ID   FR8P1_HUMAN             Reviewed;         369 AA.
AC   Q9BZ68; A1A4X4;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 2.
DT   13-SEP-2023, entry version 105.
DE   RecName: Full=Putative FERM domain-containing protein FRMD8P1;
DE   AltName: Full=FERM domain-containing 8 pseudogene 1;
GN   Name=FRMD8P1; ORFNames=FKSG43;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Wang Y.-G., Gong L.;
RT   "Cloning and characterization of FKSG43, a novel gene located on human
RT   chromosome Xq12.1-13.";
RL   Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- CAUTION: Could be the product of a pseudogene. Related to FRMD8.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG50294.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AF334945; AAG50294.1; ALT_SEQ; mRNA.
DR   EMBL; BC128150; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; Q9BZ68; -.
DR   SMR; Q9BZ68; -.
DR   IntAct; Q9BZ68; 1.
DR   BioMuta; HGNC:24690; -.
DR   DMDM; 269849595; -.
DR   jPOST; Q9BZ68; -.
DR   MassIVE; Q9BZ68; -.
DR   MaxQB; Q9BZ68; -.
DR   PeptideAtlas; Q9BZ68; -.
DR   AGR; HGNC:24690; -.
DR   GeneCards; FRMD8P1; -.
DR   HGNC; HGNC:24690; FRMD8P1.
DR   neXtProt; NX_Q9BZ68; -.
DR   InParanoid; Q9BZ68; -.
DR   PathwayCommons; Q9BZ68; -.
DR   SignaLink; Q9BZ68; -.
DR   Pharos; Q9BZ68; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q9BZ68; Protein.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR13283:SF12; FERM DOMAIN-CONTAINING PROTEIN FRMD8P1-RELATED; 1.
DR   PANTHER; PTHR13283; KREV INTERACTION TRAPPED 1-RELATED; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..369
FT                   /note="Putative FERM domain-containing protein FRMD8P1"
FT                   /id="PRO_0000295777"
FT   DOMAIN          30..369
FT                   /note="FERM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00084"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   369 AA;  41136 MW;  4E38687E625F3AD2 CRC64;
     MDGTEGSVGQ PGPTERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLRAHELHCA
     VREVLKLPDI ALDVFALWLV SPLLEVQLKP KNQPYKLGRQ WPELLLRFTS APDDDVAMDE
     PFLQFRRNVF FPKGRELQIP DEEVLRLLYE EAKGNVLAAR YLCDVEDCEA LGALVCRVQL
     VTYQPDWPAA CDLREKLDSF LPAHLCKRGQ GLFAALRGRG ARAGPGEQSL LNAYRKVQEV
     SSDGGCEAAL GTHYRAYLLK CHKLPFYGCA FFHGEVDKPA QGFLHRGGRK SVSVAISLEG
     VHVVDSREKH VLLGLCFQEL SWDHTSPEEE EPILWLEFDR DSGVTPVNKL LKIYSKQAEL
     MSSLIEYCI
//