV MYGNQDEEAD RSLSHESKLD 400
    FGDPFRKHKM ICRYHQKAPI PLNVLTTVPL FFAIGFLVGY ILYGAAMHIV 450
    KVEDDFHEMQ ELKVRAEAAD VAKSQFLATV SHEIRTPMNG ILGMLAMLLD 500
    TELSSTQRDY AQTAQVCGKA LIALINEVLD RAKIEAGKLE LESVPFDIRS 550
    ILDDVLSLFS EESRNKSIEL AVFVSDKVPE IVKGDSGRFR QIIINLVGNS 600
    VKFTEKGHIF VKVHLAEQSK DESEPKNALN GGVSEEMIVV SKQSSYNTLS 650
    GYEAADGRNS WDSFKHLVSE EQSLSEFDIS SNVRLMVSIE DTGIGIPLVA 700
    QGRVFMPFMQ ADSSTSRNYG GTGIGLSISK CLVELMRGQI NFISRPHIGS 750
    TFWFTAVLEK CDKCSAINHM KKPNVEHLPS TFKGMKAIVV DAKPVRAAVT 800
    RYHMKRLGIN VDVVTSLKTA VVAAAAFERN GSPLPTKPQL DMILVEKDSW 850
    ISTEDNDSEI RLLNSRTNGN VHHKSPKLAL FATNITNSEF DRAKSAGFAD 900
    TVIMKPLRAS MIGACLQQVL ELRKTRQQHP EGSSPATLKS LLTGKKILVV 950
    DDNIVNRRVA AGALKKFGAE VVCAESGQVA LGLLQIPHTF DACFMDIQMP 1000
    QMDGFEATRQ IRMMEKETKE KTNLEWHLPI LAMTADVIHA TYEECLKSGM 1050
    DGYVSKPFEE ENLYKSVAKS FKPNPISPSS 1080
    Length:1,080
    Mass (Da):120,731
    Last modified:June 1, 2001 - v1
    Checksum:i5950DB968B529401
    GO
    Isoform 2 (identifier: Q9C5U0-2) [UniParc]FASTAAdd to Basket

    Also known as: CRE1a

    The sequence of this isoform differs from the canonical sequence as follows:
         1-23: Missing.

    Show »
    Length:1,057
    Mass (Da):117,955
    Checksum:iE1381C8685F0D787
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti567 – 5671S → G in BAB33311. (PubMed:11234017)Curated
    Sequence conflicti1018 – 10181T → A in BAB33311. (PubMed:11234017)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti765 – 7651S → N in strain: cv. Se-0. 1 Publication

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 2323Missing in isoform 2. 3 PublicationsVSP_039770Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ278528 mRNA. Translation: CAC18521.1.
    AJ278529 mRNA. Translation: CAC18522.1.
    AJ278530 mRNA. Translation: CAC18523.1.
    AB049934 mRNA. Translation: BAB33310.1.
    AB049935 mRNA. Translation: BAB33311.1.
    AB046871 mRNA. Translation: BAB40776.1.
    AC007069 Genomic DNA. Translation: AAD21777.2.
    CP002685 Genomic DNA. Translation: AEC05505.1.
    CP002685 Genomic DNA. Translation: AEC05506.1.
    CP002685 Genomic DNA. Translation: AEC05507.1.
    EF598292 Genomic DNA. Translation: ABQ85264.1.
    EF598293 Genomic DNA. Translation: ABQ85265.1.
    EF598294 Genomic DNA. Translation: ABQ85266.1.
    EF598295 Genomic DNA. Translation: ABQ85267.1.
    EF598296 Genomic DNA. Translation: ABQ85268.1.
    EF598297 Genomic DNA. Translation: ABQ85269.1.
    EF598298 Genomic DNA. Translation: ABQ85270.1.
    EF598299 Genomic DNA. Translation: ABQ85271.1.
    EF598300 Genomic DNA. Translation: ABQ85272.1.
    EF598301 Genomic DNA. Translation: ABQ85273.1.
    EF598302 Genomic DNA. Translation: ABQ85274.1.
    EF598303 Genomic DNA. Translation: ABQ85275.1.
    EF598304 Genomic DNA. Translation: ABQ85276.1.
    EF598305 Genomic DNA. Translation: ABQ85277.1.
    EF598306 Genomic DNA. Translation: ABQ85278.1.
    EF598307 Genomic DNA. Translation: ABQ85279.1.
    EF598308 Genomic DNA. Translation: ABQ85280.1.
    EF598309 Genomic DNA. Translation: ABQ85281.1.
    EF598310 Genomic DNA. Translation: ABQ85282.1.
    EF598311 Genomic DNA. Translation: ABQ85283.1.
    EF598312 Genomic DNA. Translation: ABQ85284.1.
    EF598313 Genomic DNA. Translation: ABQ85285.1.
    EF598314 Genomic DNA. Translation: ABQ85286.1.
    EF598315 Genomic DNA. Translation: ABQ85287.1.
    PIRiF84429.
    RefSeqiNP_565277.1. NM_126244.2. [Q9C5U0-2]
    NP_849925.1. NM_179594.1. [Q9C5U0-1]
    NP_973396.1. NM_201667.1. [Q9C5U0-2]
    UniGeneiAt.10485.

    Genome annotation databases

    EnsemblPlantsiAT2G01830.2; AT2G01830.2; AT2G01830. [Q9C5U0-1]
    GeneIDi814714.
    KEGGiath:AT2G01830.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ278528 mRNA. Translation: CAC18521.1 .
    AJ278529 mRNA. Translation: CAC18522.1 .
    AJ278530 mRNA. Translation: CAC18523.1 .
    AB049934 mRNA. Translation: BAB33310.1 .
    AB049935 mRNA. Translation: BAB33311.1 .
    AB046871 mRNA. Translation: BAB40776.1 .
    AC007069 Genomic DNA. Translation: AAD21777.2 .
    CP002685 Genomic DNA. Translation: AEC05505.1 .
    CP002685 Genomic DNA. Translation: AEC05506.1 .
    CP002685 Genomic DNA. Translation: AEC05507.1 .
    EF598292 Genomic DNA. Translation: ABQ85264.1 .
    EF598293 Genomic DNA. Translation: ABQ85265.1 .
    EF598294 Genomic DNA. Translation: ABQ85266.1 .
    EF598295 Genomic DNA. Translation: ABQ85267.1 .
    EF598296 Genomic DNA. Translation: ABQ85268.1 .
    EF598297 Genomic DNA. Translation: ABQ85269.1 .
    EF598298 Genomic DNA. Translation: ABQ85270.1 .
    EF598299 Genomic DNA. Translation: ABQ85271.1 .
    EF598300 Genomic DNA. Translation: ABQ85272.1 .
    EF598301 Genomic DNA. Translation: ABQ85273.1 .
    EF598302 Genomic DNA. Translation: ABQ85274.1 .
    EF598303 Genomic DNA. Translation: ABQ85275.1 .
    EF598304 Genomic DNA. Translation: ABQ85276.1 .
    EF598305 Genomic DNA. Translation: ABQ85277.1 .
    EF598306 Genomic DNA. Translation: ABQ85278.1 .
    EF598307 Genomic DNA. Translation: ABQ85279.1 .
    EF598308 Genomic DNA. Translation: ABQ85280.1 .
    EF598309 Genomic DNA. Translation: ABQ85281.1 .
    EF598310 Genomic DNA. Translation: ABQ85282.1 .
    EF598311 Genomic DNA. Translation: ABQ85283.1 .
    EF598312 Genomic DNA. Translation: ABQ85284.1 .
    EF598313 Genomic DNA. Translation: ABQ85285.1 .
    EF598314 Genomic DNA. Translation: ABQ85286.1 .
    EF598315 Genomic DNA. Translation: ABQ85287.1 .
    PIRi F84429.
    RefSeqi NP_565277.1. NM_126244.2. [Q9C5U0-2 ]
    NP_849925.1. NM_179594.1. [Q9C5U0-1 ]
    NP_973396.1. NM_201667.1. [Q9C5U0-2 ]
    UniGenei At.10485.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3T4J X-ray 1.65 A/B 149-418 [» ]
    3T4K X-ray 1.77 A/B 149-418 [» ]
    3T4L X-ray 1.53 A/B 149-418 [» ]
    3T4O X-ray 1.75 A/B 149-418 [» ]
    3T4Q X-ray 2.30 A/B 149-418 [» ]
    3T4S X-ray 1.60 A/B 149-418 [» ]
    3T4T X-ray 1.70 A/B 149-418 [» ]
    ProteinModelPortali Q9C5U0.
    SMRi Q9C5U0. Positions 150-416, 465-752, 941-1060.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 117. 30 interactions.
    IntActi Q9C5U0. 29 interactions.
    STRINGi 3702.AT2G01830.2-P.

    Chemistry

    BindingDBi Q9C5U0.
    ChEMBLi CHEMBL6124.

    Proteomic databases

    PaxDbi Q9C5U0.
    PRIDEi Q9C5U0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G01830.2 ; AT2G01830.2 ; AT2G01830 . [Q9C5U0-1 ]
    GeneIDi 814714.
    KEGGi ath:AT2G01830.

    Organism-specific databases

    TAIRi AT2G01830.

    Phylogenomic databases

    eggNOGi COG0784.
    InParanoidi Q9C5U0.
    KOi K14489.
    OMAi NQNRPSF.
    PhylomeDBi Q9C5U0.

    Enzyme and pathway databases

    BioCyci ARA:AT2G01830-MONOMER.
    ARA:GQT-91-MONOMER.
    ARA:GQT-92-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q9C5U0.

    Gene expression databases

    Genevestigatori Q9C5U0.

    Family and domain databases

    Gene3Di 1.10.287.130. 1 hit.
    3.30.565.10. 2 hits.
    InterProi IPR006189. CHASE.
    IPR011006. CheY-like_superfamily.
    IPR003661. EnvZ-like_dim/P.
    IPR003594. HATPase_ATP-bd.
    IPR004358. Sig_transdc_His_kin-like_C.
    IPR005467. Sig_transdc_His_kinase_core.
    IPR009082. Sig_transdc_His_kinase_dimeric.
    IPR001789. Sig_transdc_resp-reg_receiver.
    [Graphical view ]
    Pfami PF03924. CHASE. 1 hit.
    PF02518. HATPase_c. 1 hit.
    PF00512. HisKA. 1 hit.
    PF00072. Response_reg. 1 hit.
    [Graphical view ]
    PRINTSi PR00344. BCTRLSENSOR.
    SMARTi SM01079. CHASE. 1 hit.
    SM00387. HATPase_c. 1 hit.
    SM00388. HisKA. 1 hit.
    SM00448. REC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47384. SSF47384. 1 hit.
    SSF52172. SSF52172. 2 hits.
    SSF55874. SSF55874. 2 hits.
    PROSITEi PS50839. CHASE. 1 hit.
    PS50109. HIS_KIN. 1 hit.
    PS50110. RESPONSE_REGULATORY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root."
      Maehoenen A.P., Bonke M., Kauppinen L., Riikonen M., Benfey P.N., Helariutta Y.
      Genes Dev. 14:2938-2943(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, FUNCTION, MUTAGENESIS OF THR-301.
      Strain: cv. Columbia.
      Tissue: Root.
    2. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, ENZYME REGULATION, MUTAGENESIS OF HIS-482; GLY-490 AND ASP-996.
      Strain: cv. Wassilewskija.
      Tissue: Seedling.
    3. "Novel family of sensor histidine kinase genes in Arabidopsis thaliana."
      Ueguchi C., Koizumi H., Suzuki T., Mizuno T.
      Plant Cell Physiol. 42:231-235(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    5. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    6. "The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping."
      Ehrenreich I.M., Stafford P.A., Purugganan M.D.
      Genetics 176:1223-1236(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 722-983, VARIANT ASN-765.
      Strain: cv. Ag-0, cv. An-1, cv. Br-0, cv. C24, cv. Ct-1, cv. Cvi-1, cv. Edi-0, cv. Ga-0, cv. Kas-2, cv. Kin-0, cv. Landsberg erecta, cv. Ll-0, cv. Lz-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Se-0, cv. Sorbo, cv. Tsu-1, cv. Van-0, cv. Wa-1 and cv. Wassilewskija.
    7. "The Arabidopsis sensor His-kinase, AHk4, can respond to cytokinins."
      Suzuki T., Miwa K., Ishikawa K., Yamada H., Aiba H., Mizuno T.
      Plant Cell Physiol. 42:107-113(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH AHP1; AHP2; AHP3 AND AHP5.
    8. "The AHK4 gene involved in the cytokinin-signaling pathway as a direct receptor molecule in Arabidopsis thaliana."
      Ueguchi C., Sato S., Kato T., Tabata S.
      Plant Cell Physiol. 42:751-755(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    9. "The Arabidopsis AHK4 histidine kinase is a cytokinin-binding receptor that transduces cytokinin signals across the membrane."
      Yamada H., Suzuki T., Terada K., Takei K., Ishikawa K., Miwa K., Yamashino T., Mizuno T.
      Plant Cell Physiol. 42:1017-1023(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, ACTIVATION BY CYTOKININS, MUTAGENESIS OF THR-301.
    10. "CREam of cytokinin signalling: receptor identified."
      Schmuelling T.
      Trends Plant Sci. 6:281-284(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVIEW.
    11. "His-Asp phosphorelay signal transduction in higher plants: receptors and response regulators for cytokinin signaling in Arabidopsis thaliana."
      Oka A., Sakai H., Iwakoshi S.
      Genes Genet. Syst. 77:383-391(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: REVIEW.
    12. "Characterization of the ARR15 and ARR16 response regulators with special reference to the cytokinin signaling pathway mediated by the AHK4 histidine kinase in roots of Arabidopsis thaliana."
      Kiba T., Yamada H., Mizuno T.
      Plant Cell Physiol. 43:1059-1066(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, MUTAGENESIS OF GLY-490.
    13. "Mutations at CRE1 impair cytokinin-induced repression of phosphate starvation responses in Arabidopsis."
      Franco-Zorrilla J.M., Martin A.C., Solano R., Rubio V., Leyva A., Paz-Ares J.
      Plant J. 32:353-360(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE, INDUCTION, MUTAGENESIS OF GLY-493; THR-1008 AND ALA-1032.
    14. "Two-component signal transduction pathways in Arabidopsis."
      Hwang I., Chen H.-C., Sheen J.
      Plant Physiol. 129:500-515(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.
    15. "Histidine kinase homologs that act as cytokinin receptors possess overlapping functions in the regulation of shoot and root growth in Arabidopsis."
      Nishimura C., Ohashi Y., Sato S., Kato T., Tabata S., Ueguchi C.
      Plant Cell 16:1365-1377(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
    16. "Two cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, differ in their ligand specificity in a bacterial assay."
      Spichal L., Rakova N.Y., Riefler M., Mizuno T., Romanov G.A., Strnad M., Schmuelling T.
      Plant Cell Physiol. 45:1299-1305(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    17. "Interallelic complementation at the Arabidopsis CRE1 locus uncovers independent pathways for the proliferation of vascular initials and canonical cytokinin signalling."
      de Leon B.G.-P., Zorrilla J.M.F., Rubio V., Dahiya P., Paz-Ares J., Leyva A.
      Plant J. 38:70-79(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, MUTAGENESIS OF THR-301 AND LEU-529.
    18. "A novel regulatory pathway of sulfate uptake in Arabidopsis roots: implication of CRE1/WOL/AHK4-mediated cytokinin-dependent regulation."
      Maruyama-Nakashita A., Nakamura Y., Yamaya T., Takahashi H.
      Plant J. 38:779-789(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, MUTAGENESIS OF GLY-490.
    19. Cited for: FUNCTION, TISSUE SPECIFICITY, DISRUPTION PHENOTYPE.
    20. "A live cell hormone-binding assay on transgenic bacteria expressing a eukaryotic receptor protein."
      Romanov G.A., Spichal L., Lomin S.N., Strnad M., Schmuelling T.
      Anal. Biochem. 347:129-134(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
    21. "Interaction between phosphate-starvation, sugar, and cytokinin signaling in Arabidopsis and the roles of cytokinin receptors CRE1/AHK4 and AHK3."
      Franco-Zorrilla J.M., Martin A.C., Leyva A., Paz-Ares J.
      Plant Physiol. 138:847-857(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    22. "Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition."
      Mok M.C., Martin R.C., Dobrev P.I., Vankova R., Ho P.S., Yonekura-Sakakibara K., Sakakibara H., Mok D.W.
      Plant Physiol. 137:1057-1066(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    23. Cited for: FUNCTION, PHOSPHORYLATION AT HIS-482, MUTAGENESIS OF THR-301; HIS-482; PHE-708 AND ASP-996, DISRUPTION PHENOTYPE, DEVELOPMENTAL STAGE.
    24. "Analysis of protein interactions within the cytokinin-signaling pathway of Arabidopsis thaliana."
      Dortay H., Mehnert N., Buerkle L., Schmuelling T., Heyl A.
      FEBS J. 273:4631-4644(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH AHP1; AHP2; AHP3; AHP5 AND AHK3.
    25. "Biochemical characteristics and ligand-binding properties of Arabidopsis cytokinin receptor AHK3 compared to CRE1/AHK4 as revealed by a direct binding assay."
      Romanov G.A., Lomin S.N., Schmuelling T.
      J. Exp. Bot. 57:4051-4058(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
    26. "Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism."
      Riefler M., Novak O., Strnad M., Schmuelling T.
      Plant Cell 18:40-54(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    27. "Cytokinin receptors are required for normal development of auxin-transporting vascular tissues in the hypocotyl but not in adventitious roots."
      Kuroha T., Ueguchi C., Sakakibara H., Satoh S.
      Plant Cell Physiol. 47:234-243(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE, MUTAGENESIS OF MET-459 AND GLY-490.
    28. "The floral volatile, methyl benzoate, from snapdragon (Antirrhinum majus) triggers phytotoxic effects in Arabidopsis thaliana."
      Horiuchi J., Badri D.V., Kimball B.A., Negre F., Dudareva N., Paschke M.W., Vivanco J.M.
      Planta 226:1-10(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    29. "Identification of amino acid substitutions that render the Arabidopsis cytokinin receptor histidine kinase AHK4 constitutively active."
      Miwa K., Ishikawa K., Terada K., Yamada H., Suzuki T., Yamashino T., Mizuno T.
      Plant Cell Physiol. 48:1809-1814(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, MUTAGENESIS OF THR-301; GLY-435; PHE-436; MET-447; VAL-471 AND MET-494.
    30. "Functional analysis of AHK1/ATHK1 and cytokinin receptor histidine kinases in response to abscisic acid, drought, and salt stress in Arabidopsis."
      Tran L.S., Urao T., Qin F., Maruyama K., Kakimoto T., Shinozaki K., Yamaguchi-Shinozaki K.
      Proc. Natl. Acad. Sci. U.S.A. 104:20623-20628(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INDUCTION, DISRUPTION PHENOTYPE.
    31. Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    32. "Mechanism-based inhibitors of cytokinin oxidase/dehydrogenase attack FAD cofactor."
      Kopecny D., Sebela M., Briozzo P., Spichal L., Houba-Herin N., Masek V., Joly N., Madzak C., Anzenbacher P., Laloue M.
      J. Mol. Biol. 380:886-899(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    33. "Toward an interaction map of the two-component signaling pathway of Arabidopsis thaliana."
      Dortay H., Gruhn N., Pfeifer A., Schwerdtner M., Schmuelling T., Heyl A.
      J. Proteome Res. 7:3649-3660(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH AHP2; AMPD; WNK5 AND AT4G15630.
    34. "The role of auxins and cytokinins in the mutualistic interaction between Arabidopsis and Piriformospora indica."
      Vadassery J., Ritter C., Venus Y., Camehl I., Varma A., Shahollari B., Novak O., Strnad M., Ludwig-Mueller J., Oelmueller R.
      Mol. Plant Microbe Interact. 21:1371-1383(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    35. "Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth-dependent pathway."
      Seguela M., Briat J.-F., Vert G., Curie C.
      Plant J. 55:289-300(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    36. "The purine derivative PI-55 blocks cytokinin action via receptor inhibition."
      Spichal L., Werner T., Popa I., Riefler M., Schmuelling T., Strnad M.
      FEBS J. 276:244-253(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, ENZYME REGULATION.
    37. "STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings."
      Skylar A., Hong F., Chory J., Weigel D., Wu X.
      Development 137:541-549(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, DISRUPTION PHENOTYPE.
    38. "Cytokinin receptor antagonists derived from 6-benzylaminopurine."
      Nisler J., Zatloukal M., Popa I., Dolezal K., Strnad M., Spichal L.
      Phytochemistry 71:823-830(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: ENZYME REGULATION.
    39. "The cytokinin receptors of Arabidopsis are located mainly to the endoplasmic reticulum."
      Wulfetange K., Lomin S.N., Romanov G.A., Stolz A., Heyl A., Schmuelling T.
      Plant Physiol. 156:1808-1818(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION.
      Strain: cv. Columbia.
    40. "The Arabidopsis eukaryotic translation initiation factor eIF5A-2 regulates root protoxylem development by modulating cytokinin signaling."
      Ren B., Chen Q., Hong S., Zhao W., Feng J., Feng H., Zuo J.
      Plant Cell 25:3841-3857(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH FBR12 AND AHP1.
    41. "Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4."
      Hothorn M., Dabi T., Chory J.
      Nat. Chem. Biol. 7:766-768(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.53 ANGSTROMS) OF 149-418 IN COMPLEX WITH CYTOKININS OR THIADIAZURON, SUBUNIT, MUTAGENESIS OF ALA-225; ALA-227; TYR-273; MET-279; ASP-285; THR-301; PRO-303; PHE-304; LEU-306; LEU-307; THR-317 AND GLY-343.

    Entry informationi

    Entry nameiAHK4_ARATH
    AccessioniPrimary (citable) accession number: Q9C5U0
    Secondary accession number(s): A5YY60
    , A5YY75, Q9C5T8, Q9C5T9, Q9FDZ3, Q9SIT0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 5, 2010
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 95 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3