Reviewed, UniProtKB/Swiss-Prot Q9BZA8 (PC11Y_HUMAN)

Names and origin

Protein names

Recommended name:
    Protocadherin-11 Y-linked
      Short name=Protocadherin-11
Alternative name(s):
    Protocadherin-22
    Protocadherin on the Y chromosome
      Short name=PCDH-Y
    Protocadherin prostate cancer
      Short name=Protocadherin-PC

Gene names

Name:	PCDH11Y
Synonyms:	PCDH11, PCDH22, PCDHY

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1340 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Potential calcium-dependent cell-adhesion protein.
Subunit structure	Interacts with CTNNB1. Ref.2
Subcellular location	Cell membrane; Single-pass type I membrane protein Potential.
Tissue specificity	Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Expressed in apoptosis-resistant cells. Ref.2 Ref.1 Ref.4 Ref.6
Involvement in disease	A chromosomal aberration involving PCDH11Y is a cause of multiple congenital abnormalities, including severe bilateral vesicoureteral reflux (VUR) with ureterovesical junction defects. Translocation t(Y;3)(p11;p12) with ROBO2.
Sequence similarities	Contains 7 cadherin domains.

Ontologies

Keywords
Biological process	Cell adhesion
Cellular component	Cell membrane Membrane
Coding sequence diversity	Alternative splicing Chromosomal rearrangement Polymorphism
Domain	Repeat Signal Transmembrane
Ligand	Calcium
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	homophilic cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	calcium ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Note: Additional isoforms seem to exist.

Isoform 1 (identifier: Q9BZA8-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9BZA8-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1044-1048: SQRRV → TDSRT
     1049-1340: Missing.

Isoform 3 (identifier: Q9BZA8-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-21: MFRVGFLIISSSSSLSPLLLV → MTVGFNSDIS
     1044-1048: SQRRV → TDSRT
     1049-1340: Missing.

Isoform 4 (identifier: Q9BZA8-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1044-1053: SQRRVTFHLP → VGIQVSNTTF
     1054-1340: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 28	28	Potential
	Chain	29 – 1340	1312	Protocadherin-11 Y-linked		PRO_0000232764
Regions
	Topological domain	29 – 844	816	Extracellular Potential
	Transmembrane	845 – 865	21	Potential
	Topological domain	866 – 1340	475	Cytoplasmic Potential
	Domain	58 – 171	114	Cadherin 1
	Domain	172 – 281	110	Cadherin 2
	Domain	282 – 387	106	Cadherin 3
	Domain	394 – 498	105	Cadherin 4
	Domain	499 – 602	104	Cadherin 5
	Domain	603 – 705	103	Cadherin 6
	Domain	709 – 827	119	Cadherin 7
	Compositional bias	900 – 907	8	Poly-Lys
Amino acid modifications
	Glycosylation	59	1	N-linked (GlcNAc...) Potential
	Glycosylation	80	1	N-linked (GlcNAc...) Potential
	Glycosylation	86	1	N-linked (GlcNAc...) Potential
	Glycosylation	376	1	N-linked (GlcNAc...) Potential
	Glycosylation	585	1	N-linked (GlcNAc...) Potential
	Glycosylation	805	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	1 – 21	21	MFRVG…PLLLV → MTVGFNSDIS in isoform 3.		VSP_017996
	Alternative sequence	1044 – 1053	10	SQRRVTFHLP → VGIQVSNTTF in isoform 4.		VSP_017997
	Alternative sequence	1044 – 1048	5	SQRRV → TDSRT in isoform 2 and isoform 3.		VSP_017998
	Alternative sequence	1049 – 1340	292	Missing in isoform 2 and isoform 3.		VSP_017999
	Alternative sequence	1054 – 1340	287	Missing in isoform 4.		VSP_018000
	Natural variant	917	1	V → F: dbSNP rs2524543. Ref.6 Ref.3		VAR_026020
	Natural variant	1012	1	N → K: dbSNP rs2563389. Ref.6 Ref.3		VAR_026021
	Natural variant	1320	1	A → T: dbSNP rs2556900.		VAR_048576

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 10C1A56510FF4014	FASTA	1,340	146,775
	10 20 30 40 50 60 MFRVGFLIIS SSSSLSPLLL VSVVRVNTTN CHKCLLSGTY IFAVLLVCVV FHSGAQEKNY 70 80 90 100 110 120 TIREEIPENV LIGNLLKDLN LSLIPNKSLT TTMQFKLVYK TGDVPLIRIE EDTGEIFTTG 130 140 150 160 170 180 ARIDREKLCA GIPRDEHCFY EVEVAILPDE IFRLVKIRFL IEDINDNAPL FPATVINISI 190 200 210 220 230 240 PENSAINSKY TLPAAVDPDV GINGVQNYEL IKSQNIFGLD VIETPEGDKM PQLIVQKELD 250 260 270 280 290 300 REEKDTYVMK VKVEDGGFPQ RSSTAILQVS VTDTNDNHPV FKETEIEVSI PENAPVGTSV 310 320 330 340 350 360 TQLHATDADI GENAKIHFSF SNLVSNIARR LFHLNATTGL ITIKEPLDRE ETPNHKLLVL 370 380 390 400 410 420 ASDGGLMPAR AMVLVNVTDV NDNVPSIDIR YIVNPVNDTV VLSENIPLNT KIALITVTDK 430 440 450 460 470 480 DADHNGRVTC FTDHEIPFRL RPVFSNQFLL ENAAYLDYES TKEYAIKLLA ADAGKPPLNQ 490 500 510 520 530 540 SAMLFIKVKD ENDNAPVFTQ SFVTVSIPEN NSPGIQLMKV SATDADSGPN AEINYLLGPD 550 560 570 580 590 600 APPEFSLDRR TGMLTVVKKL DREKEDKYLF TILAKDNGVP PLTSNVTVFV SIIDQNDNSP 610 620 630 640 650 660 VFTHNEYKFY VPENLPRHGT VGLITVTDPD YGDNSAVTLS ILDENDDFTI DSQTGVIRPN 670 680 690 700 710 720 ISFDREKQES YTFYVKAEDG GRVSRSSSAK VTINVVDVND NKPVFIVPPY NYSYELVLPS 730 740 750 760 770 780 TNPGTVVFQV IAVDNDTGMN AEVRYSIVGG NTRDLFAIDQ ETGNITLMEK CDVTDLGLHR 790 800 810 820 830 840 VLVKANDLGQ PDSLFSVVIV NLFVNESVTN ATLINELVRK SIEAPVTPNT EIADVSSPTS 850 860 870 880 890 900 DYVKILVAAV AGTITVVVVI FITAVVRCRQ APHLKAAQKN MQNSEWATPN PENRQMIMMK 910 920 930 940 950 960 KKKKKKKHSP KNLLLNVVTI EETKADDVDS DGNRVTLDLP IDLEEQTMGK YNWVTTPTTF 970 980 990 1000 1010 1020 KPDSPDLARH YKSASPQPAF QIQPETPLNL KHHIIQELPL DNTFVACDSI SNCSSSSSDP 1030 1040 1050 1060 1070 1080 YSVSDCGYPV TTFEVPVSVH TRPSQRRVTF HLPEGSQESS SDGGLGDHDA GSLTSTSHGL 1090 1100 1110 1120 1130 1140 PLGYPQEEYF DRATPSNRTE GDGNSDPEST FIPGLKKEIT VQPTVEEASD NCTQECLIYG 1150 1160 1170 1180 1190 1200 HSDACWMPAS LDHSSSSQAQ ASALCHSPPL SQASTQHHSP PVTQTIVLCH SPPVTQTIAL 1210 1220 1230 1240 1250 1260 CHSPPPIQVS ALHHSPPLVQ GTALHHSPPS AQASALCYSP PLAQAAAISH SSSLPQVIAL 1270 1280 1290 1300 1310 1320 HRSQAQSSVS LQQGWVQGAN GLCSVDQGVQ GSATSQFYTM SERLHPSDDS IKVIPLTTFA 1330 1340 PRQQARPSRG DSPIMETHPL
	Isoform 2. Checksum: AC0796ACEBD304E9	FASTA	1,048	115,920
	10 20 30 40 50 60 MFRVGFLIIS SSSSLSPLLL VSVVRVNTTN CHKCLLSGTY IFAVLLVCVV FHSGAQEKNY 70 80 90 100 110 120 TIREEIPENV LIGNLLKDLN LSLIPNKSLT TTMQFKLVYK TGDVPLIRIE EDTGEIFTTG 130 140 150 160 170 180 ARIDREKLCA GIPRDEHCFY EVEVAILPDE IFRLVKIRFL IEDINDNAPL FPATVINISI 190 200 210 220 230 240 PENSAINSKY TLPAAVDPDV GINGVQNYEL IKSQNIFGLD VIETPEGDKM PQLIVQKELD 250 260 270 280 290 300 REEKDTYVMK VKVEDGGFPQ RSSTAILQVS VTDTNDNHPV FKETEIEVSI PENAPVGTSV 310 320 330 340 350 360 TQLHATDADI GENAKIHFSF SNLVSNIARR LFHLNATTGL ITIKEPLDRE ETPNHKLLVL 370 380 390 400 410 420 ASDGGLMPAR AMVLVNVTDV NDNVPSIDIR YIVNPVNDTV VLSENIPLNT KIALITVTDK 430 440 450 460 470 480 DADHNGRVTC FTDHEIPFRL RPVFSNQFLL ENAAYLDYES TKEYAIKLLA ADAGKPPLNQ 490 500 510 520 530 540 SAMLFIKVKD ENDNAPVFTQ SFVTVSIPEN NSPGIQLMKV SATDADSGPN AEINYLLGPD 550 560 570 580 590 600 APPEFSLDRR TGMLTVVKKL DREKEDKYLF TILAKDNGVP PLTSNVTVFV SIIDQNDNSP 610 620 630 640 650 660 VFTHNEYKFY VPENLPRHGT VGLITVTDPD YGDNSAVTLS ILDENDDFTI DSQTGVIRPN 670 680 690 700 710 720 ISFDREKQES YTFYVKAEDG GRVSRSSSAK VTINVVDVND NKPVFIVPPY NYSYELVLPS 730 740 750 760 770 780 TNPGTVVFQV IAVDNDTGMN AEVRYSIVGG NTRDLFAIDQ ETGNITLMEK CDVTDLGLHR 790 800 810 820 830 840 VLVKANDLGQ PDSLFSVVIV NLFVNESVTN ATLINELVRK SIEAPVTPNT EIADVSSPTS 850 860 870 880 890 900 DYVKILVAAV AGTITVVVVI FITAVVRCRQ APHLKAAQKN MQNSEWATPN PENRQMIMMK 910 920 930 940 950 960 KKKKKKKHSP KNLLLNVVTI EETKADDVDS DGNRVTLDLP IDLEEQTMGK YNWVTTPTTF 970 980 990 1000 1010 1020 KPDSPDLARH YKSASPQPAF QIQPETPLNL KHHIIQELPL DNTFVACDSI SNCSSSSSDP 1030 1040 YSVSDCGYPV TTFEVPVSVH TRPTDSRT
	Isoform 3. Checksum: 72CB8AB1EBA9ACCC	FASTA	1,037	114,723
	10 20 30 40 50 60 MTVGFNSDIS SVVRVNTTNC HKCLLSGTYI FAVLLVCVVF HSGAQEKNYT IREEIPENVL 70 80 90 100 110 120 IGNLLKDLNL SLIPNKSLTT TMQFKLVYKT GDVPLIRIEE DTGEIFTTGA RIDREKLCAG 130 140 150 160 170 180 IPRDEHCFYE VEVAILPDEI FRLVKIRFLI EDINDNAPLF PATVINISIP ENSAINSKYT 190 200 210 220 230 240 LPAAVDPDVG INGVQNYELI KSQNIFGLDV IETPEGDKMP QLIVQKELDR EEKDTYVMKV 250 260 270 280 290 300 KVEDGGFPQR SSTAILQVSV TDTNDNHPVF KETEIEVSIP ENAPVGTSVT QLHATDADIG 310 320 330 340 350 360 ENAKIHFSFS NLVSNIARRL FHLNATTGLI TIKEPLDREE TPNHKLLVLA SDGGLMPARA 370 380 390 400 410 420 MVLVNVTDVN DNVPSIDIRY IVNPVNDTVV LSENIPLNTK IALITVTDKD ADHNGRVTCF 430 440 450 460 470 480 TDHEIPFRLR PVFSNQFLLE NAAYLDYEST KEYAIKLLAA DAGKPPLNQS AMLFIKVKDE 490 500 510 520 530 540 NDNAPVFTQS FVTVSIPENN SPGIQLMKVS ATDADSGPNA EINYLLGPDA PPEFSLDRRT 550 560 570 580 590 600 GMLTVVKKLD REKEDKYLFT ILAKDNGVPP LTSNVTVFVS IIDQNDNSPV FTHNEYKFYV 610 620 630 640 650 660 PENLPRHGTV GLITVTDPDY GDNSAVTLSI LDENDDFTID SQTGVIRPNI SFDREKQESY 670 680 690 700 710 720 TFYVKAEDGG RVSRSSSAKV TINVVDVNDN KPVFIVPPYN YSYELVLPST NPGTVVFQVI 730 740 750 760 770 780 AVDNDTGMNA EVRYSIVGGN TRDLFAIDQE TGNITLMEKC DVTDLGLHRV LVKANDLGQP 790 800 810 820 830 840 DSLFSVVIVN LFVNESVTNA TLINELVRKS IEAPVTPNTE IADVSSPTSD YVKILVAAVA 850 860 870 880 890 900 GTITVVVVIF ITAVVRCRQA PHLKAAQKNM QNSEWATPNP ENRQMIMMKK KKKKKKHSPK 910 920 930 940 950 960 NLLLNVVTIE ETKADDVDSD GNRVTLDLPI DLEEQTMGKY NWVTTPTTFK PDSPDLARHY 970 980 990 1000 1010 1020 KSASPQPAFQ IQPETPLNLK HHIIQELPLD NTFVACDSIS NCSSSSSDPY SVSDCGYPVT 1030 TFEVPVSVHT RPTDSRT
	Isoform 4. Checksum: 0DD1C6721B4F6553	FASTA	1,053	116,406
	10 20 30 40 50 60 MFRVGFLIIS SSSSLSPLLL VSVVRVNTTN CHKCLLSGTY IFAVLLVCVV FHSGAQEKNY 70 80 90 100 110 120 TIREEIPENV LIGNLLKDLN LSLIPNKSLT TTMQFKLVYK TGDVPLIRIE EDTGEIFTTG 130 140 150 160 170 180 ARIDREKLCA GIPRDEHCFY EVEVAILPDE IFRLVKIRFL IEDINDNAPL FPATVINISI 190 200 210 220 230 240 PENSAINSKY TLPAAVDPDV GINGVQNYEL IKSQNIFGLD VIETPEGDKM PQLIVQKELD 250 260 270 280 290 300 REEKDTYVMK VKVEDGGFPQ RSSTAILQVS VTDTNDNHPV FKETEIEVSI PENAPVGTSV 310 320 330 340 350 360 TQLHATDADI GENAKIHFSF SNLVSNIARR LFHLNATTGL ITIKEPLDRE ETPNHKLLVL 370 380 390 400 410 420 ASDGGLMPAR AMVLVNVTDV NDNVPSIDIR YIVNPVNDTV VLSENIPLNT KIALITVTDK 430 440 450 460 470 480 DADHNGRVTC FTDHEIPFRL RPVFSNQFLL ENAAYLDYES TKEYAIKLLA ADAGKPPLNQ 490 500 510 520 530 540 SAMLFIKVKD ENDNAPVFTQ SFVTVSIPEN NSPGIQLMKV SATDADSGPN AEINYLLGPD 550 560 570 580 590 600 APPEFSLDRR TGMLTVVKKL DREKEDKYLF TILAKDNGVP PLTSNVTVFV SIIDQNDNSP 610 620 630 640 650 660 VFTHNEYKFY VPENLPRHGT VGLITVTDPD YGDNSAVTLS ILDENDDFTI DSQTGVIRPN 670 680 690 700 710 720 ISFDREKQES YTFYVKAEDG GRVSRSSSAK VTINVVDVND NKPVFIVPPY NYSYELVLPS 730 740 750 760 770 780 TNPGTVVFQV IAVDNDTGMN AEVRYSIVGG NTRDLFAIDQ ETGNITLMEK CDVTDLGLHR 790 800 810 820 830 840 VLVKANDLGQ PDSLFSVVIV NLFVNESVTN ATLINELVRK SIEAPVTPNT EIADVSSPTS 850 860 870 880 890 900 DYVKILVAAV AGTITVVVVI FITAVVRCRQ APHLKAAQKN MQNSEWATPN PENRQMIMMK 910 920 930 940 950 960 KKKKKKKHSP KNLLLNVVTI EETKADDVDS DGNRVTLDLP IDLEEQTMGK YNWVTTPTTF 970 980 990 1000 1010 1020 KPDSPDLARH YKSASPQPAF QIQPETPLNL KHHIIQELPL DNTFVACDSI SNCSSSSSDP 1030 1040 1050 YSVSDCGYPV TTFEVPVSVH TRPVGIQVSN TTF

References

[1]	"Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain." Blanco P., Sargent C.A., Boucher C., Mitchell M., Affara N. Mamm. Genome 11:906-914(2000) [PubMed: 11003707] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), TISSUE SPECIFICITY. Tissue: Brain.
[2]	"The emergence of protocadherin-PC expression during the acquisition of apoptosis-resistance by prostate cancer cells." Chen M.-W., Vacherot F., De La Taille A., Gil-Diez-De-Medina S., Shen R., Friedman R.A., Burchardt M., Chopin D.K., Buttyan R. Oncogene 21:7861-7871(2002) [PubMed: 12420223] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), INTERACTION WITH CTNNB1, SUBCELLULAR LOCATION, TISSUE SPECIFICITY. Tissue: Prostatic carcinoma.
[3]	"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C. Nature 423:825-837(2003) [PubMed: 12815422] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), VARIANTS PHE-917 AND LYS-1012. Tissue: Brain.
[4]	"Protocadherin X (PCDHX) and Y (PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains." Blanco-Arias P., Sargent C.A., Affara N.A. Mamm. Genome 15:41-52(2004) [PubMed: 14727141] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1109 AND 1119-1340, NUCLEOTIDE SEQUENCE [MRNA] OF 213-1340 (ISOFORM 4), TISSUE SPECIFICITY, ALTERNATIVE SPLICING.
[5]	"Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux." Lu W., van Eerde A.M., Fan X., Quintero-Rivera F., Kulkarni S., Ferguson H., Kim H.-G., Fan Y., Xi Q., Li Q.-G., Sanlaville D., Andrews W., Sundaresan V., Bi W., Yan J., Giltay J.C., Wijmenga C., de Jong T.P.V.M. , Feather S.A., Woolf A.S., Rao Y., Lupski J.R., Eccles M.R., Quade B.J., Gusella J.F., Morton C.C., Maas R.L. Am. J. Hum. Genet. 80:616-632(2007) [PubMed: 17357069] [Abstract] Cited for: CHROMOSOMAL TRANSLOCATION WITH ROBO2.
[6]	"Expression and genetic variability of PCDH11Y, a gene specific to Homo sapiens and candidate for susceptibility to psychiatric disorders." Durand C.M., Kappeler C., Betancur C., Delorme R., Quach H., Goubran-Botros H., Melke J., Nygren G., Chabane N., Bellivier F., Szoke A., Schurhoff F., Rastam M., Anckarsaeter H., Gillberg C., Leboyer M., Bourgeron T. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141:67-70(2006) [PubMed: 16331680] [Abstract] Cited for: VARIANTS PHE-917 AND LYS-1012, TISSUE SPECIFICITY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ276803 mRNA. Translation: CAC13122.1. AF277053 mRNA. Translation: AAL55729.1. AF332216 mRNA. Translation: AAK13468.1. AF332217 mRNA. Translation: AAK13469.1. AJ564958 mRNA. Translation: CAD92429.1. AJ564959 mRNA. Translation: CAD92430.1. AJ564960 mRNA. Translation: CAD92431.1. AJ564961 mRNA. Translation: CAD92432.1. AJ564962 mRNA. Translation: CAD92433.1. AJ564963 mRNA. Translation: CAD92434.1. AJ564966 mRNA. Translation: CAD92437.1. AJ564969 mRNA. Translation: CAD92440.1.
IPI	IPI00018320. IPI00104649. IPI00218387. IPI00745536.
RefSeq	NP_116753.1. NP_116754.1. NP_116755.1.
UniGene	Hs.655673 Hs.661308
3D structure databases
HSSP	HSSP built from PDB template 1FF5 based on UniProtKB P09803.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9BZA8.
Proteomic databases
PRIDE	Q9BZA8.
Genome annotation databases
Ensembl	ENST00000215473; ENSP00000215473; ENSG00000099715; Homo sapiens. [Genome view] ENST00000333703; ENSP00000330552; ENSG00000099715; Homo sapiens. [Genome view] ENST00000362095; ENSP00000355419; ENSG00000099715; Homo sapiens. [Genome view] ENST00000400457; ENSP00000383306; ENSG00000099715; Homo sapiens. [Genome view]
GeneID	83259.
KEGG	hsa:83259.
UCSC	uc004fql.1. human. uc004fqn.1. human. uc004fqo.1. human.
Organism-specific databases
CTD	83259.
GeneCards	GC0YP004911.
H-InvDB	HIX0017181.
HGNC	HGNC:15813. PCDH11Y.
HPA	HPA000432.
MIM	400022. gene.
PharmGKB	PA32997.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q9BZA8.
Gene expression databases
Genevestigator	Q9BZA8.
GermOnline	ENSG00000099715. Homo sapiens.
Family and domain databases
InterPro	IPR002126. Cadherin. IPR013164. Cadherin_N. IPR013585. Protocadherin. [Graphical view]
Gene3D	G3DSA:2.60.40.60. Cadherin. 6 hits.
Pfam	PF00028. Cadherin. 6 hits. PF08266. Cadherin_2. 1 hit. PF08374. Protocadherin. 1 hit. [Graphical view]
PRINTS	PR00205. CADHERIN.
SMART	SM00112. CA. 6 hits. [Graphical view]
PROSITE	PS00232. CADHERIN_1. 5 hits. PS50268. CADHERIN_2. 7 hits. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	72287.
SOURCE	Search...

Entry information

Entry name

PC11Y_HUMAN

Accession

Primary (citable) accession number: Q9BZA8
Secondary accession number(s): Q70LR6 , Q70LR8, Q70LS0, Q70LS1, Q70LS2, Q70LS3, Q70LS4, Q70LS5, Q8WY34, Q9BZA9, Q9H4E1

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
Last sequence update:	June 1, 2001
Last modified:	October 13, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.