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Protein

Protein transport protein tip20

Gene

tip20

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Required for protein transport between the Golgi and the endoplasmic reticulum. May contribute to tethering of coatomer-coated retrograde transport vesicles to the ER membrane through interaction with and stabilization of the SNARE complex (By similarity).By similarity

GO - Biological processi

  • double-strand break repair via homologous recombination Source: PomBase
  • Golgi vesicle transport Source: InterPro
  • protein transport Source: UniProtKB-KW

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein tip20
Gene namesi
Name:tip20
ORF Names:pi034, SPBC691.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC691.02c.
PomBaseiSPBC691.02c.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001168521 – 678Protein transport protein tip20Add BLAST678

Proteomic databases

MaxQBiQ9C0W8.
PRIDEiQ9C0W8.

PTM databases

SwissPalmiQ9C0W8.

Interactioni

Subunit structurei

Component of a peripheral membrane protein complex consisting of dsl1, sec39/dsl3 and tip20. Bound to a SNARE complex consisting of ufe1, use1, sec20 and sec22 or ykt6 through direct interaction of tip20 with sec20. Interacts with dsl1, sec39/dsl3 and the cytoplasmic domain of sec20 (By similarity).By similarity

Protein-protein interaction databases

BioGridi277596. 3 interactors.
MINTiMINT-4701966.
STRINGi4896.SPBC691.02c.1.

Structurei

3D structure databases

SMRiQ9C0W8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini99 – 678RINT1/TIP20PROSITE-ProRule annotationAdd BLAST580

Phylogenomic databases

InParanoidiQ9C0W8.
KOiK20474.
OMAiSIEKPEW.
OrthoDBiEOG092C0XZL.
PhylomeDBiQ9C0W8.

Family and domain databases

InterProiView protein in InterPro
IPR007528. RINT1_Tip20.
PANTHERiPTHR13520. PTHR13520. 1 hit.
PfamiView protein in Pfam
PF04437. RINT1_TIP1. 1 hit.
PROSITEiView protein in PROSITE
PS51386. RINT1_TIP20. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9C0W8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSQQLIDFI DSRTRHPYKS DEVEKFQQEV NELQLPDPNS LPILSEEEKR
60 70 80 90 100
QAREDAAFRR SSEGLEDAWL DSAIPADPTP IFRDTVELLC VYQSFVKKSA
110 120 130 140 150
SLDTVANFLD FSTDFSTLST KKDETEIAPD CLHYIAELLF QKKEREVKEK
160 170 180 190 200
WKNELTEKLK TLFNWPAINP NLKESSKFES FFGFVRSIQS FKDSETGLPL
210 220 230 240 250
FMQVYITPYV NQFRYHFMSQ KQTNVLSKPE WFFEFLLKVF RSNRSFYMLM
260 270 280 290 300
RDIKFFPGVP PFFTFINLLN NVAKEKLTHI IKYDDYLVHL VHETLQYSVR
310 320 330 340 350
LEQHFHYTQD PLIIFLFEQN GTYDKWLGLE TQLSLTKLED IKIASDAWEL
360 370 380 390 400
ESDQSDDFSS AVPTKMTVRF RDMIETTFSV LQNLPSLDYQ FNFWRSVQLK
410 420 430 440 450
PMMQYVNWLE AFYESHESSS SIHLPGSLQT DKSKFDIAEV ERMCKLYSNF
460 470 480 490 500
KLLMDWLDDI EDEDVYIRIG HKMGSENYAA FYQVKPRLST LTNGSFRMIL
510 520 530 540 550
RAVSQTLRPL LDNYSDLDTW VIKEQLPGAA LLSTSVSAEI VGFQSRLKEI
560 570 580 590 600
IALLQKLLIG SSQCEAIYQI GTLVESWMIK IVMTHQFSVR GGVQFAMDAM
610 620 630 640 650
QIVLEFSDYP LLKFERLMST VELLSLESGE NKLIKKLIIE INQKNYDFID
660 670
EFFKTKEITL SYEDALGVLY RRVDAWKD
Length:678
Mass (Da):79,407
Last modified:June 1, 2001 - v1
Checksum:iEE5ACAA487F0485E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB004536 Genomic DNA. Translation: BAA21413.1.
AB004537 Genomic DNA. Translation: BAA21414.1.
CU329671 Genomic DNA. Translation: CAC37363.1.
RefSeqiNP_595594.1. NM_001021490.2.

Genome annotation databases

EnsemblFungiiSPBC691.02c.1; SPBC691.02c.1:pep; SPBC691.02c.
GeneIDi2541081.
KEGGispo:SPBC691.02c.

Entry informationi

Entry nameiTIP20_SCHPO
AccessioniPrimary (citable) accession number: Q9C0W8
Secondary accession number(s): O13625, O13626
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: June 1, 2001
Last modified: July 5, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names