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Protein

Plasma membrane proteolipid 3

Gene

pmp3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the regulation of membrane potential. Could mediate a proton leak. Regulated by the spc1-atf1 pathway and so expression is stress-induced.1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Plasma membrane proteolipid 3
Gene namesi
Name:pmp3
ORF Names:SPBC713.11c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC713.11c.
PomBaseiSPBC713.11c. pmp3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002479141 – 57Plasma membrane proteolipid 3Add BLAST57

Interactioni

Protein-protein interaction databases

BioGridi277644. 11 interactors.
MINTiMINT-4702315.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0057 (PMP3) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000274029.
InParanoidiQ9C1W4.
OMAiNADFFIN.
OrthoDBiEOG092C5YWZ.

Family and domain databases

InterProiIPR000612. PMP3.
[Graphical view]
PANTHERiPTHR21659. PTHR21659. 1 hit.
PfamiPF01679. Pmp3. 1 hit.
[Graphical view]
PROSITEiPS01309. UPF0057. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9C1W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTGSDIFK VIFAIILPPL GVFLERGCGA DVIINILLCC LGYVPGIIHA

LYIILKY
Length:57
Mass (Da):6,179
Last modified:July 11, 2012 - v2
Checksum:i1652B222A2E3B28D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAC22612.2.
RefSeqiNP_595350.2. NM_001021258.2.

Genome annotation databases

EnsemblFungiiSPBC713.11c.1; SPBC713.11c.1:pep; SPBC713.11c.
GeneIDi2541129.
KEGGispo:SPBC713.11c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAC22612.2.
RefSeqiNP_595350.2. NM_001021258.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi277644. 11 interactors.
MINTiMINT-4702315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC713.11c.1; SPBC713.11c.1:pep; SPBC713.11c.
GeneIDi2541129.
KEGGispo:SPBC713.11c.

Organism-specific databases

EuPathDBiFungiDB:SPBC713.11c.
PomBaseiSPBC713.11c. pmp3.

Phylogenomic databases

HOGENOMiHOG000274029.
InParanoidiQ9C1W4.
OMAiNADFFIN.
OrthoDBiEOG092C5YWZ.

Miscellaneous databases

PROiQ9C1W4.

Family and domain databases

InterProiIPR000612. PMP3.
[Graphical view]
PANTHERiPTHR21659. PTHR21659. 1 hit.
PfamiPF01679. Pmp3. 1 hit.
[Graphical view]
PROSITEiPS01309. UPF0057. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPMP3_SCHPO
AccessioniPrimary (citable) accession number: Q9C1W4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 11, 2012
Last modified: November 2, 2016
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.