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Q9C1T1 (PHYA_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-phytase A

EC=3.1.3.8
Alternative name(s):
3 phytase A
Myo-inositol hexakisphosphate phosphohydrolase A
Myo-inositol-hexaphosphate 3-phosphohydrolase A
Gene names
Name:phyA
ORF Names:AO090023000692
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length466 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the hydrolysis of inorganic orthophosphate from phytate.

Catalytic activity

Myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.

Subcellular location

Secreted.

Sequence similarities

Belongs to the histidine acid phosphatase family.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionHydrolase
   PTMDisulfide bond
Glycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processmyo-inositol hexakisphosphate dephosphorylation

Inferred from direct assay PubMed 17270723. Source: ASPGD

   Cellular_componentextracellular region

Inferred from direct assay PubMed 17270723. Source: ASPGD

   Molecular_function3-phytase activity

Inferred from direct assay PubMed 17270723. Source: ASPGD

acid phosphatase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 4664473-phytase A
PRO_0000043346

Sites

Active site811Nucleophile By similarity
Active site3611Proton donor By similarity

Amino acid modifications

Glycosylation1041N-linked (GlcNAc...) Potential
Glycosylation1191N-linked (GlcNAc...) Potential
Glycosylation2061N-linked (GlcNAc...) Potential
Glycosylation2191N-linked (GlcNAc...) Potential
Glycosylation3381N-linked (GlcNAc...) Potential
Glycosylation3511N-linked (GlcNAc...) Potential
Glycosylation3751N-linked (GlcNAc...) Potential
Disulfide bond30 ↔ 39 By similarity
Disulfide bond70 ↔ 413 By similarity
Disulfide bond214 ↔ 464 By similarity
Disulfide bond263 ↔ 281 By similarity
Disulfide bond435 ↔ 443 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9C1T1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 8033BED57FBA2791

FASTA46651,257
        10         20         30         40         50         60 
MAVLSVLLPI TFLLSSVTGT PVTSPRQQSC NTVDEGYQCF SGVSHLWGQY SPYFSVDDES 

        70         80         90        100        110        120 
SLSEDVPDHC QVTFAQVLSR HGARYPTKSK SEKYAKLIKA VQHNATSFSG KYAFLKSYNY 

       130        140        150        160        170        180 
SLGADDLTPF GENQLVDSGI KFYQRYEELA KNVVPFIRAS GSDRVIASGE KFIEGFQKAK 

       190        200        210        220        230        240 
LGDSKSKRGQ PAPIVNVVIT ETEGFNNTLD HSLCTAFENS TTGDDAEDKF TAVFTPSIVE 

       250        260        270        280        290        300 
RLEKDLPGTT LSSKEVVYLM DMCSFDTIAL TRDGSRLSPF CALFTQEEWA QYDYLQSVSK 

       310        320        330        340        350        360 
YYGYGGGNPL GPAQGIGFAN ELIARLTKSP VKDHTTTNTT LDSNPATFPL NATLYADFSH 

       370        380        390        400        410        420 
DNTMTSVFFA LGLYNTTEPL SQTSVQSTEE TNGYSSARTV PFGARAYVEM MQCTDEKEPL 

       430        440        450        460 
VRVLVNDRVI PLQGCDADEY GRCKRDDFVE GLSFVTSGGN WGECFA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB042805 mRNA. Translation: BAB40715.1.
AP007157 Genomic DNA. Translation: BAE59208.1.
RefSeqXP_001821210.1. XM_001821158.2.

3D structure databases

ProteinModelPortalQ9C1T1.
SMRQ9C1T1. Positions 30-465.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00007793; CADAORAP00007634; CADAORAG00007793.
GeneID5993212.
KEGGaor:AOR_1_1198144.

Phylogenomic databases

HOGENOMHOG000189493.
OrthoDBEOG7QC85C.

Family and domain databases

Gene3D3.40.50.1240. 1 hit.
InterProIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
IPR016274. Histidine_acid_Pase_euk.
[Graphical view]
PfamPF00328. His_Phos_2. 1 hit.
[Graphical view]
PIRSFPIRSF000894. Acid_phosphatase. 1 hit.
SUPFAMSSF53254. SSF53254. 1 hit.
PROSITEPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHYA_ASPOR
AccessionPrimary (citable) accession number: Q9C1T1
Secondary accession number(s): Q2UGV7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: June 1, 2001
Last modified: June 11, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families