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Protein

Protocadherin-11 X-linked

Gene

PCDH11X

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

Potential calcium-dependent cell-adhesion protein.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesion

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Protocadherin-11 X-linked
Short name:
Protocadherin-11
Alternative name(s):
Protocadherin on the X chromosome
Short name:
PCDH-X
Protocadherin-S
Gene namesi
Name:PCDH11X
Synonyms:KIAA1326, PCDH11, PCDHX
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:8656. PCDH11X.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini24 – 812ExtracellularSequence analysisAdd BLAST789
Transmembranei813 – 833HelicalSequence analysisAdd BLAST21
Topological domaini834 – 1347CytoplasmicSequence analysisAdd BLAST514

GO - Cellular componenti

  • extracellular exosome Source: UniProtKB
  • integral component of plasma membrane Source: ProtInc
  • plasma membrane Source: ProtInc
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi27328.
OpenTargetsiENSG00000102290.
PharmGKBiPA32996.

Polymorphism and mutation databases

BioMutaiPCDH11X.
DMDMi74761344.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000023275824 – 1347Protocadherin-11 X-linkedAdd BLAST1324

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi27N-linked (GlcNAc...)Sequence analysis1
Glycosylationi48N-linked (GlcNAc...)Sequence analysis1
Glycosylationi54N-linked (GlcNAc...)Sequence analysis1
Glycosylationi344N-linked (GlcNAc...)Sequence analysis1
Glycosylationi553N-linked (GlcNAc...)Sequence analysis1
Glycosylationi773N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9BZA7.
PeptideAtlasiQ9BZA7.
PRIDEiQ9BZA7.

PTM databases

iPTMnetiQ9BZA7.
PhosphoSitePlusiQ9BZA7.

Expressioni

Tissue specificityi

Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis.2 Publications

Gene expression databases

BgeeiENSG00000102290.
ExpressionAtlasiQ9BZA7. baseline and differential.
GenevisibleiQ9BZA7. HS.

Organism-specific databases

HPAiHPA000432.

Interactioni

Protein-protein interaction databases

BioGridi118142. 1 interactor.
IntActiQ9BZA7. 1 interactor.
STRINGi9606.ENSP00000362186.

Structurei

3D structure databases

ProteinModelPortaliQ9BZA7.
SMRiQ9BZA7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 139Cadherin 1PROSITE-ProRule annotationAdd BLAST114
Domaini140 – 249Cadherin 2PROSITE-ProRule annotationAdd BLAST110
Domaini250 – 355Cadherin 3PROSITE-ProRule annotationAdd BLAST106
Domaini362 – 466Cadherin 4PROSITE-ProRule annotationAdd BLAST105
Domaini467 – 570Cadherin 5PROSITE-ProRule annotationAdd BLAST104
Domaini571 – 673Cadherin 6PROSITE-ProRule annotationAdd BLAST103
Domaini677 – 795Cadherin 7PROSITE-ProRule annotationAdd BLAST119

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi868 – 875Poly-Lys8

Sequence similaritiesi

Contains 7 cadherin domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00850000132246.
HOVERGENiHBG053523.
InParanoidiQ9BZA7.
KOiK16498.
OMAiPEGEKMP.
OrthoDBiEOG091G011P.
PhylomeDBiQ9BZA7.
TreeFamiTF320624.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR013585. Protocadherin.
[Graphical view]
PfamiPF00028. Cadherin. 6 hits.
PF08266. Cadherin_2. 1 hit.
PF08374. Protocadherin. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 6 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 7 hits.
[Graphical view]

Sequences (8)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 8 isoformsi produced by alternative splicing. AlignAdd to basket

Note: Additional isoforms seem to exist.
Isoform 1 (identifier: Q9BZA7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MDLLSGTYIF AVLLACVVFH SGAQEKNYTI REEMPENVLI GDLLKDLNLS
60 70 80 90 100
LIPNKSLTTA MQFKLVYKTG DVPLIRIEED TGEIFTTGAR IDREKLCAGI
110 120 130 140 150
PRDEHCFYEV EVAILPDEIF RLVKIRFLIE DINDNAPLFP ATVINISIPE
160 170 180 190 200
NSAINSKYTL PAAVDPDVGI NGVQNYELIK SQNIFGLDVI ETPEGDKMPQ
210 220 230 240 250
LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVT DTNDNHPVFK
260 270 280 290 300
ETEIEVSIPE NAPVGTSVTQ LHATDADIGE NAKIHFSFSN LVSNIARRLF
310 320 330 340 350
HLNATTGLIT IKEPLDREET PNHKLLVLAS DGGLMPARAM VLVNVTDVND
360 370 380 390 400
NVPSIDIRYI VNPVNDTVVL SENIPLNTKI ALITVTDKDA DHNGRVTCFT
410 420 430 440 450
DHEIPFRLRP VFSNQFLLET AAYLDYESTK EYAIKLLAAD AGKPPLNQSA
460 470 480 490 500
MLFIKVKDEN DNAPVFTQSF VTVSIPENNS PGIQLTKVSA MDADSGPNAK
510 520 530 540 550
INYLLGPDAP PEFSLDCRTG MLTVVKKLDR EKEDKYLFTI LAKDNGVPPL
560 570 580 590 600
TSNVTVFVSI IDQNDNSPVF THNEYNFYVP ENLPRHGTVG LITVTDPDYG
610 620 630 640 650
DNSAVTLSIL DENDDFTIDS QTGVIRPNIS FDREKQESYT FYVKAEDGGR
660 670 680 690 700
VSRSSSAKVT INVVDVNDNK PVFIVPPSNC SYELVLPSTN PGTVVFQVIA
710 720 730 740 750
VDNDTGMNAE VRYSIVGGNT RDLFAIDQET GNITLMEKCD VTDLGLHRVL
760 770 780 790 800
VKANDLGQPD SLFSVVIVNL FVNESVTNAT LINELVRKST EAPVTPNTEI
810 820 830 840 850
ADVSSPTSDY VKILVAAVAG TITVVVVIFI TAVVRCRQAP HLKAAQKNKQ
860 870 880 890 900
NSEWATPNPE NRQMIMMKKK KKKKKHSPKN LLLNFVTIEE TKADDVDSDG
910 920 930 940 950
NRVTLDLPID LEEQTMGKYN WVTTPTTFKP DSPDLARHYK SASPQPAFQI
960 970 980 990 1000
QPETPLNSKH HIIQELPLDN TFVACDSISK CSSSSSDPYS VSDCGYPVTT
1010 1020 1030 1040 1050
FEVPVSVHTR PPMKEVVRSC TPMKESTTME IWIHPQPQRK SEGKVAGKSQ
1060 1070 1080 1090 1100
RRVTFHLPEG SQESSSDGGL GDHDAGSLTS TSHGLPLGYP QEEYFDRATP
1110 1120 1130 1140 1150
SNRTEGDGNS DPESTFIPGL KKAAEITVQP TVEEASDNCT QECLIYGHSD
1160 1170 1180 1190 1200
ACWMPASLDH SSSSQAQASA LCHSPPLSQA STQHHSPRVT QTIALCHSPP
1210 1220 1230 1240 1250
VTQTIALCHS PPPIQVSALH HSPPLVQATA LHHSPPSAQA SALCYSPPLA
1260 1270 1280 1290 1300
QAAAISHSSP LPQVIALHRS QAQSSVSLQQ GWVQGADGLC SVDQGVQGSA
1310 1320 1330 1340
TSQFYTMSER LHPSDDSIKV IPLTTFTPRQ QARPSRGDSP IMEEHPL
Length:1,347
Mass (Da):147,558
Last modified:June 1, 2001 - v1
Checksum:i0227FA6C521FDA84
GO
Isoform 2 (identifier: Q9BZA7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1012-1025: PMKEVVRSCTPMKE → TDSRTSTIEICSEI
     1026-1347: Missing.

Show »
Length:1,025
Mass (Da):113,215
Checksum:i51EE095ED7035A10
GO
Isoform 3 (identifier: Q9BZA7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1039-1048: Missing.

Show »
Length:1,337
Mass (Da):146,517
Checksum:iA96D3B41173C8508
GO
Isoform 4 (identifier: Q9BZA7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1039-1048: Missing.
     1116-1123: Missing.

Show »
Length:1,329
Mass (Da):145,662
Checksum:iDA7DC585324AD261
GO
Isoform 5 (identifier: Q9BZA7-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1012-1048: Missing.

Show »
Length:1,310
Mass (Da):143,350
Checksum:i948FE29C9EA7D312
GO
Isoform 6 (identifier: Q9BZA7-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1049-1065: SQRRVTFHLPEGSQESS → TVLTSSSPSAMTLSYLD
     1066-1347: Missing.

Show »
Length:1,065
Mass (Da):117,642
Checksum:i71AB11952A3EEA81
GO
Isoform 7 (identifier: Q9BZA7-7) [UniParc]FASTAAdd to basket
Also known as: Protocadherin-Xa

The sequence of this isoform differs from the canonical sequence as follows:
     1012-1021: PMKEVVRSCT → VGIQVSNTTF
     1022-1347: Missing.

Note: No experimental confirmation available.
Show »
Length:1,021
Mass (Da):112,726
Checksum:i9F4471F5C597F902
GO
Isoform 8 (identifier: Q9BZA7-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1116-1123: Missing.

Show »
Length:1,339
Mass (Da):146,703
Checksum:iCD1D563B7D8FE105
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti242 – 244TND → PNA in AAK82655 (Ref. 4) Curated3
Sequence conflicti242 – 244TND → PNA in AAK82656 (Ref. 4) Curated3
Sequence conflicti252T → P in AAK82655 (Ref. 4) Curated1
Sequence conflicti252T → P in AAK82656 (Ref. 4) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03610942D → G in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_0485751018R → Q.Corresponds to variant rs4252205dbSNPEnsembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0179791012 – 1048Missing in isoform 5. 2 PublicationsAdd BLAST37
Alternative sequenceiVSP_0179801012 – 1025PMKEV…TPMKE → TDSRTSTIEICSEI in isoform 2. 1 PublicationAdd BLAST14
Alternative sequenceiVSP_0179811012 – 1021PMKEVVRSCT → VGIQVSNTTF in isoform 7. 2 Publications10
Alternative sequenceiVSP_0179821022 – 1347Missing in isoform 7. 2 PublicationsAdd BLAST326
Alternative sequenceiVSP_0179831026 – 1347Missing in isoform 2. 1 PublicationAdd BLAST322
Alternative sequenceiVSP_0179841039 – 1048Missing in isoform 3 and isoform 4. 2 Publications10
Alternative sequenceiVSP_0179851049 – 1065SQRRV…SQESS → TVLTSSSPSAMTLSYLD in isoform 6. 1 PublicationAdd BLAST17
Alternative sequenceiVSP_0179861066 – 1347Missing in isoform 6. 1 PublicationAdd BLAST282
Alternative sequenceiVSP_0179871116 – 1123Missing in isoform 8 and isoform 4. 1 Publication8

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026187 mRNA. Translation: BAA90765.1.
AJ276804 mRNA. Translation: CAC13123.1.
AF332218 mRNA. Translation: AAK13470.1.
AF332219 mRNA. Translation: AAK13471.1.
AF206516 mRNA. Translation: AAK82655.1.
AF217288 mRNA. Translation: AAK82656.1.
AY861432 mRNA. Translation: AAX56122.1.
AY861433 mRNA. Translation: AAX56123.1.
AY861434 mRNA. Translation: AAX56124.1.
AY861435 mRNA. Translation: AAX56125.1.
AL121869, AC004388, AL133274 Genomic DNA. Translation: CAI41412.1.
AL121869
, AC004388, AL133274, AL133321 Genomic DNA. Translation: CAI41413.1.
AL121869
, AC004388, AL133274, AL133321 Genomic DNA. Translation: CAI41414.1.
AL133321
, AC004388, AL121869, AL133274 Genomic DNA. Translation: CAI41435.1.
AL133321
, AC004388, AL121869, AL133274 Genomic DNA. Translation: CAI41436.1.
AL133274, AC004388, AL121869 Genomic DNA. Translation: CAI41629.1.
AL133274
, AC004388, AL121869, AL133321 Genomic DNA. Translation: CAI41630.1.
AL133274
, AC004388, AL121869, AL133321 Genomic DNA. Translation: CAI41631.1.
AJ564931 mRNA. Translation: CAD92410.1.
AJ564932 mRNA. Translation: CAD92411.1.
AJ564933 mRNA. Translation: CAD92412.1.
AJ564934 mRNA. Translation: CAD92413.1.
AJ564935 mRNA. Translation: CAD92414.1.
AJ564936 mRNA. Translation: CAD92415.1.
AJ564942 mRNA. Translation: CAD92421.1.
AJ564945 mRNA. Translation: CAD92424.1.
AJ564946 mRNA. Translation: CAD92425.1.
AJ564947 mRNA. Translation: CAD92426.1.
AB037747 mRNA. Translation: BAA92564.1.
CCDSiCCDS14461.1. [Q9BZA7-1]
CCDS14462.1. [Q9BZA7-3]
CCDS55458.1. [Q9BZA7-6]
CCDS55459.1. [Q9BZA7-8]
CCDS55460.1. [Q9BZA7-4]
CCDS55461.1. [Q9BZA7-5]
RefSeqiNP_001161832.1. NM_001168360.1. [Q9BZA7-8]
NP_001161833.1. NM_001168361.1. [Q9BZA7-6]
NP_001161834.1. NM_001168362.1. [Q9BZA7-5]
NP_001161835.1. NM_001168363.1. [Q9BZA7-4]
NP_116750.1. NM_032968.4. [Q9BZA7-1]
NP_116751.1. NM_032969.4. [Q9BZA7-3]
XP_011529216.1. XM_011530914.2. [Q9BZA7-1]
XP_016884911.1. XM_017029422.1. [Q9BZA7-2]
UniGeneiHs.655673.

Genome annotation databases

EnsembliENST00000361655; ENSP00000355105; ENSG00000102290. [Q9BZA7-4]
ENST00000373088; ENSP00000362180; ENSG00000102290. [Q9BZA7-5]
ENST00000373094; ENSP00000362186; ENSG00000102290. [Q9BZA7-1]
ENST00000373097; ENSP00000362189; ENSG00000102290. [Q9BZA7-3]
ENST00000406881; ENSP00000384758; ENSG00000102290. [Q9BZA7-8]
ENST00000504220; ENSP00000423762; ENSG00000102290. [Q9BZA7-6]
GeneIDi27328.
KEGGihsa:27328.
UCSCiuc004efk.3. human. [Q9BZA7-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026187 mRNA. Translation: BAA90765.1.
AJ276804 mRNA. Translation: CAC13123.1.
AF332218 mRNA. Translation: AAK13470.1.
AF332219 mRNA. Translation: AAK13471.1.
AF206516 mRNA. Translation: AAK82655.1.
AF217288 mRNA. Translation: AAK82656.1.
AY861432 mRNA. Translation: AAX56122.1.
AY861433 mRNA. Translation: AAX56123.1.
AY861434 mRNA. Translation: AAX56124.1.
AY861435 mRNA. Translation: AAX56125.1.
AL121869, AC004388, AL133274 Genomic DNA. Translation: CAI41412.1.
AL121869
, AC004388, AL133274, AL133321 Genomic DNA. Translation: CAI41413.1.
AL121869
, AC004388, AL133274, AL133321 Genomic DNA. Translation: CAI41414.1.
AL133321
, AC004388, AL121869, AL133274 Genomic DNA. Translation: CAI41435.1.
AL133321
, AC004388, AL121869, AL133274 Genomic DNA. Translation: CAI41436.1.
AL133274, AC004388, AL121869 Genomic DNA. Translation: CAI41629.1.
AL133274
, AC004388, AL121869, AL133321 Genomic DNA. Translation: CAI41630.1.
AL133274
, AC004388, AL121869, AL133321 Genomic DNA. Translation: CAI41631.1.
AJ564931 mRNA. Translation: CAD92410.1.
AJ564932 mRNA. Translation: CAD92411.1.
AJ564933 mRNA. Translation: CAD92412.1.
AJ564934 mRNA. Translation: CAD92413.1.
AJ564935 mRNA. Translation: CAD92414.1.
AJ564936 mRNA. Translation: CAD92415.1.
AJ564942 mRNA. Translation: CAD92421.1.
AJ564945 mRNA. Translation: CAD92424.1.
AJ564946 mRNA. Translation: CAD92425.1.
AJ564947 mRNA. Translation: CAD92426.1.
AB037747 mRNA. Translation: BAA92564.1.
CCDSiCCDS14461.1. [Q9BZA7-1]
CCDS14462.1. [Q9BZA7-3]
CCDS55458.1. [Q9BZA7-6]
CCDS55459.1. [Q9BZA7-8]
CCDS55460.1. [Q9BZA7-4]
CCDS55461.1. [Q9BZA7-5]
RefSeqiNP_001161832.1. NM_001168360.1. [Q9BZA7-8]
NP_001161833.1. NM_001168361.1. [Q9BZA7-6]
NP_001161834.1. NM_001168362.1. [Q9BZA7-5]
NP_001161835.1. NM_001168363.1. [Q9BZA7-4]
NP_116750.1. NM_032968.4. [Q9BZA7-1]
NP_116751.1. NM_032969.4. [Q9BZA7-3]
XP_011529216.1. XM_011530914.2. [Q9BZA7-1]
XP_016884911.1. XM_017029422.1. [Q9BZA7-2]
UniGeneiHs.655673.

3D structure databases

ProteinModelPortaliQ9BZA7.
SMRiQ9BZA7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi118142. 1 interactor.
IntActiQ9BZA7. 1 interactor.
STRINGi9606.ENSP00000362186.

PTM databases

iPTMnetiQ9BZA7.
PhosphoSitePlusiQ9BZA7.

Polymorphism and mutation databases

BioMutaiPCDH11X.
DMDMi74761344.

Proteomic databases

PaxDbiQ9BZA7.
PeptideAtlasiQ9BZA7.
PRIDEiQ9BZA7.

Protocols and materials databases

DNASUi27328.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000361655; ENSP00000355105; ENSG00000102290. [Q9BZA7-4]
ENST00000373088; ENSP00000362180; ENSG00000102290. [Q9BZA7-5]
ENST00000373094; ENSP00000362186; ENSG00000102290. [Q9BZA7-1]
ENST00000373097; ENSP00000362189; ENSG00000102290. [Q9BZA7-3]
ENST00000406881; ENSP00000384758; ENSG00000102290. [Q9BZA7-8]
ENST00000504220; ENSP00000423762; ENSG00000102290. [Q9BZA7-6]
GeneIDi27328.
KEGGihsa:27328.
UCSCiuc004efk.3. human. [Q9BZA7-1]

Organism-specific databases

CTDi27328.
DisGeNETi27328.
GeneCardsiPCDH11X.
H-InvDBHIX0176577.
HGNCiHGNC:8656. PCDH11X.
HPAiHPA000432.
MIMi300246. gene.
neXtProtiNX_Q9BZA7.
OpenTargetsiENSG00000102290.
PharmGKBiPA32996.
HUGEiSearch...
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00850000132246.
HOVERGENiHBG053523.
InParanoidiQ9BZA7.
KOiK16498.
OMAiPEGEKMP.
OrthoDBiEOG091G011P.
PhylomeDBiQ9BZA7.
TreeFamiTF320624.

Miscellaneous databases

ChiTaRSiPCDH11X. human.
GeneWikiiPCDH11X.
GenomeRNAii27328.
PROiQ9BZA7.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000102290.
ExpressionAtlasiQ9BZA7. baseline and differential.
GenevisibleiQ9BZA7. HS.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR013585. Protocadherin.
[Graphical view]
PfamiPF00028. Cadherin. 6 hits.
PF08266. Cadherin_2. 1 hit.
PF08374. Protocadherin. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 6 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 7 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPC11X_HUMAN
AccessioniPrimary (citable) accession number: Q9BZA7
Secondary accession number(s): A6NIQ4
, Q2TJH0, Q2TJH1, Q2TJH3, Q5JVZ0, Q70LR8, Q70LS7, Q70LS8, Q70LS9, Q70LT7, Q70LT8, Q70LT9, Q70LU0, Q70LU1, Q96RV4, Q96RW0, Q9BZA6, Q9H4E0, Q9P2M0, Q9P2X5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 129 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.