Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9C1W8 (PPN1_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endopolyphosphatase
EC=3.6.1.10
Gene names
Name:ppn1
ORF Names:SPBC713.07c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length577 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the hydrolysis of inorganic polyphosphate (poly P) chains of many hundreds of phosphate residues into shorter lengths By similarity.

Catalytic activity

Polyphosphate + n H2O = (n+1) oligophosphate.

Subcellular location

Vacuole membrane; Single-pass type II membrane protein.

Post-translational modification

Processing by proteases in the vacuole may be required for activation By similarity.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 577577Endopolyphosphatase
PRO_0000058549

Regions

Topological domain1 – 22Cytoplasmic Potential
Transmembrane3 – 2321Helical; Signal-anchor for type II membrane protein; Potential
Topological domain24 – 577554Vacuolar Potential
Compositional bias436 – 4438Poly-Lys
Compositional bias446 – 4549Poly-Lys
Compositional bias550 – 5534Poly-Lys

Amino acid modifications

Glycosylation3631N-linked (GlcNAc...) Potential
Glycosylation3701N-linked (GlcNAc...) Potential
Glycosylation3751N-linked (GlcNAc...) Potential
Glycosylation3991N-linked (GlcNAc...) Potential
Glycosylation4811N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q9C1W8 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: D5EC6913A6E89647

FASTA57766,026
        10         20         30         40         50         60 
MRPSVITVAV LFVQSTWASF AFGNPMSMRN KAHTNDLVNS KGKPLVGRFL HITDMHPDIY 

        70         80         90        100        110        120 
YEKGSTVDHY CHSYDHNSDD TPLGKSKVGY LSPGPGYECD SSPALIDKTL EWLKEHQDDV 

       130        140        150        160        170        180 
LGGIDFILWT GDNSRHDNDN HFPRTQSEIL ASNEDLVNKM IEAFPDVPIV SAIGNNDIYP 

       190        200        210        220        230        240 
HNIMEAGPSS MTRQLAGAWD ALIPYEERHT FEKGSYYLCD VIPDKLAAIS INTLYLSNKN 

       250        260        270        280        290        300 
AAVDGCPDDN LDEPGSLFMR WFKIQLEAYR LKGMKVWLLG HIPPTRGQWY EDCYTSFTDL 

       310        320        330        340        350        360 
LYEFRDIIVG QLYGHMNINH FVFLEFDKLP VDTESYGIKS AQPKYVKSLI DAQYAELPTF 

       370        380        390        400        410        420 
PENLTEEFLN GTVGNYSLAT VGGSIIPEMF PTFRVYEYNI SDIANQLDDR EELTEITSFN 

       430        440        450        460        470        480 
WETLEEQSQS DYEIDKKKKK KKKNNKKKKK NKRKNIKPGP LGPAYVPSLF TPISFKQYFL 

       490        500        510        520        530        540 
NTSNYMDATK DTEISYELLY TSKDSPYNMP DLTVPEYMRL AKRIATCDKP EDPHQFKLQS 

       550        560        570 
GDQNTFRISK KKKPSICPIA YTYLWHAYIG SISDFED

« Hide

References

[1]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU329671 Genomic DNA. Translation: CAC22608.1.
RefSeqNP_595346.1. NM_001021254.1.

3D structure databases

ProteinModelPortalQ9C1W8.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9C1W8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC713.07c.1; SPBC713.07c.1:pep; SPBC713.07c.
GeneID2541140.
GenomeReviewsGene locus ppn1 in contig CU329671_GR.
KEGGspo:SPBC713.07c.
NMPDRfig|4896.1.peg.1212.

Organism-specific databases

GeneDB_SpombeSPBC713.07c.

Phylogenomic databases

eggNOGfuNOG05066.
GeneTreeEFGT00050000001520.
OMAAISASHP.
OrthoDBEOG4TMV9Q.

Gene expression databases

ArrayExpressQ9C1W8.

Family and domain databases

InterProIPR012358. EndopolyPtase_N1.
IPR004843. Metallo_PEstase_dom.
[Graphical view]
KOK06018.
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF027093. EndopolyPtase_N1. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPN1_SCHPO
AccessionPrimary (citable) accession number: Q9C1W8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents