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Protein

DNA ligase 3

Gene

adl1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei433N6-AMP-lysine intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
Biological processDNA replication
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligase 3 (EC:6.5.1.1PROSITE-ProRule annotation)
Alternative name(s):
DNA ligase III
Polydeoxyribonucleotide synthase [ATP] 3
Gene namesi
Name:adl1
Synonyms:lig3
ORF Names:SPBC713.06
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC713.06
PomBaseiSPBC713.06 adl1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003723341 – 774DNA ligase 3Add BLAST774

Proteomic databases

PaxDbiQ9C1W9
PRIDEiQ9C1W9

PTM databases

iPTMnetiQ9C1W9

Interactioni

Protein-protein interaction databases

STRINGi4896.SPBC713.06.1

Structurei

3D structure databases

ProteinModelPortaliQ9C1W9
SMRiQ9C1W9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.Curated

Phylogenomic databases

HOGENOMiHOG000036006
InParanoidiQ9C1W9
KOiK10747
OMAiGIMVKIL
OrthoDBiEOG092C0FHN
PhylomeDBiQ9C1W9

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

Q9C1W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKKRMKNG SSLKSTSKKG EKSRNIITIQ DLFSKREAQL TDTPNKLLTD
60 70 80 90 100
HDQSASDYAY ALKLQQLFDS ENQATAPEKL PKDVIIPEEE YHTDTFNVVK
110 120 130 140 150
ESNDKPKENL VTSEECKASF FSTDSVNKDS TIDYDALQKD PLTYVKSCRA
160 170 180 190 200
RFVSKDTKSF SYSSLANTFS LISSTKSRIR IVTLLTNFLL TLLYADPDSL
210 220 230 240 250
IATVWLCTNS IAPNFYGKNL GVGPAMYSKA LKEVCGITAS ALKNLWNKYG
260 270 280 290 300
DPGDVAFEAK VSVRTLSRPE PLTIKKVYST LLKIADSNGN GAQNRKLELT
310 320 330 340 350
KFLLISSNAE EVRYIGRSIM QNLRIGAVQN TMLASLSKAF FIFDNQNEIF
360 370 380 390 400
NFNSDSLQQQ FRQGEEIVKQ SFFQVPDYNI LVATLLREGI ENLKDNMSIR
410 420 430 440 450
PGIPVKPMLG SITKNLQHML ERLTDHNFSC EFKYDGQRAQ IHCDRLGNIK
460 470 480 490 500
IFSRHLEEIT GRFPDVIEVA QLALKHSCDF IIEGELVAID KSNGQILDFQ
510 520 530 540 550
KLSTRERKKV TVADITIDVC VFVFDIMFCD GKSCLQMPLI ERRRMFFEHF
560 570 580 590 600
NLIPNRFQFV SSLETNEEQS IQEFFSLAIT NKCEGLMVKV LNGTNSKFPS
610 620 630 640 650
TYEPDKRGEG WIKVKQDYDD EFESLDLVPI GAWYGNGRKA GWFSPILLAV
660 670 680 690 700
YNPDTGAYEA VCKCMSGFSD QFYKELTQKY SLESGNSSLK PIYNFCETGK
710 720 730 740 750
VTPQIYFAPQ EVWEIKGAQI TSSPAYKAAL GLIQDDRGLS IRFPRFIRVR
760 770
SDKGPEDAST NSILADMYMK QLNT
Length:774
Mass (Da):87,587
Last modified:June 1, 2001 - v1
Checksum:i9D69F9EA510F78FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAC22607.1
RefSeqiNP_595345.1, NM_001021253.2

Genome annotation databases

EnsemblFungiiSPBC713.06.1; SPBC713.06.1:pep; SPBC713.06
GeneIDi2541111
KEGGispo:SPBC713.06

Similar proteinsi

Entry informationi

Entry nameiDNLI3_SCHPO
AccessioniPrimary (citable) accession number: Q9C1W9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: June 1, 2001
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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