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Protein

Plasma membrane proteolipid 3

Gene

pmp3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the regulation of membrane potential. Could mediate a proton leak. Regulated by the spc1-atf1 pathway and so expression is stress-induced.1 Publication

Names & Taxonomyi

Protein namesi
Recommended name:
Plasma membrane proteolipid 3
Gene namesi
Name:pmp3
ORF Names:SPBC713.11c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC713.11c.
PomBaseiSPBC713.11c. pmp3.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • cytoplasm Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002479141 – 57Plasma membrane proteolipid 3Add BLAST57

Interactioni

Protein-protein interaction databases

BioGridi277644. 11 interactors.
MINTiMINT-4702315.
STRINGi4896.SPBC713.11c.1.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0057 (PMP3) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000274029.
InParanoidiQ9C1W4.
OMAiQFWLNIL.
OrthoDBiEOG092C5YWZ.

Family and domain databases

InterProiView protein in InterPro
IPR000612. PMP3.
PANTHERiPTHR21659. PTHR21659. 1 hit.
PfamiView protein in Pfam
PF01679. Pmp3. 1 hit.
PROSITEiView protein in PROSITE
PS01309. UPF0057. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9C1W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTGSDIFK VIFAIILPPL GVFLERGCGA DVIINILLCC LGYVPGIIHA

LYIILKY
Length:57
Mass (Da):6,179
Last modified:July 11, 2012 - v2
Checksum:i1652B222A2E3B28D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA. Translation: CAC22612.2.
RefSeqiNP_595350.2. NM_001021258.2.

Genome annotation databases

EnsemblFungiiSPBC713.11c.1; SPBC713.11c.1:pep; SPBC713.11c.
GeneIDi2541129.
KEGGispo:SPBC713.11c.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPMP3_SCHPO
AccessioniPrimary (citable) accession number: Q9C1W4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 11, 2012
Last modified: July 5, 2017
This is version 82 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries