Q9C0U6 (XKS1_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Xylulose kinase
Short name=Xylulokinase
EC=2.7.1.17

Gene names

Name:	xks1
ORF Names:	SPCPJ732.02c

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	555 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-xylulose = ADP + D-xylulose 5-phosphate. UniProtKB P42826
Subcellular location	Cytoplasm Ref.2.
Sequence similarities	Belongs to the FGGY kinase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Xylose metabolism
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	D-xylose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW xylulose catabolic process Inferred from sequence orthology. Source: PomBase
Cellular_component	cytosol Inferred from direct assay Ref.2. Source: PomBase nucleus Inferred from direct assay Ref.2. Source: PomBase
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW xylulokinase activity Inferred from sequence orthology. Source: PomBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 555	555	Xylulose kinase		PRO_0000311717

Sequences

	Sequence		Length	Mass (Da)
	Q9C0U6 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 610CE6A309244E01	FASTA	555	61,683
	10 20 30 40 50 60 MFLGLDLSTQ QLKGVVIDES LNVHQEVAVD FDRDLSDYNT IKGVYRNGYE VFAPVCMWLD 70 80 90 100 110 120 AIDLLFERLK ASVDVSKIQA ISGAGQQHAS VFLLKGSKKA LNSLDAKSSL KQQLESLIHP 130 140 150 160 170 180 TSPNWQDAST TKECEELESC IGGAKALADL TGSKAHLRFT GPQIKRFRRL HPETYENTER 190 200 210 220 230 240 IALVSNFLAS VLLQTEAPLD ISDVCGMNLW DIQNEKFDIR LLEEVAGNSK GPDLANKLGT 250 260 270 280 290 300 VEINGAKHLG PIGKYFVKKY GFSPNCQIIP LTGDNPATIL SLPLRPGKDV LLSLGTSTTA 310 320 330 340 350 360 LMATQNYVCS PEYHMFAHPV TQNHYMVMLC YKNGSLAREQ VRNTINEKYN VSDNTSWDRF 370 380 390 400 410 420 NESILNPNIK GAGEKKQLGL FYPQREILPA VGPGTWRFAI QGTELYQVDK DEESWDYPDE 430 440 450 460 470 480 DASAIVESQN LDIRMRITPL LTGIPQPDRV YVVGGASRNE AIVFKISQVL GCDVYRLKHG 490 500 510 520 530 540 GSNACAVGGA IKAAYAMNGK GFTFEEYVNK SWDESKKIEL IMNKPSAQTY EEYGKLLPFL 550 KKAEDIAIQQ SDIRH

References

[1]

"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.

[2]

"ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329672 Genomic DNA. Translation: CAC34988.1.
RefSeq	NP_587930.1. NM_001022921.2.
3D structure databases
ProteinModelPortal	Q9C0U6.
ModBase	Search...
Protein-protein interaction databases
STRING	4896.SPCPJ732.02c-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPCPJ732.02c.1; SPCPJ732.02c.1:pep; SPCPJ732.02c.
GeneID	2539441.
KEGG	spo:SPCPJ732.02c.
Organism-specific databases
PomBase	SPCPJ732.02c.
Phylogenomic databases
eggNOG	COG1070.
HOGENOM	HOG000174850.
KO	K00854.
OMA	SYSPIDY.
OrthoDB	EOG4578GH.
Family and domain databases
InterPro	IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. [Graphical view]
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
PROSITE	PS00933. FGGY_KINASES_1. False negative. PS00445. FGGY_KINASES_2. False negative. [Graphical view]
ProtoNet	Search...
Other
NextBio	20800603.

Entry information

Entry name

XKS1_SCHPO

Accession

Primary (citable) accession number: Q9C0U6

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 13, 2007
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program