SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9BYZ0

- Q9BYZ0_HUMAN

UniProt

Q9BYZ0 - Q9BYZ0_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Beta-2 adrenergic receptor

Gene
ADRB2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. beta2-adrenergic receptor activity Source: Ensembl

GO - Biological processi

  1. adenylate cyclase-activating G-protein coupled receptor signaling pathway Source: Ensembl
  2. bone resorption Source: Ensembl
  3. brown fat cell differentiation Source: Ensembl
  4. diet induced thermogenesis Source: Ensembl
  5. heat generation Source: Ensembl
  6. negative regulation of multicellular organism growth Source: Ensembl
  7. negative regulation of smooth muscle contraction Source: Ensembl
  8. positive regulation of bone mineralization Source: Ensembl
  9. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  10. regulation of sodium ion transport Source: Ensembl
  11. regulation of vasodilation Source: InterPro
  12. response to cold Source: Ensembl
  13. vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-2 adrenergic receptorImported
Gene namesi
Name:ADRB2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. integral component of membrane Source: UniProtKB-KW
  3. nucleus Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9BYZ0.

Expressioni

Gene expression databases

ArrayExpressiQ9BYZ0.
BgeeiQ9BYZ0.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ9BYZ0.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOVERGENiHBG106962.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000332. ADRB2_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24248:SF21. PTHR24248:SF21. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00562. ADRENRGCB2AR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9BYZ0-1 [UniParc]FASTAAdd to Basket

« Hide

VLVITAIAKF ERLQTVTNYF ITSLACADLV MGLAVVPFGA AHILMKMWTF    50
GNFWCEFWTS IDVLCVTASI ETLCVIAVDR YFAITSPFKY QSLLTKNKAR 100
VIILMVWIVS GLTSFLPIQM HWYRATHQEA INCYANETCC DFFTNQAYAI 150
ASSIVSFYVP LVIMVFVYSR VFQEAKRQLQ KIDKSEGRFH VQNLSQVEQD 200
GRTGHGLRRS SKFCLKEHKA LKTLGIIMGT FTLCWLPFFI VNIVHVIQDN 250
LIRKEVYILL NWIGYVNSGF NPLIY 275
Length:275
Mass (Da):31,547
Last modified:June 1, 2001 - v1
Checksum:i5CBB37404B7ACBE7
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei275 – 2751Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011291 Genomic DNA. Translation: AAG35451.1.
UniGeneiHs.2551.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY011291 Genomic DNA. Translation: AAG35451.1 .
UniGenei Hs.2551.

3D structure databases

ProteinModelPortali Q9BYZ0.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q9BYZ0.

Protein family/group databases

GPCRDBi Search...

Proteomic databases

PRIDEi Q9BYZ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

H-InvDB HIX0164423.

Phylogenomic databases

HOVERGENi HBG106962.

Gene expression databases

ArrayExpressi Q9BYZ0.
Bgeei Q9BYZ0.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000332. ADRB2_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
PANTHERi PTHR24248:SF21. PTHR24248:SF21. 1 hit.
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00562. ADRENRGCB2AR.
PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular phylogenetics and the origins of placental mammals."
    Murphy W.J., Eizirik E., Johnson W.E., Zhang Y.P., Ryder O.A., O'Brien S.J.
    Nature 409:614-618(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9BYZ0_HUMAN
AccessioniPrimary (citable) accession number: Q9BYZ0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi