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Protein

UPF0193 protein EVG1

Gene

C22orf23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0193 protein EVG1
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000128346.10.
HGNCiHGNC:18589. C22orf23.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000128346.
PharmGKBiPA38355.

Polymorphism and mutation databases

BioMutaiC22orf23.
DMDMi20177878.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002210891 – 217UPF0193 protein EVG1Add BLAST217

Proteomic databases

PaxDbiQ9BZE7.
PRIDEiQ9BZE7.

PTM databases

iPTMnetiQ9BZE7.
PhosphoSitePlusiQ9BZE7.

Expressioni

Gene expression databases

BgeeiENSG00000128346.
CleanExiHS_C22orf23.
ExpressionAtlasiQ9BZE7. baseline and differential.
GenevisibleiQ9BZE7. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCNDBP1O952733EBI-10303102,EBI-748961

Protein-protein interaction databases

BioGridi124168. 2 interactors.
IntActiQ9BZE7. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ9BZE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0193 (EVG1) family.Curated

Phylogenomic databases

eggNOGiENOG410IWMY. Eukaryota.
ENOG4111W8U. LUCA.
GeneTreeiENSGT00390000010231.
HOGENOMiHOG000007741.
HOVERGENiHBG023403.
InParanoidiQ9BZE7.
OMAiQGKQYRG.
OrthoDBiEOG091G0RWM.
PhylomeDBiQ9BZE7.
TreeFamiTF323579.

Family and domain databases

InterProiView protein in InterPro
IPR007914. UPF0193.
PANTHERiPTHR28348. PTHR28348. 1 hit.
PfamiView protein in Pfam
PF05250. UPF0193. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9BZE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQKQMEVV TKGTGFRRRP KTITYTPGTC ELLRVMMKES KLTNIQQRHI
60 70 80 90 100
MDIMKRGDAL PLQCSPTSSQ RVLPSKQIAS PIYLPPILAA RPHLRPANMC
110 120 130 140 150
QANGAYSREQ FKPQATRDLE KEKQRLQNIF ATGKDMEERK RKAPPARQKA
160 170 180 190 200
PAPELDRFEE LVKEIQERKE FLADMEALGQ GKQYRGIILA EISQKLREME
210
DIDHRRSEEL RKGLATT
Length:217
Mass (Da):24,956
Last modified:June 1, 2001 - v1
Checksum:i884349333B6E60F0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti33L → F in BAB71442 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_057346136M → L. Corresponds to variant dbSNP:rs35562630Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF324466 mRNA. Translation: AAK07640.1.
AK057349 mRNA. Translation: BAB71442.1.
CR456440 mRNA. Translation: CAG30326.1.
AL031587 Genomic DNA. No translation available.
CH471095 Genomic DNA. Translation: EAW60200.1.
BC031998 mRNA. Translation: AAH31998.1.
CCDSiCCDS13962.1.
RefSeqiNP_001193991.1. NM_001207062.1.
NP_115950.3. NM_032561.4.
UniGeneiHs.517612.

Genome annotation databases

EnsembliENST00000249079; ENSP00000249079; ENSG00000128346.
ENST00000403026; ENSP00000384618; ENSG00000128346.
ENST00000403305; ENSP00000384667; ENSG00000128346.
GeneIDi84645.
KEGGihsa:84645.
UCSCiuc003auj.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiEVG1_HUMAN
AccessioniPrimary (citable) accession number: Q9BZE7
Secondary accession number(s): Q5JYU9, Q96M68
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: November 22, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families
  5. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries