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Protein

Putative agmatinase 3

Gene

SPAPB24D3.03

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Agmatine + H2O = putrescine + urea.By similarity

Cofactori

Mn2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi198Manganese 1PROSITE-ProRule annotation1
Metal bindingi222Manganese 1PROSITE-ProRule annotation1
Metal bindingi222Manganese 2PROSITE-ProRule annotation1
Metal bindingi224Manganese 2PROSITE-ProRule annotation1
Metal bindingi226Manganese 1PROSITE-ProRule annotation1
Metal bindingi319Manganese 1PROSITE-ProRule annotation1
Metal bindingi319Manganese 2PROSITE-ProRule annotation1
Metal bindingi321Manganese 2PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-SPO-351143 Agmatine biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Putative agmatinase 3 (EC:3.5.3.11By similarity)
Alternative name(s):
Agmatine ureohydrolase 3
Short name:
AUH 3
Gene namesi
ORF Names:SPAPB24D3.03
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAPB24D3.03
PomBaseiSPAPB24D3.03

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000031176022 – 408Putative agmatinase 3Add BLAST387

Proteomic databases

PaxDbiQ9C0Y9
PRIDEiQ9C0Y9

Interactioni

Protein-protein interaction databases

BioGridi279984, 6 interactors
STRINGi4896.SPAPB24D3.03.1

Structurei

3D structure databases

ProteinModelPortaliQ9C0Y9
SMRiQ9C0Y9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000204320
InParanoidiQ9C0Y9
KOiK01480
OMAiFDGGTSH
OrthoDBiEOG092C3B4E

Family and domain databases

InterProiView protein in InterPro
IPR006035 Ureohydrolase
IPR023696 Ureohydrolase_dom_sf
IPR020855 Ureohydrolase_Mn_BS
PfamiView protein in Pfam
PF00491 Arginase, 1 hit
PIRSFiPIRSF036979 Arginase, 1 hit
PRINTSiPR00116 ARGINASE
SUPFAMiSSF52768 SSF52768, 1 hit
PROSITEiView protein in PROSITE
PS01053 ARGINASE_1, 1 hit
PS51409 ARGINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9C0Y9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKSVEWFTWG VFLLLSGFGE AGRMGLGFQE KNPVFVKEKQ SPFYAVPSNY
60 70 80 90 100
EEVEFSSIVE PMYSGIATFG RLENVECLSK RSEDFDIAFI GMPFDTGTSY
110 120 130 140 150
RPGARFGPSS LREGSRRINT KYGAVNVPLE INPFKSWAKL VDCGDIPVTT
160 170 180 190 200
YDILKAMDQL ESAYFQLIAR KPSSFTDHDG FAKNDTVLPR VLSLGGDHTI
210 220 230 240 250
VLPILRALHR VYGQPISVIH FDSHLDTWAP GLIGDGDEAD GINHGSYFYF
260 270 280 290 300
ASQEGIMSKD ANIHAGIRTP ISSFSDYDDD VDCGFKIIEA REIDDLGIDG
310 320 330 340 350
IVKKIRDRVG DNLVYLSIDI DVLDPAFAPA TGTPETGGWS SREMRAILRG
360 370 380 390 400
LQGLKFVGAD LVEVAPAYDV AEITSLAGAQ LLFDIVSMMV KYPLVKEADL

SRYMPIHK
Length:408
Mass (Da):45,085
Last modified:June 13, 2012 - v2
Checksum:i3BB0F4614304C536
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA Translation: CAC36899.2
RefSeqiNP_593990.2, NM_001019416.2

Genome annotation databases

EnsemblFungiiSPAPB24D3.03.1; SPAPB24D3.03.1:pep; SPAPB24D3.03
GeneIDi2543569
KEGGispo:SPAPB24D3.03

Similar proteinsi

Entry informationi

Entry nameiSPEB3_SCHPO
AccessioniPrimary (citable) accession number: Q9C0Y9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: June 13, 2012
Last modified: March 28, 2018
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health