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Unreviewed, UniProtKB/TrEMBL Q9C001 (Q9C001_HUMAN)

Last modified January 19, 2010. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Interleukin-2 EMBL AAG53575.1
OrganismHomo sapiens (Human) EMBL AAG53575.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length150 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level.

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Ontologies

Gene Ontology (GO)
   Biological processactivation of protein kinase C activity by G-protein coupled receptor protein signaling pathway

Inferred from electronic annotation. Source: Compara

elevation of cytosolic calcium ion concentration

Inferred from electronic annotation. Source: Compara

immune response

Inferred from electronic annotation. Source: InterPro

negative regulation of heart contraction

Inferred from electronic annotation. Source: Compara

negative regulation of inflammatory response

Inferred from electronic annotation. Source: Compara

negative regulation of lymphocyte proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of protein amino acid phosphorylation

Inferred from electronic annotation. Source: Compara

positive regulation of activated T cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of immunoglobulin secretion

Inferred from electronic annotation. Source: Compara

positive regulation of isotype switching to IgG isotypes

Inferred from electronic annotation. Source: Compara

positive regulation of regulatory T cell differentiation

Inferred from electronic annotation. Source: Compara

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

positive regulation of tyrosine phosphorylation of Stat5 protein

Inferred from electronic annotation. Source: Compara

regulation of T cell homeostatic proliferation

Inferred from electronic annotation. Source: Compara

   Cellular componentextracellular space

Inferred from electronic annotation. Source: Compara

   Molecular functioncarbohydrate binding

Inferred from electronic annotation. Source: Compara

cytokine activity

Inferred from electronic annotation. Source: Compara

glycosphingolipid binding

Inferred from electronic annotation. Source: Compara

growth factor activity

Inferred from electronic annotation. Source: InterPro

interleukin-2 receptor binding

Inferred from electronic annotation. Source: Compara

kappa-type opioid receptor binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue1501 EMBL AAG53575.1

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Sequences

Sequence LengthMass (Da)Tools
Q9C001-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: BF25860F8436ACE5

FASTA15017,312
        10         20         30         40         50         60 
MYRMQLLSCI ALSLALVTNS APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML 

        70         80         90        100        110        120 
TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE 

       130        140        150 
TTFMCEYADE TATIVEFLNR WITFCQSIIS

« Hide

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References

[1]"Allelic selection of human IL-2 gene."
Matesanz F., Delgado C., Fresno M., Alcina A.
Eur. J. Immunol. 30:3516-3521(2000) [PubMed: 11093171] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF228636 mRNA. Translation: AAG53575.1.
IPIIPI00003099.
UniGeneHs.89679

3D structure databases

HSSPHSSP built from PDB template 1IRL based on UniProtKB P60568.
SMRQ9C001. Positions 25-150.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ9C001.

Genome annotation databases

EnsemblENST00000226730; ENSP00000226730; ENSG00000109471; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:6001. IL2.

Phylogenomic databases

HOVERGENQ9C001.
PhylomeDBQ9C001.

Gene expression databases

ArrayExpressQ9C001.
BgeeQ9C001.

Family and domain databases

InterProIPR009079. 4_helix_cytokine-like_core.
IPR000779. Interleukin-2.
[Graphical view]
PANTHERPTHR11443. Interleukin-2. 1 hit.
PfamPF00715. IL2. 1 hit.
[Graphical view]
PRINTSPR00265. INTERLEUKIN2.
ProDomPD003649. Interleukin-2. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTSM00189. IL2. 1 hit.
[Graphical view]
PROSITEPS00424. INTERLEUKIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ9C001_HUMAN
AccessionPrimary (citable) accession number: Q9C001
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: January 19, 2010
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information