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Protein

WPP domain-containing protein 2

Gene

WPP2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regulates the mitotic activity in roots. Plays a role with HSP70-1 in facilitating WIT1 nuclear envelope targeting.2 Publications

GO - Biological processi

  • lateral root development Source: TAIR
  • mitotic cell cycle Source: TAIR

Names & Taxonomyi

Protein namesi
Recommended name:
WPP domain-containing protein 2
Alternative name(s):
MFP1 attachment factor 2
Gene namesi
Name:WPP2
Synonyms:MAF2
Ordered Locus Names:At1g47200
ORF Names:F2G19.18, F8G22.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G47200.
TAIRilocus:2036736. AT1G47200.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003471921 – 180WPP domain-containing protein 2Add BLAST180

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei173PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9C500.

PTM databases

iPTMnetiQ9C500.

Expressioni

Tissue specificityi

Expressed in roots, stems, leaves and flowers.1 Publication

Gene expression databases

ExpressionAtlasiQ9C500. baseline and differential.
GenevisibleiQ9C500. AT.

Interactioni

Subunit structurei

Binds to FPP proteins (By similarity). Interacts with WAP, WIP1, WIP2 and WIP3 through its WPP domain. Interacts with WIT1 and HSP70-1.By similarity4 Publications

Protein-protein interaction databases

BioGridi26348. 11 interactors.
IntActiQ9C500. 6 interactors.
STRINGi3702.AT1G47200.1.

Structurei

3D structure databases

ProteinModelPortaliQ9C500.
SMRiQ9C500.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni44 – 147WPPAdd BLAST104

Domaini

The WPP domain is required for the nuclear envelope localization.By similarity

Phylogenomic databases

eggNOGiENOG410J184. Eukaryota.
ENOG410YXFU. LUCA.
HOGENOMiHOG000239842.
InParanoidiQ9C500.
OMAiISAMTDP.
OrthoDBiEOG09360SX3.
PhylomeDBiQ9C500.

Family and domain databases

Gene3Di1.10.246.200. 1 hit.
InterProiView protein in InterPro
IPR025265. WPP_dom.
IPR038214. WPP_sf.
PfamiView protein in Pfam
PF13943. WPP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9C500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETAETINT TISSPPPESE SSTTISAMTD PTSQEAASKD TDLTKEAESE
60 70 80 90 100
KKPGGISLRI WPPTQKTRDA VLNRLIETLS TESILSKRYG TLKSDDATTV
110 120 130 140 150
AKLIEEEAYG VASNAVSSDD DGIKILELYS KEISKRMLES VKARSNASVG
160 170 180
NGSVEDANTD ASEVSKDDAG PASEEEKSEA
Length:180
Mass (Da):19,134
Last modified:June 1, 2001 - v1
Checksum:iF71F090976FA3826
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti172A → G in AAM62902 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079677 Genomic DNA. Translation: AAG52640.1.
AC083835 Genomic DNA. Translation: AAG50616.1.
CP002684 Genomic DNA. Translation: AEE32136.1.
AY072148 mRNA. Translation: AAL59970.1.
AY096476 mRNA. Translation: AAM20116.1.
AY085683 mRNA. Translation: AAM62902.1.
PIRiF96512.
RefSeqiNP_564498.1. NM_103613.3.
UniGeneiAt.17221.

Genome annotation databases

EnsemblPlantsiAT1G47200.1; AT1G47200.1; AT1G47200.
GeneIDi841123.
GrameneiAT1G47200.1; AT1G47200.1; AT1G47200.
KEGGiath:AT1G47200.

Similar proteinsi

Entry informationi

Entry nameiWPP2_ARATH
AccessioniPrimary (citable) accession number: Q9C500
Secondary accession number(s): Q8LE13
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome