##gff-version 3
Q9BYZ6	UniProtKB	Chain	1	727	.	.	.	ID=PRO_0000198962;Note=Rho-related BTB domain-containing protein 2	
Q9BYZ6	UniProtKB	Domain	266	442	.	.	.	Note=BTB 1;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00037	
Q9BYZ6	UniProtKB	Domain	500	567	.	.	.	Note=BTB 2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00037	
Q9BYZ6	UniProtKB	Region	1	210	.	.	.	Note=Rho-like	
Q9BYZ6	UniProtKB	Region	304	333	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9BYZ6	UniProtKB	Region	703	727	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q9BYZ6	UniProtKB	Binding site	21	28	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9BYZ6	UniProtKB	Binding site	84	88	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9BYZ6	UniProtKB	Binding site	140	143	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9BYZ6	UniProtKB	Alternative sequence	1	1	.	.	.	ID=VSP_054098;Note=In isoform 2. M->MQAWRKGPDGPQKTSSDSMSRLM;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q9BYZ6	UniProtKB	Alternative sequence	1	1	.	.	.	ID=VSP_054099;Note=In isoform 3. M->MKARSRLM;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9BYZ6	UniProtKB	Natural variant	452	452	.	.	.	ID=VAR_080812;Note=In DEE64%3B reduced RHOBTB2 proteasomal degradation%3B does not affect interaction with CUL3. A->G;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29276004;Dbxref=dbSNP:rs1554504656,PMID:29276004	
Q9BYZ6	UniProtKB	Natural variant	461	461	.	.	.	ID=VAR_080813;Note=In DEE64%3B reduced RHOBTB2 proteasomal degradation%3B does not affect interaction with CUL3. R->H;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:29276004,ECO:0000269|PubMed:29768694;Dbxref=dbSNP:rs1554504663,PMID:29276004,PMID:29768694	
Q9BYZ6	UniProtKB	Natural variant	485	485	.	.	.	ID=VAR_080814;Note=In DEE64%3B decreased proteasomal degradation%3B does not affect interaction with CUL3. R->C;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29768694;Dbxref=dbSNP:rs1563292586,PMID:29768694	
Q9BYZ6	UniProtKB	Natural variant	488	488	.	.	.	ID=VAR_079030;Note=In DEE64%3B also found in a patient with Rett syndrome-like phenotype. N->D;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:26740508,ECO:0000269|PubMed:29276004;Dbxref=dbSNP:rs1554504678,PMID:26740508,PMID:29276004	
Q9BYZ6	UniProtKB	Natural variant	489	489	.	.	.	ID=VAR_080815;Note=In DEE64%3B reduced RHOBTB2 proteasomal degradation%3B does not affect interaction with CUL3. R->Q;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:29276004,ECO:0000269|PubMed:29768694;Dbxref=dbSNP:rs1554504684,PMID:29276004,PMID:29768694	
Q9BYZ6	UniProtKB	Natural variant	489	489	.	.	.	ID=VAR_080816;Note=In DEE64. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29276004;Dbxref=dbSNP:rs1554504681,PMID:29276004	
Q9BYZ6	UniProtKB	Mutagenesis	284	284	.	.	.	Note=Results in decreased interaction with CUL3. Y->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:29768694;Dbxref=PMID:29768694	
Q9BYZ6	UniProtKB	Sequence conflict	255	255	.	.	.	Note=C->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q9BYZ6	UniProtKB	Sequence conflict	269	269	.	.	.	Note=I->F;Ontology_term=ECO:0000305;evidence=ECO:0000305