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Protein

Putative D-lactate dehydrogenase C713.03, mitochondrial

Gene

SPBC713.03

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H+.

Cofactori

FADCurated

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandFAD, Flavoprotein

Enzyme and pathway databases

ReactomeiR-SPO-880009 Interconversion of 2-oxoglutarate and 2-hydroxyglutarate

Names & Taxonomyi

Protein namesi
Recommended name:
Putative D-lactate dehydrogenase C713.03, mitochondrial (EC:1.1.2.4)
Gene namesi
ORF Names:SPBC713.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC713.03
PomBaseiSPBC713.03

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000317236? – 526Putative D-lactate dehydrogenase C713.03, mitochondrial
Transit peptidei1 – ?MitochondrionSequence analysis

Proteomic databases

MaxQBiQ9C1X2
PaxDbiQ9C1X2
PRIDEiQ9C1X2

Interactioni

Protein-protein interaction databases

BioGridi277666, 12 interactors
STRINGi4896.SPBC713.03.1

Structurei

3D structure databases

ProteinModelPortaliQ9C1X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 272FAD-binding PCMH-typePROSITE-ProRule annotationAdd BLAST180

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000230997
InParanoidiQ9C1X2
KOiK21618
OMAiNEDWMRK
OrthoDBiEOG092C1XYI
PhylomeDBiQ9C1X2

Family and domain databases

Gene3Di1.10.45.10, 1 hit
3.30.43.10, 1 hit
InterProiView protein in InterPro
IPR016166 FAD-bd_2
IPR036318 FAD-bd_2-like_sf
IPR016167 FAD-bd_2_sub1
IPR016164 FAD-linked_Oxase-like_C
IPR004113 FAD-linked_oxidase_C
IPR006094 Oxid_FAD_bind_N
IPR016171 Vanillyl_alc_oxidase_C-sub2
PfamiView protein in Pfam
PF02913 FAD-oxidase_C, 1 hit
PF01565 FAD_binding_4, 1 hit
SUPFAMiSSF55103 SSF55103, 1 hit
SSF56176 SSF56176, 1 hit
PROSITEiView protein in PROSITE
PS51387 FAD_PCMH, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9C1X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSLQCRRVI PFGKLSLSLH APRNALRFVH KPAFTFESYK SLHRDPKYAK
60 70 80 90 100
LSEQDVQVFK SIIGKDGSLI DGLDKSTDPA DLDAFNIDWM NKYRGKTQLA
110 120 130 140 150
LKPKTTQQVS EILKYCNQKK LAVVPQGGNT GLVGGSVPVF DEIVLNLGLM
160 170 180 190 200
NQIHTFDEIS GVITLDSGVI LENADNFLAE KGYMFPLDLG AKGSCQVGGC
210 220 230 240 250
AATAAGGLRL LRYGSLHGSI LGMEAVLPDG TILDNLVTLR KDNTGLDIKQ
260 270 280 290 300
LFIGSEGYLG VITKLSVICP KRPSSTNVAF FGVPSYENVL KAFSETRSHL
310 320 330 340 350
TEILSAFELM DNTSQTLVDK YSGTQRPLED EHPFYVLVET QGSNKEHDEQ
360 370 380 390 400
KITALVEDLL EKEIISDGVL AQDESQLRVL WERREGITEC LAKAGSGVYK
410 420 430 440 450
YDVSLPLPVL YDLVNDTKKR LIEFNLLDDT PEHPVIDVVG FGHMGDGNLH
460 470 480 490 500
LNIAVRQFDK RVEKCLEPWV YEWVSRHRGS ISAEHGLGLL KKPFVGYSKS
510 520
KEMIHLMKTL KNVFDPNGIM LPYKYV
Length:526
Mass (Da):58,473
Last modified:June 1, 2001 - v1
Checksum:i00FAF5ABA81EBC11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAC22604.1
RefSeqiNP_595342.1, NM_001021250.2

Genome annotation databases

EnsemblFungiiSPBC713.03.1; SPBC713.03.1:pep; SPBC713.03
GeneIDi2541151
KEGGispo:SPBC713.03

Similar proteinsi

Entry informationi

Entry nameiYN53_SCHPO
AccessioniPrimary (citable) accession number: Q9C1X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health