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Protein

Probable protein S-acyltransferase 22

Gene

PAT22

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Palmitoyl acyltransferase.By similarity1 Publication

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei193S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.225. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein S-acyltransferase 22 (EC:2.3.1.225)
Alternative name(s):
Probable palmitoyltransferase At1g69420
Zinc finger DHHC domain-containing protein At1g69420
Gene namesi
Name:PAT22
Ordered Locus Names:At1g69420
ORF Names:F10D13.9, F23O10.1
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRilocus:2007086. AT1G69420.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 35HelicalSequence analysisAdd BLAST21
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Transmembranei215 – 235HelicalSequence analysisAdd BLAST21
Transmembranei254 – 274HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Cytoplasmic vesicle, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003635891 – 596Probable protein S-acyltransferase 22Add BLAST596

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ9C533.

PTM databases

iPTMnetiQ9C533.

Expressioni

Developmental stagei

Highly expressed during bolting.1 Publication

Gene expression databases

ExpressionAtlasiQ9C533. baseline and differential.
GenevisibleiQ9C533. AT.

Interactioni

Protein-protein interaction databases

BioGridi28495. 1 interactor.
IntActiQ9C533. 1 interactor.
STRINGi3702.AT1G69420.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C533.
SMRiQ9C533.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini163 – 213DHHCPROSITE-ProRule annotationAdd BLAST51

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi555 – 560Poly-Gln6
Compositional biasi563 – 566Poly-Met4

Domaini

The DHHC domain is required for palmitoyltransferase activity.By similarity

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
HOGENOMiHOG000242421.
InParanoidiQ9C533.
KOiK20027.
OMAiIIVVATC.
OrthoDBiEOG0936090U.
PhylomeDBiQ9C533.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
PROSITEiView protein in PROSITE
PS50216. DHHC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9C533-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKHGWQLPY HPLQVVAVAV FLALGFAFYV FFAPFVGKKI HQYIAMGIYT
60 70 80 90 100
PLITCVVGLY IWCAASDPAD RGVFRSKKYL KIPENGKFPL AKDIKDGCGS
110 120 130 140 150
ATGGAKSHDG TCVEDTENGS NKKLESSERS SLLRLLCSPC ALLCSCCSGK
160 170 180 190 200
DESSEQMSED GMFYCSLCEV EVFKYSKHCR VCDKCVDRFD HHCRWLNNCI
210 220 230 240 250
GKRNYRKFFS LMVSAIFLLI MQWSTGIFVL VLCLLRRNQF NADIALKLGS
260 270 280 290 300
SFSLIPFVIV VGVCTVLAML ATLPLAQLFF FHILLIKKGI STYDYIVALR
310 320 330 340 350
EQEQELEAGG GQQSPQMSMI SSFTGLSSAS SFNTFHRGAW CTPPRLFLED
360 370 380 390 400
QFDVVPPENA SVSSYGKKSV VEERVKKKPQ PVKISPWTLA RLNAEEVSKA
410 420 430 440 450
AAEARKKSKI IQPVARRENP FVGLEASSSF GSSGRRMFPT KYEGVNNNGK
460 470 480 490 500
QRRQSKRIRL PAELPLEPLM NVQTKAAMET STSSGLAPLQ LEARSAFQTS
510 520 530 540 550
RAMSGSGNVM VTSSPESSLD SHDIHPFRVS SEAEDAAQLN GFSSAVGLMG
560 570 580 590
QQRGQQQQQQ LSMMMMPLSR STSDGYDASG GEDSDQVPSR NIHKSR
Length:596
Mass (Da):65,890
Last modified:February 10, 2009 - v2
Checksum:i3F7BF5386F094DB7
GO

Sequence cautioni

The sequence AAG52492 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG60091 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018364 Genomic DNA. Translation: AAG52492.1. Sequence problems.
AC073178 Genomic DNA. Translation: AAG60091.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34922.1.
CP002684 Genomic DNA. Translation: AEE34923.1.
BX814193 mRNA. No translation available.
RefSeqiNP_177101.2. NM_105609.4.
NP_974114.1. NM_202385.2.
UniGeneiAt.35423.

Genome annotation databases

EnsemblPlantsiAT1G69420.1; AT1G69420.1; AT1G69420.
AT1G69420.2; AT1G69420.2; AT1G69420.
GeneIDi843274.
GrameneiAT1G69420.1; AT1G69420.1; AT1G69420.
AT1G69420.2; AT1G69420.2; AT1G69420.
KEGGiath:AT1G69420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018364 Genomic DNA. Translation: AAG52492.1. Sequence problems.
AC073178 Genomic DNA. Translation: AAG60091.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE34922.1.
CP002684 Genomic DNA. Translation: AEE34923.1.
BX814193 mRNA. No translation available.
RefSeqiNP_177101.2. NM_105609.4.
NP_974114.1. NM_202385.2.
UniGeneiAt.35423.

3D structure databases

ProteinModelPortaliQ9C533.
SMRiQ9C533.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi28495. 1 interactor.
IntActiQ9C533. 1 interactor.
STRINGi3702.AT1G69420.1.

PTM databases

iPTMnetiQ9C533.

Proteomic databases

PaxDbiQ9C533.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G69420.1; AT1G69420.1; AT1G69420.
AT1G69420.2; AT1G69420.2; AT1G69420.
GeneIDi843274.
GrameneiAT1G69420.1; AT1G69420.1; AT1G69420.
AT1G69420.2; AT1G69420.2; AT1G69420.
KEGGiath:AT1G69420.

Organism-specific databases

AraportiAT1G69420.
TAIRilocus:2007086. AT1G69420.

Phylogenomic databases

eggNOGiKOG1311. Eukaryota.
COG5273. LUCA.
HOGENOMiHOG000242421.
InParanoidiQ9C533.
KOiK20027.
OMAiIIVVATC.
OrthoDBiEOG0936090U.
PhylomeDBiQ9C533.

Enzyme and pathway databases

BRENDAi2.3.1.225. 399.

Miscellaneous databases

PROiPR:Q9C533.

Gene expression databases

ExpressionAtlasiQ9C533. baseline and differential.
GenevisibleiQ9C533. AT.

Family and domain databases

InterProiView protein in InterPro
IPR001594. Palmitoyltrfase_DHHC.
PfamiView protein in Pfam
PF01529. zf-DHHC. 1 hit.
PROSITEiView protein in PROSITE
PS50216. DHHC. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiZDHC1_ARATH
AccessioniPrimary (citable) accession number: Q9C533
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: February 10, 2009
Last modified: April 12, 2017
This is version 97 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.