Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

WRKY transcription factor 6

Gene

WRKY6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771).2 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi306 – 372WRKYPROSITE-ProRule annotationAdd BLAST67

GO - Molecular functioni

  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: TAIR
  • transcription regulatory region DNA binding Source: TAIR

GO - Biological processi

  • cellular response to boron-containing substance deprivation Source: TAIR
  • cellular response to phosphate starvation Source: TAIR
  • ethylene-activated signaling pathway Source: UniProtKB-KW
  • negative regulation of transcription, DNA-templated Source: TAIR
  • response to chitin Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator, Repressor

Keywords - Biological processi

Ethylene signaling pathway, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
WRKY transcription factor 61 Publication
Alternative name(s):
WRKY DNA-binding protein 61 Publication
Short name:
AtWRKY61 Publication
Gene namesi
Name:WRKY61 Publication
Ordered Locus Names:At1g62300Imported
ORF Names:F19K23.22Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G62300.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi278K → E: Abolishes nuclear localization. 1 Publication1
Mutagenesisi296 – 297RK → AA: No effect on nuclear localization. 1 Publication2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001336481 – 553WRKY transcription factor 6Add BLAST553

Proteomic databases

PaxDbiQ9C519.

PTM databases

iPTMnetiQ9C519.

Expressioni

Tissue specificityi

Roots, leaves, shoots, flowers and siliques.

Inductioni

By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence.2 Publications

Gene expression databases

ExpressionAtlasiQ9C519. baseline and differential.
GenevisibleiQ9C519. AT.

Interactioni

Protein-protein interaction databases

BioGridi27748. 4 interactors.
IntActiQ9C519. 1 interactor.
MINTiMINT-8068075.
STRINGi3702.AT1G62300.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C519.
SMRiQ9C519.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the WRKY group II-b family.Curated
Contains 1 WRKY DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IENH. Eukaryota.
ENOG410YDVM. LUCA.
HOGENOMiHOG000241202.
InParanoidiQ9C519.
OMAiEMEDKRA.
OrthoDBiEOG09360C4S.
PhylomeDBiQ9C519.

Family and domain databases

Gene3Di2.20.25.80. 1 hit.
InterProiIPR003657. WRKY_dom.
[Graphical view]
PfamiPF03106. WRKY. 1 hit.
[Graphical view]
SMARTiSM00774. WRKY. 1 hit.
[Graphical view]
SUPFAMiSSF118290. SSF118290. 1 hit.
PROSITEiPS50811. WRKY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9C519-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRGWSGLTL DSSSLDLLNP NRISHKNHRR FSNPLAMSRI DEEDDQKTRI
60 70 80 90 100
STNGSEFRFP VSLSGIRDRE DEDFSSGVAG DNDREVPGEV DFFSDKKSRV
110 120 130 140 150
CREDDEGFRV KKEEQDDRTD VNTGLNLRTT GNTKSDESMI DDGESSEMED
160 170 180 190 200
KRAKNELVKL QDELKKMTMD NQKLRELLTQ VSNSYTSLQM HLVSLMQQQQ
210 220 230 240 250
QQNNKVIEAA EKPEETIVPR QFIDLGPTRA VGEAEDVSNS SSEDRTRSGG
260 270 280 290 300
SSAAERRSNG KRLGREESPE TESNKIQKVN STTPTTFDQT AEATMRKARV
310 320 330 340 350
SVRARSEAPM ISDGCQWRKY GQKMAKGNPC PRAYYRCTMA TGCPVRKQVQ
360 370 380 390 400
RCAEDRSILI TTYEGNHNHP LPPAAVAMAS TTTAAANMLL SGSMSSHDGM
410 420 430 440 450
MNPTNLLARA VLPCSTSMAT ISASAPFPTV TLDLTHSPPP PNGSNPSSSA
460 470 480 490 500
ATNNNHNSLM QRPQQQQQQM TNLPPGMLPH VIGQALYNQS KFSGLQFSGG
510 520 530 540 550
SPSTAAFSQS HAVADTITAL TADPNFTAAL AAVISSMING TNHHDGEGNN

KNQ
Length:553
Mass (Da):60,593
Last modified:June 1, 2001 - v1
Checksum:i9C75C89E4F16F297
GO

Sequence cautioni

The sequence AAB60774 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF331713 Genomic DNA. Translation: AAK01128.1.
AF331712 mRNA. Translation: AAK01127.1.
AC000375 Genomic DNA. Translation: AAB60774.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33948.1.
AF224702 mRNA. Translation: AAK28312.1.
PIRiF96649.
RefSeqiNP_564792.1. NM_104910.3.
UniGeneiAt.25260.

Genome annotation databases

EnsemblPlantsiAT1G62300.1; AT1G62300.1; AT1G62300.
GeneIDi842527.
GrameneiAT1G62300.1; AT1G62300.1; AT1G62300.
KEGGiath:AT1G62300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF331713 Genomic DNA. Translation: AAK01128.1.
AF331712 mRNA. Translation: AAK01127.1.
AC000375 Genomic DNA. Translation: AAB60774.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33948.1.
AF224702 mRNA. Translation: AAK28312.1.
PIRiF96649.
RefSeqiNP_564792.1. NM_104910.3.
UniGeneiAt.25260.

3D structure databases

ProteinModelPortaliQ9C519.
SMRiQ9C519.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27748. 4 interactors.
IntActiQ9C519. 1 interactor.
MINTiMINT-8068075.
STRINGi3702.AT1G62300.1.

PTM databases

iPTMnetiQ9C519.

Proteomic databases

PaxDbiQ9C519.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G62300.1; AT1G62300.1; AT1G62300.
GeneIDi842527.
GrameneiAT1G62300.1; AT1G62300.1; AT1G62300.
KEGGiath:AT1G62300.

Organism-specific databases

TAIRiAT1G62300.

Phylogenomic databases

eggNOGiENOG410IENH. Eukaryota.
ENOG410YDVM. LUCA.
HOGENOMiHOG000241202.
InParanoidiQ9C519.
OMAiEMEDKRA.
OrthoDBiEOG09360C4S.
PhylomeDBiQ9C519.

Miscellaneous databases

PROiQ9C519.

Gene expression databases

ExpressionAtlasiQ9C519. baseline and differential.
GenevisibleiQ9C519. AT.

Family and domain databases

Gene3Di2.20.25.80. 1 hit.
InterProiIPR003657. WRKY_dom.
[Graphical view]
PfamiPF03106. WRKY. 1 hit.
[Graphical view]
SMARTiSM00774. WRKY. 1 hit.
[Graphical view]
SUPFAMiSSF118290. SSF118290. 1 hit.
PROSITEiPS50811. WRKY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiWRKY6_ARATH
AccessioniPrimary (citable) accession number: Q9C519
Secondary accession number(s): O04594, Q9C5T1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.