Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein Niban

Gene

FAM129A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Stress response, Translation regulation

Enzyme and pathway databases

SIGNORiQ9BZQ8.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein Niban
Alternative name(s):
Cell growth-inhibiting gene 39 protein
Protein FAM129A
Gene namesi
Name:FAM129A
Synonyms:C1orf24, NIBAN
ORF Names:GIG39
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:16784. FAM129A.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • extracellular exosome Source: UniProtKB
  • membrane Source: UniProtKB
  • plasma membrane Source: HPA
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162385951.

Polymorphism and mutation databases

DMDMi22256936.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 928927Protein NibanPRO_0000213120Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycine1 Publication
Modified residuei579 – 5791PhosphoserineCombined sources
Modified residuei582 – 5821PhosphoserineCombined sources
Modified residuei596 – 5961PhosphoserineCombined sources
Modified residuei602 – 6021PhosphoserineCombined sources
Modified residuei646 – 6461PhosphoserineCombined sources
Modified residuei708 – 7081PhosphoserineCombined sources
Modified residuei926 – 9261PhosphoserineCombined sources

Keywords - PTMi

Lipoprotein, Myristate, Phosphoprotein

Proteomic databases

EPDiQ9BZQ8.
MaxQBiQ9BZQ8.
PaxDbiQ9BZQ8.
PeptideAtlasiQ9BZQ8.
PRIDEiQ9BZQ8.

PTM databases

iPTMnetiQ9BZQ8.
PhosphoSiteiQ9BZQ8.

Expressioni

Tissue specificityi

Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney.2 Publications

Gene expression databases

BgeeiQ9BZQ8.
CleanExiHS_FAM129A.
ExpressionAtlasiQ9BZQ8. baseline and differential.
GenevisibleiQ9BZQ8. HS.

Organism-specific databases

HPAiHPA028172.
HPA028231.
HPA028657.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
AKT1P317492EBI-6916466,EBI-296087
FHL2Q141923EBI-6916466,EBI-701903
NPM1P067487EBI-6916466,EBI-78579

Protein-protein interaction databases

BioGridi125515. 5 interactions.
IntActiQ9BZQ8. 3 interactions.
MINTiMINT-6943981.
STRINGi9606.ENSP00000356481.

Structurei

3D structure databases

ProteinModelPortaliQ9BZQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi683 – 864182Glu-richAdd
BLAST

Sequence similaritiesi

Belongs to the Niban family.Curated

Phylogenomic databases

eggNOGiENOG410IFR1. Eukaryota.
ENOG41102BB. LUCA.
GeneTreeiENSGT00530000063284.
HOVERGENiHBG108186.
InParanoidiQ9BZQ8.
OMAiEDEYNLL.
OrthoDBiEOG7GN2MC.
PhylomeDBiQ9BZQ8.
TreeFamiTF333351.

Family and domain databases

InterProiIPR026088. Niban-like.
[Graphical view]
PANTHERiPTHR14392. PTHR14392. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BZQ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGSASSQLD EGKCAYIRGK TEAAIKNFSP YYSRQYSVAF CNHVRTEVEQ
60 70 80 90 100
QRDLTSQFLK TKPPLAPGTI LYEAELSQFS EDIKKWKERY VVVKNDYAVE
110 120 130 140 150
SYENKEAYQR GAAPKCRILP AGGKVLTSED EYNLLSDRHF PDPLASSEKE
160 170 180 190 200
NTQPFVVLPK EFPVYLWQPF FRHGYFCFHE AADQKRFSAL LSDCVRHLNH
210 220 230 240 250
DYMKQMTFEA QAFLEAVQFF RQEKGHYGSW EMITGDEIQI LSNLVMEELL
260 270 280 290 300
PTLQTDLLPK MKGKKNDRKR TWLGLLEEAY TLVQHQVSEG LSALKEECRA
310 320 330 340 350
LTKGLEGTIR SDMDQIVNSK NYLIGKIKAM VAQPAEKSCL ESVQPFLASI
360 370 380 390 400
LEELMGPVSS GFSEVRVLFE KEVNEVSQNF QTTKDSVQLK EHLDRLMNLP
410 420 430 440 450
LHSVKMEPCY TKVNLLHERL QDLKSRFRFP HIDLVVQRTQ NYMQELMENA
460 470 480 490 500
VFTFEQLLSP HLQGEASKTA VAIEKVKLRV LKQYDYDSST IRKKIFQEAL
510 520 530 540 550
VQITLPTVQK ALASTCKPEL QKYEQFIFAD HTNMIHVENV YEEILHQILL
560 570 580 590 600
DETLKVIKEA AILKKHNLFE DNMALPSESV SSLTDLKPPT GSNQASPARR
610 620 630 640 650
ASAILPGVLG SETLSNEVFQ ESEEEKQPEV PSSLAKGESL SLPGPSPPPD
660 670 680 690 700
GTEQVIISRV DDPVVNPVAT EDTAGLPGTC SSELEFGGTL EDEEPAQEEP
710 720 730 740 750
EPITASGSLK ALRKLLTASV EVPVDSAPVM EEDTNGESHV PQENEEEEEK
760 770 780 790 800
EPSQAAAIHP DNCEESEVSE REAQPPCPEA HGEELGGFPE VGSPASPPAS
810 820 830 840 850
GGLTEEPLGP MEGELPGEAC TLTAHEGRGG KCTEEGDASQ QEGCTLGSDP
860 870 880 890 900
ICLSESQVSE EQEEMGGQSS AAQATASVNA EEIKVARIHE CQWVVEDAPN
910 920
PDVLLSHKDD VKEGEGGQES FPELPSEE
Length:928
Mass (Da):103,135
Last modified:June 1, 2001 - v1
Checksum:i93717F41336488FE
GO

Sequence cautioni

The sequence BAB17230.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti27 – 271N → D in AAT52218 (Ref. 4) Curated
Sequence conflicti106 – 1061E → G in BAB14079 (PubMed:14702039).Curated
Sequence conflicti201 – 2011D → E in BAB14079 (PubMed:14702039).Curated
Sequence conflicti609 – 6091L → P in BAB84965 (Ref. 7) Curated
Sequence conflicti858 – 8581V → D in BAB14079 (PubMed:14702039).Curated
Sequence conflicti863 – 8631E → D in BAB14079 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti633 – 6331S → L.
Corresponds to variant rs12750174 [ dbSNP | Ensembl ].
VAR_053533
Natural varianti692 – 6921D → N.1 Publication
Corresponds to variant rs35704242 [ dbSNP | Ensembl ].
VAR_053534
Natural varianti720 – 7201V → M.
Corresponds to variant rs17313374 [ dbSNP | Ensembl ].
VAR_053535
Natural varianti830 – 8301G → S.
Corresponds to variant rs35601690 [ dbSNP | Ensembl ].
VAR_053536

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050477 mRNA. Translation: BAB17230.1. Different initiation.
AF288391 mRNA. Translation: AAG60611.1.
AK022527 mRNA. Translation: BAB14079.1.
AY550972 mRNA. Translation: AAT52218.1.
AL109865
, AL096819, AL109956, AL136086 Genomic DNA. Translation: CAI17848.1.
AL109956
, AL096819, AL109865, AL136086 Genomic DNA. Translation: CAI17877.1.
AL096819
, AL109865, AL109956, AL136086 Genomic DNA. Translation: CAI21739.1.
BC030531 mRNA. Translation: AAH30531.1.
AK074139 mRNA. Translation: BAB84965.1.
CCDSiCCDS1364.1.
RefSeqiNP_443198.1. NM_052966.3.
UniGeneiHs.518662.

Genome annotation databases

EnsembliENST00000367511; ENSP00000356481; ENSG00000135842.
GeneIDi116496.
KEGGihsa:116496.
UCSCiuc001gra.5. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB050477 mRNA. Translation: BAB17230.1. Different initiation.
AF288391 mRNA. Translation: AAG60611.1.
AK022527 mRNA. Translation: BAB14079.1.
AY550972 mRNA. Translation: AAT52218.1.
AL109865
, AL096819, AL109956, AL136086 Genomic DNA. Translation: CAI17848.1.
AL109956
, AL096819, AL109865, AL136086 Genomic DNA. Translation: CAI17877.1.
AL096819
, AL109865, AL109956, AL136086 Genomic DNA. Translation: CAI21739.1.
BC030531 mRNA. Translation: AAH30531.1.
AK074139 mRNA. Translation: BAB84965.1.
CCDSiCCDS1364.1.
RefSeqiNP_443198.1. NM_052966.3.
UniGeneiHs.518662.

3D structure databases

ProteinModelPortaliQ9BZQ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125515. 5 interactions.
IntActiQ9BZQ8. 3 interactions.
MINTiMINT-6943981.
STRINGi9606.ENSP00000356481.

PTM databases

iPTMnetiQ9BZQ8.
PhosphoSiteiQ9BZQ8.

Polymorphism and mutation databases

DMDMi22256936.

Proteomic databases

EPDiQ9BZQ8.
MaxQBiQ9BZQ8.
PaxDbiQ9BZQ8.
PeptideAtlasiQ9BZQ8.
PRIDEiQ9BZQ8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000367511; ENSP00000356481; ENSG00000135842.
GeneIDi116496.
KEGGihsa:116496.
UCSCiuc001gra.5. human.

Organism-specific databases

CTDi116496.
GeneCardsiFAM129A.
HGNCiHGNC:16784. FAM129A.
HPAiHPA028172.
HPA028231.
HPA028657.
neXtProtiNX_Q9BZQ8.
PharmGKBiPA162385951.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFR1. Eukaryota.
ENOG41102BB. LUCA.
GeneTreeiENSGT00530000063284.
HOVERGENiHBG108186.
InParanoidiQ9BZQ8.
OMAiEDEYNLL.
OrthoDBiEOG7GN2MC.
PhylomeDBiQ9BZQ8.
TreeFamiTF333351.

Enzyme and pathway databases

SIGNORiQ9BZQ8.

Miscellaneous databases

ChiTaRSiFAM129A. human.
GeneWikiiFAM129A.
GenomeRNAii116496.
PROiQ9BZQ8.

Gene expression databases

BgeeiQ9BZQ8.
CleanExiHS_FAM129A.
ExpressionAtlasiQ9BZQ8. baseline and differential.
GenevisibleiQ9BZQ8. HS.

Family and domain databases

InterProiIPR026088. Niban-like.
[Graphical view]
PANTHERiPTHR14392. PTHR14392. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A novel gene 'Niban' upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach."
    Majima S., Kajino K., Fukuda T., Otsuka F., Hino O.
    Jpn. J. Cancer Res. 91:869-874(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
    Tissue: Renal cell carcinoma.
  2. "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus."
    Sood R., Bonner T.I., Malakowska I., Stephan D.A., Robbins C.M., Connors T.D., Morgenbesser S.D., Su K., Faruque M.U., Pinkett H., Graham C., Baxevanis A.D., Klinger K.W., Landes G.M., Trent J.M., Carpten J.D.
    Genomics 73:211-222(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Teratocarcinoma.
  4. "Identification of a human cell growth inhibiting gene."
    Kim J.W.
    Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Leukocyte.
  7. "The nucleotide sequence of a long cDNA clone isolated from human spleen."
    Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 522-928, VARIANT ASN-692.
    Tissue: Spleen.
  8. "A novel tumor marker, Niban, is expressed in subsets of thyroid tumors and Hashimoto's thyroiditis."
    Matsumoto F., Fujii H., Abe M., Kajino K., Kobayashi T., Matsumoto T., Ikeda K., Hino O.
    Hum. Pathol. 37:1592-1600(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-579; SER-596; SER-602; SER-646 AND SER-926, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-602 AND SER-926, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-582; SER-602 AND SER-708, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  13. "Multifunctional reagents for quantitative proteome-wide analysis of protein modification in human cells and dynamic profiling of protein lipidation during vertebrate development."
    Broncel M., Serwa R.A., Ciepla P., Krause E., Dallman M.J., Magee A.I., Tate E.W.
    Angew. Chem. Int. Ed. 54:5948-5951(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: MYRISTOYLATION AT GLY-2, CLEAVAGE OF INITIATOR METHIONINE, IDENTIFICATION BY MASS SPECTROMETRY.

Entry informationi

Entry nameiNIBAN_HUMAN
AccessioniPrimary (citable) accession number: Q9BZQ8
Secondary accession number(s): Q2TTR2
, Q5TEM8, Q8TEI5, Q9H593, Q9H9Y8, Q9HCB9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 13, 2002
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

'Niban' means 'second' in Japanese.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.