Q9BZP3 (CR002_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative uncharacterized protein LINC00470

Gene names

Name:	LINC00470
Synonyms:	C18orf2

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	86 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Tissue specificity	Retina-specific. Ref.1
Caution	Product of a dubious CDS prediction. May be a non-coding RNA.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9BZP3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9BZP3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-22: Missing.

Isoform 3 (identifier: Q9BZP3-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-23: MVRHPYSVQTQLSTEAKAIWRSM → MQCLYFILILKGYFHQQHHTLLITIALCFLQ
     62-86: CNCPIIGEIVISCYWLFEIPPLISE → ETQKCIQKPLHEK

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 86	86	Putative uncharacterized protein LINC00470		PRO_0000329448
Natural variations
	Alternative sequence	1 – 23	23	MVRHP…IWRSM → MQCLYFILILKGYFHQQHHT LLITIALCFLQ in isoform 3.		VSP_032987
	Alternative sequence	1 – 22	22	Missing in isoform 2.		VSP_032988
	Alternative sequence	62 – 86	25	CNCPI…PLISE → ETQKCIQKPLHEK in isoform 3.		VSP_032989

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: F36D86CAC6466992	FASTA	86	9,646
	10 20 30 40 50 60 MVRHPYSVQT QLSTEAKAIW RSMQQQETNL LANLTTNDAR DNSKDFQNSK VGAAATSRDE 70 80 GCNCPIIGEI VISCYWLFEI PPLISE
	Isoform 2 [UniParc]. Checksum: C168EF9E8B863957	FASTA	64	7,075
	10 20 30 40 50 60 MQQQETNLLA NLTTNDARDN SKDFQNSKVG AAATSRDEGC NCPIIGEIVI SCYWLFEIPP LISE
	Isoform 3 [UniParc]. Checksum: 5162CA14CED467B5	FASTA	82	9,406
	10 20 30 40 50 60 MQCLYFILIL KGYFHQQHHT LLITIALCFL QQQQETNLLA NLTTNDARDN SKDFQNSKVG 70 80 AAATSRDEGE TQKCIQKPLH EK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"EST mining of the UniGene dataset to identify retina-specific genes." Stoehr H., Mah N., Schulz H.L., Gehrig A., Froehlich S., Weber B.H.F. Cytogenet. Cell Genet. 91:267-277(2000) [PubMed: 11173868] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), TISSUE SPECIFICITY. Tissue: Retina.
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF295726 mRNA. Translation: AAK13319.1. AF295728 mRNA. Translation: AAK13320.1. AF295729 mRNA. Translation: AAK13321.1. CH471113 Genomic DNA. Translation: EAX01703.1. CH471113 Genomic DNA. Translation: EAX01704.1.
IPI	IPI00289169. IPI00889719. IPI00889778.
UniGene	Hs.541165.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9BZP3.
Proteomic databases
PRIDE	Q9BZP3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000269201; ENSP00000269201; ENSG00000132204.
Organism-specific databases
GeneCards	GC18M001268.
HGNC	HGNC:1225. LINC00470.
HPA	HPA041046.
neXtProt	NX_Q9BZP3.
GenAtlas	Search...
Phylogenomic databases
GeneTree	ENSGT00390000004638.
InParanoid	Q9BZP3.
OrthoDB	EOG4HMJBZ.
Gene expression databases
ArrayExpress	Q9BZP3.
Bgee	Q9BZP3.
CleanEx	HS_C18orf2.
Genevestigator	Q9BZP3.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CR002_HUMAN

Accession

Primary (citable) accession number: Q9BZP3
Secondary accession number(s): Q9BZP2, Q9BZP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.