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Q9BZD3

- GCOM2_HUMAN

UniProt

Q9BZD3 - GCOM2_HUMAN

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Protein

Putative GRINL1B complex locus protein 2

Gene

GCOM2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Protein uncertaini

Names & Taxonomyi

Protein namesi
Recommended name:
Putative GRINL1B complex locus protein 2
Alternative name(s):
Glutamate receptor-like protein 1B
Gene namesi
Name:GCOM2
Synonyms:GRINL1B
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Unplaced

Organism-specific databases

HGNCiHGNC:15712. GCOM2.

Subcellular locationi

GO - Cellular componenti

  1. DNA-directed RNA polymerase II, holoenzyme Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 368368Putative GRINL1B complex locus protein 2PRO_0000326229Add
BLAST

Proteomic databases

MaxQBiQ9BZD3.
PRIDEiQ9BZD3.

PTM databases

PhosphoSiteiQ9BZD3.

Expressioni

Gene expression databases

GenevestigatoriQ9BZD3.

Structurei

3D structure databases

ProteinModelPortaliQ9BZD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili15 – 3925Sequence AnalysisAdd
BLAST
Coiled coili301 – 33535Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi277 – 2804Poly-Arg

Sequence similaritiesi

Belongs to the GRINL1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOVERGENiHBG098324.
InParanoidiQ9BZD3.

Family and domain databases

InterProiIPR026213. GRINL1.
[Graphical view]
PRINTSiPR02085. POLR2GRINL1.

Sequencei

Sequence statusi: Complete.

Q9BZD3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCLLPRGFEP QAPEDLAQRS LVELREMLKL QERLLRNEKF ICKLPDKGKK
60 70 80 90 100
IFDSFAKLKA AIAECEEVRR KNELFHPVSL DCKLRQKAIA EVDVGTDKAR
110 120 130 140 150
NSDPILDTSS LVPGCSSVDN IKSSQTSQNQ GLGRPTLEGD EETSEVEYTV
160 170 180 190 200
NKGPASSNRD RVPPSSEASE HHPQHRVSSQ AEDTSSSFDN LFIDRLQRIT
210 220 230 240 250
IADQGEQQSE ENASTKNLTG LSSGTQKKPH YMEVLEMRAK NPGPQLRKFK
260 270 280 290 300
TNVLPFRQND SSSHCQKSGS PISSKERRRR DKQHLDDITA ARLLPLHHMP
310 320 330 340 350
TQLLSIEESL ALQKQQKQNY EEMQAKLAAQ KLAERPNIKM RSYNPEGESS
360
GRYREVRDED DDWSSDEF
Length:368
Mass (Da):41,713
Last modified:March 18, 2008 - v2
Checksum:iA642B1D9A908BCB6
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti176 – 1761R → H in an acute myeloid leukemia sample; somatic mutation. 1 Publication
VAR_054145

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096727 Genomic DNA. No translation available.
AF326970 Genomic DNA. Translation: AAG50023.1.

Polymorphism databases

DMDMi172046229.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC096727 Genomic DNA. No translation available.
AF326970 Genomic DNA. Translation: AAG50023.1 .

3D structure databases

ProteinModelPortali Q9BZD3.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9BZD3.

Polymorphism databases

DMDMi 172046229.

Proteomic databases

MaxQBi Q9BZD3.
PRIDEi Q9BZD3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

GeneCardsi GC04P068905.
HGNCi HGNC:15712. GCOM2.
MIMi 608311. gene.
neXtProti NX_Q9BZD3.
GenAtlasi Search...

Phylogenomic databases

HOVERGENi HBG098324.
InParanoidi Q9BZD3.

Miscellaneous databases

PROi Q9BZD3.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9BZD3.

Family and domain databases

InterProi IPR026213. GRINL1.
[Graphical view ]
PRINTSi PR02085. POLR2GRINL1.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Assignment of GRINL1B, a glutamate receptor-like processed gene, to human chromosome 4q12 by in situ hybridization."
    Mohan Raj B.K., Roginski R.S., Finkernagel S.W., Sciorra L.J.
    Cytogenet. Cell Genet. 95:238-239(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 4-112, IDENTIFICATION.
  3. Cited for: VARIANT [LARGE SCALE ANALYSIS] HIS-176.

Entry informationi

Entry nameiGCOM2_HUMAN
AccessioniPrimary (citable) accession number: Q9BZD3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 29, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3