Q9BZ68 (FR8P1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative FERM domain-containing protein FRMD8P1

Alternative name(s):
FERM domain-containing 8 pseudogene 1

Gene names

Name:	FRMD8P1
ORF Names:	FKSG43

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Sequence similarities	Contains 1 FERM domain.
Caution	Could be the product of a pseudogene. Related to FRMD8.
Sequence caution	The sequence AAG50294.1 differs from that shown. Reason: Erroneous termination at position 370. Translated as stop.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cytoskeleton Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 369	369	Putative FERM domain-containing protein FRMD8P1		PRO_0000295777
Regions
	Domain	30 – 369	340	FERM

Sequences

	Sequence		Length	Mass (Da)
	Q9BZ68 [UniParc]. Last modified November 24, 2009. Version 2. Checksum: 4E38687E625F3AD2	FASTA	369	41,136
	10 20 30 40 50 60 MDGTEGSVGQ PGPTERSHRS SVSSVGARAA DVLVYLADDT VVPLAVENLP SLRAHELHCA 70 80 90 100 110 120 VREVLKLPDI ALDVFALWLV SPLLEVQLKP KNQPYKLGRQ WPELLLRFTS APDDDVAMDE 130 140 150 160 170 180 PFLQFRRNVF FPKGRELQIP DEEVLRLLYE EAKGNVLAAR YLCDVEDCEA LGALVCRVQL 190 200 210 220 230 240 VTYQPDWPAA CDLREKLDSF LPAHLCKRGQ GLFAALRGRG ARAGPGEQSL LNAYRKVQEV 250 260 270 280 290 300 SSDGGCEAAL GTHYRAYLLK CHKLPFYGCA FFHGEVDKPA QGFLHRGGRK SVSVAISLEG 310 320 330 340 350 360 VHVVDSREKH VLLGLCFQEL SWDHTSPEEE EPILWLEFDR DSGVTPVNKL LKIYSKQAEL MSSLIEYCI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of FKSG43, a novel gene located on human chromosome Xq12.1-13." Wang Y.-G., Gong L. Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF334945 mRNA. Translation: AAG50294.1. Sequence problems. BC128150 mRNA. No translation available.
IPI	IPI00012481.
UniGene	Hs.652967.
3D structure databases
ProteinModelPortal	Q9BZ68.
SMR	Q9BZ68. Positions 61-322.
ModBase	Search...
Polymorphism databases
DMDM	269849595.
Proteomic databases
PaxDb	Q9BZ68.
PRIDE	Q9BZ68.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	uc022bye.1. human.
Organism-specific databases
GeneCards	GC0XM064772.
HGNC	HGNC:24690. FRMD8P1.
HPA	HPA002861.
neXtProt	NX_Q9BZ68.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG296493.
HOVERGEN	HBG104171.
InParanoid	Q9BZ68.
OrthoDB	EOG4K3KWB.
Gene expression databases
Genevestigator	Q9BZ68.
Family and domain databases
Gene3D	1.20.80.10. 1 hit.
InterPro	IPR019749. Band_41_domain. IPR014352. FERM/acyl-CoA-bd_prot_3-hlx. IPR019748. FERM_central. IPR000299. FERM_domain. [Graphical view]
Pfam	PF00373. FERM_M. 1 hit. [Graphical view]
SMART	SM00295. B41. 1 hit. [Graphical view]
SUPFAM	SSF47031. FERM_3-hlx. 1 hit.
PROSITE	PS00660. FERM_1. False negative. PS00661. FERM_2. False negative. PS50057. FERM_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35541718.

Entry information

Entry name

FR8P1_HUMAN

Accession

Primary (citable) accession number: Q9BZ68
Secondary accession number(s): A1A4X4

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 24, 2007
Last sequence update:	November 24, 2009
Last modified:	May 1, 2013
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.