Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ATP-binding cassette transporter pdr1

Gene

pdr1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi794 – 8018ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-1369062. ABC transporters in lipid homeostasis.
R-SPO-265473. Trafficking of dietary sterols.

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-binding cassette transporter pdr1
Short name:
ABC transporter pdr1
Gene namesi
Name:pdr1
ORF Names:SPAPB24D3.09c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAPB24D3.09c.
PomBaseiSPAPB24D3.09c. pdr1.

Subcellular locationi

  • Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei431 – 45121HelicalSequence analysisAdd
BLAST
Transmembranei466 – 48621HelicalSequence analysisAdd
BLAST
Transmembranei512 – 53221HelicalSequence analysisAdd
BLAST
Transmembranei543 – 56321HelicalSequence analysisAdd
BLAST
Transmembranei572 – 59221HelicalSequence analysisAdd
BLAST
Transmembranei680 – 70021HelicalSequence analysisAdd
BLAST
Transmembranei1095 – 111521HelicalSequence analysisAdd
BLAST
Transmembranei1166 – 118621HelicalSequence analysisAdd
BLAST
Transmembranei1208 – 122821HelicalSequence analysisAdd
BLAST
Transmembranei1245 – 126521HelicalSequence analysisAdd
BLAST
Transmembranei1361 – 138121HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13961396ATP-binding cassette transporter pdr1PRO_0000362140Add
BLAST

Proteomic databases

MaxQBiQ9C0Y5.

Interactioni

Protein-protein interaction databases

BioGridi279785. 12 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9C0Y5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini73 – 320248ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini412 – 622211ABC transmembrane type-2 1Add
BLAST
Domaini758 – 1001244ABC transporter 2PROSITE-ProRule annotationAdd
BLAST
Domaini1071 – 1286216ABC transmembrane type-2 2Add
BLAST

Sequence similaritiesi

Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ9C0Y5.
OMAiPRSANEF.
OrthoDBiEOG7XDBQ6.
PhylomeDBiQ9C0Y5.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR010929. PDR_CDR_ABC.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF06422. PDR_CDR. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9C0Y5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQEKGKGD LDDPNSKNTK CPDKFEQKVE EYLEVLNELH LTGRTSGFCM
60 70 80 90 100
RNFTVEGAFN PKFQIRSFFA QLLHPINIIF RTGPKRDIIP LVKGFDGYLQ
110 120 130 140 150
PGSSLLVLGH EGSGGSTLLK ALCGIVEENE RLNGSLHYDG LDYKIAHSQF
160 170 180 190 200
KADLSYCGEG HSKVATITVR RLLEFVCSCR LPASKYDHPR SHYIRRICEI
210 220 230 240 250
IRDAFDLGDF YNHRILRVFN SGDQIKVDVA QTMCARPLIQ CWDNNMRDFD
260 270 280 290 300
SISVIDILSR IKVLSHKLGT TLVAIVSQAS DRIFHMFDMV TLMYEGEQIF
310 320 330 340 350
YGPTSRLKPY FLDLGFIPAK HSTTVEFVTS LTYPEMRIIN KKHQGFIPST
360 370 380 390 400
PAEFRECWLR SEDYAKLIKF MDRYEENHSD IHAFKDAKFD QTRLQKFLRW
410 420 430 440 450
LNSNPCLIPY RLQVFATAKV TFFQYLHDYS YIATFVFTYV FQALMLGSLF
460 470 480 490 500
YNLRNESSEL YSRGSVLSNA IVFTAIQTMS EVDIIFLKKS LFKEHRVQSL
510 520 530 540 550
YHPSAALMGS SLVEFPMRIV VVTMYDIIVY FLSDLKRNAR SFFIFYLFTI
560 570 580 590 600
VITFCMSAVF RFIALLSTTA EIAALIGGIG ALVLIIFCGA VMPVQYIGWW
610 620 630 640 650
FRWIAYANPV NYGYESIMLN EFDGREIPCS LMAPAPDTAP IENNFCLATA
660 670 680 690 700
GRTGTSIVSG YQYLQVVYQY KADFLWRNCG IILGFAIFIL ASSLILANFI
710 720 730 740 750
RYDRESVHIP EFQKRKSYSQ VASSFLIEPQ DKPPSQTEPD NKKVDVSTTL
760 770 780 790 800
STNDNLVLCW RDLNFTVVTK TSKKQILTNV SGYLKKNTLT ALLGENKSGK
810 820 830 840 850
SVLLRILSQR GIAGSVEGEI TLSGLKNPKN LRKRIGYVRK NPLFISEYTV
860 870 880 890 900
RETLRLHAAL RQSKQRSLSE QYAYVEYVID FLGLGEVADF IVGDMGKGLS
910 920 930 940 950
LYHKRLLSIA VELSARPGSI LLLDEPANGL DSQSAWMLVC ILQKLARSGL
960 970 980 990 1000
SILCSVSQPS SRILELFDMM LILDLNGNTV YYDTMGRDLS KLVNYFKRIH
1010 1020 1030 1040 1050
GTNEHSKDTA DFVLHCIQFL KQGPEFDYAG AWASTNTHKQ IIEHVNFIMD
1060 1070 1080 1090 1100
NPELTDDDFP NETRFMTSFF FQIYKISMRN FVAYWRDSSL LRARVAFNIV
1110 1120 1130 1140 1150
AGLIIGFSFY KQGVGVEETQ NKMFSAYMLT VASTSTMNGL QPKFIYFRSI
1160 1170 1180 1190 1200
YEQYEQNTAI YSRTAFIIAF FLVEAVINCC FATLFFFGWY YPSGFYEFNH
1210 1220 1230 1240 1250
NIPFYGGFAW LMLMIFTLYY TTLGIGIATI SPSIGTASII SGTAFVFIQY
1260 1270 1280 1290 1300
FNGMIQLPGV IVGFWKWMDA LSPYKYFLEG MIGGVLHDAP ITCEKFEIHY
1310 1320 1330 1340 1350
VDPPPNYSCG EYFSSFLNSS GHGIVYNPEA YSSCQYCPYK NADELMVGFG
1360 1370 1380 1390
YHYNHKWRNF CIMIGYTAFN LGAAIALYYI IHKTPWKRLA ARFVPD
Length:1,396
Mass (Da):159,319
Last modified:June 1, 2001 - v1
Checksum:iB4CA19755056AD75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAC36905.1.
RefSeqiNP_593995.1. NM_001019421.2.

Genome annotation databases

EnsemblFungiiSPAPB24D3.09c.1; SPAPB24D3.09c.1:pep; SPAPB24D3.09c.
GeneIDi2543363.
KEGGispo:SPAPB24D3.09c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAC36905.1.
RefSeqiNP_593995.1. NM_001019421.2.

3D structure databases

ProteinModelPortaliQ9C0Y5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279785. 12 interactions.

Proteomic databases

MaxQBiQ9C0Y5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAPB24D3.09c.1; SPAPB24D3.09c.1:pep; SPAPB24D3.09c.
GeneIDi2543363.
KEGGispo:SPAPB24D3.09c.

Organism-specific databases

EuPathDBiFungiDB:SPAPB24D3.09c.
PomBaseiSPAPB24D3.09c. pdr1.

Phylogenomic databases

InParanoidiQ9C0Y5.
OMAiPRSANEF.
OrthoDBiEOG7XDBQ6.
PhylomeDBiQ9C0Y5.

Enzyme and pathway databases

ReactomeiR-SPO-1369062. ABC transporters in lipid homeostasis.
R-SPO-265473. Trafficking of dietary sterols.

Miscellaneous databases

NextBioi20804378.
PROiQ9C0Y5.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR027417. P-loop_NTPase.
IPR010929. PDR_CDR_ABC.
[Graphical view]
PfamiPF01061. ABC2_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
PF06422. PDR_CDR. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "A survey of all 11 ABC transporters in fission yeast: two novel ABC transporters are required for red pigment accumulation in a Schizosaccharomyces pombe adenine biosynthetic mutant."
    Iwaki T., Giga-Hama Y., Takegawa K.
    Microbiology 152:2309-2321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION AS AN ABC TRANSPORTER, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiPDR1_SCHPO
AccessioniPrimary (citable) accession number: Q9C0Y5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: June 1, 2001
Last modified: May 11, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.