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Q9BZX2

- UCK2_HUMAN

UniProt

Q9BZX2 - UCK2_HUMAN

Protein

Uridine-cytidine kinase 2

Gene

UCK2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 123 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

    Catalytic activityi

    ATP + uridine = ADP + UMP.
    ATP + cytidine = ADP + CMP.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei84 – 841Substrate
    Binding sitei112 – 1121Substrate
    Binding sitei117 – 1171Substrate
    Binding sitei166 – 1661Substrate
    Binding sitei176 – 1761Substrate
    Binding sitei184 – 1841Substrate
    Binding sitei213 – 2131ATP

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi27 – 359ATP

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. nucleoside kinase activity Source: Reactome
    3. uridine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular response to oxygen levels Source: Ensembl
    2. CTP salvage Source: UniProtKB-UniPathway
    3. feeding behavior Source: Ensembl
    4. nucleobase-containing small molecule metabolic process Source: Reactome
    5. pyrimidine nucleobase metabolic process Source: Reactome
    6. pyrimidine nucleoside salvage Source: Reactome
    7. response to axon injury Source: Ensembl
    8. small molecule metabolic process Source: Reactome
    9. UMP salvage Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMetaCyc:HS07003-MONOMER.
    BRENDAi2.7.1.48. 2681.
    ReactomeiREACT_655. Pyrimidine salvage reactions.
    SABIO-RKQ9BZX2.
    UniPathwayiUPA00574; UER00637.
    UPA00579; UER00640.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uridine-cytidine kinase 2 (EC:2.7.1.48)
    Short name:
    UCK 2
    Alternative name(s):
    Cytidine monophosphokinase 2
    Testis-specific protein TSA903
    Uridine monophosphokinase 2
    Gene namesi
    Name:UCK2
    Synonyms:UMPK
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 1

    Organism-specific databases

    HGNCiHGNC:12562. UCK2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Reactome
    2. intracellular membrane-bounded organelle Source: Ensembl

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA362.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 261260Uridine-cytidine kinase 2PRO_0000164455Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine1 Publication
    Modified residuei254 – 2541Phosphoserine1 Publication

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ9BZX2.
    PaxDbiQ9BZX2.
    PeptideAtlasiQ9BZX2.
    PRIDEiQ9BZX2.

    PTM databases

    PhosphoSiteiQ9BZX2.

    Expressioni

    Tissue specificityi

    According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific.1 Publication

    Gene expression databases

    ArrayExpressiQ9BZX2.
    BgeeiQ9BZX2.
    CleanExiHS_UCK2.
    GenevestigatoriQ9BZX2.

    Organism-specific databases

    HPAiHPA051286.

    Interactioni

    Subunit structurei

    Homotetramer.2 Publications

    Protein-protein interaction databases

    BioGridi113217. 4 interactions.
    IntActiQ9BZX2. 1 interaction.
    STRINGi9606.ENSP00000356853.

    Structurei

    Secondary structure

    1
    261
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi21 – 266
    Helixi33 – 4311
    Helixi46 – 483
    Helixi51 – 533
    Beta strandi55 – 606
    Helixi61 – 644
    Helixi70 – 778
    Helixi86 – 883
    Helixi91 – 10212
    Beta strandi107 – 1137
    Turni114 – 1174
    Beta strandi118 – 1269
    Beta strandi130 – 1356
    Turni137 – 1404
    Helixi143 – 1486
    Beta strandi150 – 1567
    Helixi159 – 17315
    Helixi178 – 18710
    Helixi189 – 1968
    Helixi198 – 2036
    Beta strandi205 – 2095
    Helixi211 – 2133
    Helixi215 – 23016

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1UDWX-ray2.60A/B1-250[»]
    1UEIX-ray2.60A/B1-250[»]
    1UEJX-ray2.61A/B1-250[»]
    1UFQX-ray2.50A/B/C/D1-250[»]
    1UJ2X-ray1.80A/B1-250[»]
    1XRJX-ray2.00A/B1-261[»]
    ProteinModelPortaliQ9BZX2.
    SMRiQ9BZX2. Positions 19-231.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9BZX2.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the uridine kinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0572.
    HOGENOMiHOG000262756.
    HOVERGENiHBG023339.
    InParanoidiQ9BZX2.
    KOiK00876.
    OMAiHTSIARD.
    OrthoDBiEOG7Q8CP2.
    PhylomeDBiQ9BZX2.
    TreeFamiTF316686.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR006083. PRK/URK.
    IPR000764. Uridine_kinase_like.
    [Graphical view]
    PfamiPF00485. PRK. 1 hit.
    [Graphical view]
    PRINTSiPR00988. URIDINKINASE.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00235. udk. 1 hit.

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9BZX2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD    50
    YRQKQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE 100
    ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ 150
    MKLFVDTDAD TRLSRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT 200
    KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK 250
    RQASESSSRP H 261
    Length:261
    Mass (Da):29,299
    Last modified:June 1, 2001 - v1
    Checksum:i71791346F091EBFD
    GO
    Isoform 2 (identifier: Q9BZX2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-150: Missing.

    Show »
    Length:111
    Mass (Da):12,587
    Checksum:iE6688B1B86F432A9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti202 – 2021K → Q in BAA11349. (PubMed:8812458)Curated
    Sequence conflicti222 – 2221V → E in BAA11349. (PubMed:8812458)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 150150Missing in isoform 2. 3 PublicationsVSP_014262Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78335 mRNA. Translation: BAA11349.1.
    AF236637 mRNA. Translation: AAK14053.1.
    BT006860 mRNA. Translation: AAP35506.1.
    CR456857 mRNA. Translation: CAG33138.1.
    AL451074, AL358115 Genomic DNA. Translation: CAH74066.1.
    AL358115, AL451074 Genomic DNA. Translation: CAI15121.1.
    BC002906 mRNA. Translation: AAH02906.2.
    AB062451 mRNA. Translation: BAB56162.1.
    CCDSiCCDS1252.1. [Q9BZX2-1]
    RefSeqiNP_036606.2. NM_012474.4. [Q9BZX2-1]
    UniGeneiHs.458360.

    Genome annotation databases

    EnsembliENST00000367879; ENSP00000356853; ENSG00000143179. [Q9BZX2-1]
    ENST00000469256; ENSP00000476692; ENSG00000143179. [Q9BZX2-2]
    ENST00000470820; ENSP00000476327; ENSG00000143179. [Q9BZX2-2]
    GeneIDi7371.
    KEGGihsa:7371.
    UCSCiuc001gdp.3. human. [Q9BZX2-1]
    uc010plb.2. human. [Q9BZX2-2]

    Polymorphism databases

    DMDMi20455356.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78335 mRNA. Translation: BAA11349.1 .
    AF236637 mRNA. Translation: AAK14053.1 .
    BT006860 mRNA. Translation: AAP35506.1 .
    CR456857 mRNA. Translation: CAG33138.1 .
    AL451074 , AL358115 Genomic DNA. Translation: CAH74066.1 .
    AL358115 , AL451074 Genomic DNA. Translation: CAI15121.1 .
    BC002906 mRNA. Translation: AAH02906.2 .
    AB062451 mRNA. Translation: BAB56162.1 .
    CCDSi CCDS1252.1. [Q9BZX2-1 ]
    RefSeqi NP_036606.2. NM_012474.4. [Q9BZX2-1 ]
    UniGenei Hs.458360.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1UDW X-ray 2.60 A/B 1-250 [» ]
    1UEI X-ray 2.60 A/B 1-250 [» ]
    1UEJ X-ray 2.61 A/B 1-250 [» ]
    1UFQ X-ray 2.50 A/B/C/D 1-250 [» ]
    1UJ2 X-ray 1.80 A/B 1-250 [» ]
    1XRJ X-ray 2.00 A/B 1-261 [» ]
    ProteinModelPortali Q9BZX2.
    SMRi Q9BZX2. Positions 19-231.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 113217. 4 interactions.
    IntActi Q9BZX2. 1 interaction.
    STRINGi 9606.ENSP00000356853.

    Chemistry

    ChEMBLi CHEMBL2469.

    PTM databases

    PhosphoSitei Q9BZX2.

    Polymorphism databases

    DMDMi 20455356.

    Proteomic databases

    MaxQBi Q9BZX2.
    PaxDbi Q9BZX2.
    PeptideAtlasi Q9BZX2.
    PRIDEi Q9BZX2.

    Protocols and materials databases

    DNASUi 7371.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000367879 ; ENSP00000356853 ; ENSG00000143179 . [Q9BZX2-1 ]
    ENST00000469256 ; ENSP00000476692 ; ENSG00000143179 . [Q9BZX2-2 ]
    ENST00000470820 ; ENSP00000476327 ; ENSG00000143179 . [Q9BZX2-2 ]
    GeneIDi 7371.
    KEGGi hsa:7371.
    UCSCi uc001gdp.3. human. [Q9BZX2-1 ]
    uc010plb.2. human. [Q9BZX2-2 ]

    Organism-specific databases

    CTDi 7371.
    GeneCardsi GC01P165796.
    HGNCi HGNC:12562. UCK2.
    HPAi HPA051286.
    MIMi 609329. gene.
    neXtProti NX_Q9BZX2.
    PharmGKBi PA362.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0572.
    HOGENOMi HOG000262756.
    HOVERGENi HBG023339.
    InParanoidi Q9BZX2.
    KOi K00876.
    OMAi HTSIARD.
    OrthoDBi EOG7Q8CP2.
    PhylomeDBi Q9BZX2.
    TreeFami TF316686.

    Enzyme and pathway databases

    UniPathwayi UPA00574 ; UER00637 .
    UPA00579 ; UER00640 .
    BioCyci MetaCyc:HS07003-MONOMER.
    BRENDAi 2.7.1.48. 2681.
    Reactomei REACT_655. Pyrimidine salvage reactions.
    SABIO-RK Q9BZX2.

    Miscellaneous databases

    ChiTaRSi UCK2. human.
    EvolutionaryTracei Q9BZX2.
    GeneWikii UCK2.
    GenomeRNAii 7371.
    NextBioi 28862.
    PROi Q9BZX2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9BZX2.
    Bgeei Q9BZX2.
    CleanExi HS_UCK2.
    Genevestigatori Q9BZX2.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR006083. PRK/URK.
    IPR000764. Uridine_kinase_like.
    [Graphical view ]
    Pfami PF00485. PRK. 1 hit.
    [Graphical view ]
    PRINTSi PR00988. URIDINKINASE.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00235. udk. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method."
      Ozaki K., Kuroki T., Hayashi S., Nakamura Y.
      Genomics 36:316-319(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
    2. "Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases."
      Van Rompay A.R., Norda A., Linden K., Johansson M., Karlsson A.
      Mol. Pharmacol. 59:1181-1186(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), CHARACTERIZATION.
    3. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    4. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
      Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    5. "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
      , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
      Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Lung.
    7. "Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells."
      Koizumi K., Shimamoto Y., Azuma A., Wataya Y., Matsuda A., Sasaki T., Fukushima M.
      Int. J. Mol. Med. 8:273-278(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 15-261 (ISOFORM 1).
      Tissue: Fibrosarcoma.
    8. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H., Olsen J.V., Bairlein M., Gnad F., Oppermann F.S., Korner R., Greff Z., Keri G., Stemmann O., Mann M.
      Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].
    10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-254, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    13. "Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase."
      Suzuki N.N., Koizumi K., Fukushima M., Matsuda A., Inagaki F.
      Structure 12:751-764(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 1-250 IN COMPLEXES WITH ADP; CYTIDINE; CMP; CTP AND UTP, SUBUNIT.
    14. "Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative."
      Appleby T.C., Larson G., Cheney I.W., Walker H., Wu J.Z., Zhong W., Hong Z., Yao N.
      Acta Crystallogr. D 61:278-284(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH ADP AND CMP, SUBUNIT.

    Entry informationi

    Entry nameiUCK2_HUMAN
    AccessioniPrimary (citable) accession number: Q9BZX2
    Secondary accession number(s): Q5VV91
    , Q7KZV3, Q92528, Q96KG5, Q9BU42
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 2, 2002
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 123 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 1
      Human chromosome 1: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    4. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3