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Q9C1W9

- DNLI3_SCHPO

UniProt

Q9C1W9 - DNLI3_SCHPO

Protein

DNA ligase 3

Gene

adl1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).PROSITE-ProRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei433 – 4331N6-AMP-lysine intermediatePROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA biosynthetic process Source: PomBase
    2. DNA ligation involved in DNA repair Source: InterPro
    3. DNA recombination Source: InterPro
    4. DNA replication Source: UniProtKB-KW
    5. signal transduction Source: InterPro

    Keywords - Molecular functioni

    Ligase

    Keywords - Biological processi

    DNA replication

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligase 3 (EC:6.5.1.1)
    Alternative name(s):
    DNA ligase III
    Polydeoxyribonucleotide synthase [ATP] 3
    Gene namesi
    Name:adl1
    Synonyms:lig3
    ORF Names:SPBC713.06
    OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    Taxonomic identifieri284812 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
    ProteomesiUP000002485: Chromosome II

    Organism-specific databases

    PomBaseiSPBC713.06.

    Subcellular locationi

    Nucleus 1 Publication

    GO - Cellular componenti

    1. nucleus Source: PomBase

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 774774DNA ligase 3PRO_0000372334Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-4702364.
    STRINGi4896.SPBC713.06-1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9C1W9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.Curated

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000036006.
    KOiK10747.
    OMAiFIMEGEV.
    OrthoDBiEOG7TXKRG.
    PhylomeDBiQ9C1W9.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR000014. PAS.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00091. PAS. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9C1W9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPKKRMKNG SSLKSTSKKG EKSRNIITIQ DLFSKREAQL TDTPNKLLTD    50
    HDQSASDYAY ALKLQQLFDS ENQATAPEKL PKDVIIPEEE YHTDTFNVVK 100
    ESNDKPKENL VTSEECKASF FSTDSVNKDS TIDYDALQKD PLTYVKSCRA 150
    RFVSKDTKSF SYSSLANTFS LISSTKSRIR IVTLLTNFLL TLLYADPDSL 200
    IATVWLCTNS IAPNFYGKNL GVGPAMYSKA LKEVCGITAS ALKNLWNKYG 250
    DPGDVAFEAK VSVRTLSRPE PLTIKKVYST LLKIADSNGN GAQNRKLELT 300
    KFLLISSNAE EVRYIGRSIM QNLRIGAVQN TMLASLSKAF FIFDNQNEIF 350
    NFNSDSLQQQ FRQGEEIVKQ SFFQVPDYNI LVATLLREGI ENLKDNMSIR 400
    PGIPVKPMLG SITKNLQHML ERLTDHNFSC EFKYDGQRAQ IHCDRLGNIK 450
    IFSRHLEEIT GRFPDVIEVA QLALKHSCDF IIEGELVAID KSNGQILDFQ 500
    KLSTRERKKV TVADITIDVC VFVFDIMFCD GKSCLQMPLI ERRRMFFEHF 550
    NLIPNRFQFV SSLETNEEQS IQEFFSLAIT NKCEGLMVKV LNGTNSKFPS 600
    TYEPDKRGEG WIKVKQDYDD EFESLDLVPI GAWYGNGRKA GWFSPILLAV 650
    YNPDTGAYEA VCKCMSGFSD QFYKELTQKY SLESGNSSLK PIYNFCETGK 700
    VTPQIYFAPQ EVWEIKGAQI TSSPAYKAAL GLIQDDRGLS IRFPRFIRVR 750
    SDKGPEDAST NSILADMYMK QLNT 774
    Length:774
    Mass (Da):87,587
    Last modified:June 1, 2001 - v1
    Checksum:i9D69F9EA510F78FF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329671 Genomic DNA. Translation: CAC22607.1.
    RefSeqiNP_595345.1. NM_001021253.2.

    Genome annotation databases

    EnsemblFungiiSPBC713.06.1; SPBC713.06.1:pep; SPBC713.06.
    GeneIDi2541111.
    KEGGispo:SPBC713.06.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU329671 Genomic DNA. Translation: CAC22607.1 .
    RefSeqi NP_595345.1. NM_001021253.2.

    3D structure databases

    ProteinModelPortali Q9C1W9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4702364.
    STRINGi 4896.SPBC713.06-1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii SPBC713.06.1 ; SPBC713.06.1:pep ; SPBC713.06 .
    GeneIDi 2541111.
    KEGGi spo:SPBC713.06.

    Organism-specific databases

    PomBasei SPBC713.06.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000036006.
    KOi K10747.
    OMAi FIMEGEV.
    OrthoDBi EOG7TXKRG.
    PhylomeDBi Q9C1W9.

    Miscellaneous databases

    NextBioi 20802224.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR000014. PAS.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00091. PAS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Schizosaccharomyces pombe."
      Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
      , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
      Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 972 / ATCC 24843.
    2. "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe."
      Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M.
      Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiDNLI3_SCHPO
    AccessioniPrimary (citable) accession number: Q9C1W9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Schizosaccharomyces pombe
      Schizosaccharomyces pombe: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3