Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9BZL1

- UBL5_HUMAN

UniProt

Q9BZL1 - UBL5_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Ubiquitin-like protein 5

Gene

UBL5

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-like protein 5
Gene namesi
Name:UBL5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 19

Organism-specific databases

HGNCiHGNC:13736. UBL5.

Subcellular locationi

Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37805.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7373Ubiquitin-like protein 5PRO_0000114866Add
BLAST

Proteomic databases

MaxQBiQ9BZL1.
PaxDbiQ9BZL1.
PeptideAtlasiQ9BZL1.
PRIDEiQ9BZL1.

PTM databases

PhosphoSiteiQ9BZL1.

Expressioni

Tissue specificityi

Ubiquitous. Highest level of expression in heart, skeletal muscle, kidney, liver, iris and lymphoblasts.1 Publication

Gene expression databases

BgeeiQ9BZL1.
CleanExiHS_UBL5.
ExpressionAtlasiQ9BZL1. baseline and differential.
GenevestigatoriQ9BZL1.

Interactioni

Subunit structurei

Interacts with CLK1, CLK3 and CLK4.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
WDR83Q9BRX92EBI-607755,EBI-7705033

Protein-protein interaction databases

BioGridi121872. 13 interactions.
IntActiQ9BZL1. 4 interactions.
MINTiMINT-4714927.
STRINGi9606.ENSP00000351492.

Structurei

Secondary structure

1
73
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi2 – 87
Turni9 – 113
Beta strandi12 – 187
Helixi24 – 329
Beta strandi39 – 4810
Beta strandi64 – 718

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1P0RNMR-A1-73[»]
4PYUX-ray2.00A/B/G/K/O/S1-73[»]
ProteinModelPortaliQ9BZL1.
SMRiQ9BZL1. Positions 1-73.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9BZL1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7373Ubiquitin-likeAdd
BLAST

Sequence similaritiesi

Contains 1 ubiquitin-like domain.Curated

Phylogenomic databases

eggNOGiNOG326610.
GeneTreeiENSGT00390000001945.
HOVERGENiHBG055994.
InParanoidiQ9BZL1.
KOiK13113.
OMAiRFIMILA.
OrthoDBiEOG72ZCHN.
PhylomeDBiQ9BZL1.

Family and domain databases

InterProiIPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view]
PfamiPF00240. ubiquitin. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9BZL1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIEVVCNDRL GKKVRVKCNT DDTIGDLKKL IAAQTGTRWN KIVLKKWYTI
60 70
FKDHVSLGDY EIHDGMNLEL YYQ
Length:73
Mass (Da):8,547
Last modified:June 1, 2001 - v1
Checksum:iD68BC941536AA39F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF313915 mRNA. Translation: AAK14178.1.
BT007355 mRNA. Translation: AAP36019.1.
BC007053 mRNA. Translation: AAH07053.1.
BC110839 mRNA. Translation: AAI10840.1.
CCDSiCCDS12219.1.
RefSeqiNP_001041706.1. NM_001048241.2.
NP_077268.1. NM_024292.3.
UniGeneiHs.534477.

Genome annotation databases

EnsembliENST00000358666; ENSP00000351492; ENSG00000198258.
ENST00000586895; ENSP00000468656; ENSG00000198258.
ENST00000590068; ENSP00000466910; ENSG00000198258.
GeneIDi59286.
KEGGihsa:59286.
UCSCiuc002mmi.2. human.

Polymorphism databases

DMDMi52082771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF313915 mRNA. Translation: AAK14178.1 .
BT007355 mRNA. Translation: AAP36019.1 .
BC007053 mRNA. Translation: AAH07053.1 .
BC110839 mRNA. Translation: AAI10840.1 .
CCDSi CCDS12219.1.
RefSeqi NP_001041706.1. NM_001048241.2.
NP_077268.1. NM_024292.3.
UniGenei Hs.534477.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1P0R NMR - A 1-73 [» ]
4PYU X-ray 2.00 A/B/G/K/O/S 1-73 [» ]
ProteinModelPortali Q9BZL1.
SMRi Q9BZL1. Positions 1-73.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 121872. 13 interactions.
IntActi Q9BZL1. 4 interactions.
MINTi MINT-4714927.
STRINGi 9606.ENSP00000351492.

PTM databases

PhosphoSitei Q9BZL1.

Polymorphism databases

DMDMi 52082771.

Proteomic databases

MaxQBi Q9BZL1.
PaxDbi Q9BZL1.
PeptideAtlasi Q9BZL1.
PRIDEi Q9BZL1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000358666 ; ENSP00000351492 ; ENSG00000198258 .
ENST00000586895 ; ENSP00000468656 ; ENSG00000198258 .
ENST00000590068 ; ENSP00000466910 ; ENSG00000198258 .
GeneIDi 59286.
KEGGi hsa:59286.
UCSCi uc002mmi.2. human.

Organism-specific databases

CTDi 59286.
GeneCardsi GC19P009938.
HGNCi HGNC:13736. UBL5.
MIMi 606849. gene.
neXtProti NX_Q9BZL1.
PharmGKBi PA37805.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG326610.
GeneTreei ENSGT00390000001945.
HOVERGENi HBG055994.
InParanoidi Q9BZL1.
KOi K13113.
OMAi RFIMILA.
OrthoDBi EOG72ZCHN.
PhylomeDBi Q9BZL1.

Miscellaneous databases

ChiTaRSi UBL5. human.
EvolutionaryTracei Q9BZL1.
GeneWikii UBL5.
GenomeRNAii 59286.
NextBioi 65186.
PROi Q9BZL1.
SOURCEi Search...

Gene expression databases

Bgeei Q9BZL1.
CleanExi HS_UBL5.
ExpressionAtlasi Q9BZL1. baseline and differential.
Genevestigatori Q9BZL1.

Family and domain databases

InterProi IPR000626. Ubiquitin-like.
IPR029071. Ubiquitin-rel_dom.
[Graphical view ]
Pfami PF00240. ubiquitin. 1 hit.
[Graphical view ]
SUPFAMi SSF54236. SSF54236. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes."
    Friedman J.S., Koop B.F., Raymond V., Walter M.A.
    Genomics 71:252-255(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Tissue: Iris.
  2. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
    Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
    Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney and Uterus.
  4. Cited for: INTERACTION WITH CLK1; CLK3 AND CLK4.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "Structural analysis of UBL5, a novel ubiquitin-like modifier."
    McNally T., Huang Q., Janis R.S., Liu Z., Olejniczak E.T., Reilly R.M.
    Protein Sci. 12:1562-1566(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: STRUCTURE BY NMR, INTERACTION WITH CLK4.

Entry informationi

Entry nameiUBL5_HUMAN
AccessioniPrimary (citable) accession number: Q9BZL1
Secondary accession number(s): Q2NL89
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 13, 2004
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3