Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9BYZ0 (Q9BYZ0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:ADRB2 EMBL AAG35451.1
OrganismHomo sapiens (Human) EMBL AAG35451.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length275 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
   Cellular componentMembrane
   DomainTransmembrane RuleBase RU000688
   Molecular functionG-protein coupled receptor RuleBase RU000688
Receptor
Transducer
Gene Ontology (GO)
   Biological_processadenylate cyclase-activating G-protein coupled receptor signaling pathway

Inferred from electronic annotation. Source: Ensembl

bone resorption

Inferred from electronic annotation. Source: Ensembl

brown fat cell differentiation

Inferred from electronic annotation. Source: Ensembl

diet induced thermogenesis

Inferred from electronic annotation. Source: Ensembl

heat generation

Inferred from electronic annotation. Source: Ensembl

negative regulation of multicellular organism growth

Inferred from electronic annotation. Source: Ensembl

negative regulation of smooth muscle contraction

Inferred from electronic annotation. Source: Ensembl

positive regulation of bone mineralization

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

regulation of sodium ion transport

Inferred from electronic annotation. Source: Ensembl

regulation of vasodilation

Inferred from electronic annotation. Source: InterPro

response to cold

Inferred from electronic annotation. Source: Ensembl

vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentapical plasma membrane

Inferred from electronic annotation. Source: Ensembl

integral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

nucleus

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionbeta2-adrenergic receptor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAG35451.1
Non-terminal residue2751 EMBL AAG35451.1

Sequences

Sequence LengthMass (Da)Tools
Q9BYZ0 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 5CBB37404B7ACBE7

FASTA27531,547
        10         20         30         40         50         60 
VLVITAIAKF ERLQTVTNYF ITSLACADLV MGLAVVPFGA AHILMKMWTF GNFWCEFWTS 

        70         80         90        100        110        120 
IDVLCVTASI ETLCVIAVDR YFAITSPFKY QSLLTKNKAR VIILMVWIVS GLTSFLPIQM 

       130        140        150        160        170        180 
HWYRATHQEA INCYANETCC DFFTNQAYAI ASSIVSFYVP LVIMVFVYSR VFQEAKRQLQ 

       190        200        210        220        230        240 
KIDKSEGRFH VQNLSQVEQD GRTGHGLRRS SKFCLKEHKA LKTLGIIMGT FTLCWLPFFI 

       250        260        270 
VNIVHVIQDN LIRKEVYILL NWIGYVNSGF NPLIY 

« Hide

References

[1]"Molecular phylogenetics and the origins of placental mammals."
Murphy W.J., Eizirik E., Johnson W.E., Zhang Y.P., Ryder O.A., O'Brien S.J.
Nature 409:614-618(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY011291 Genomic DNA. Translation: AAG35451.1.
UniGeneHs.2551.

3D structure databases

ProteinModelPortalQ9BYZ0.
ModBaseSearch...
MobiDBSearch...

Chemistry

BindingDBQ9BYZ0.

Protein family/group databases

GPCRDBSearch...

Proteomic databases

PRIDEQ9BYZ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

H-InvDBHIX0164423.

Phylogenomic databases

HOVERGENHBG106962.

Gene expression databases

ArrayExpressQ9BYZ0.
BgeeQ9BYZ0.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000332. ADRB2_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERPTHR24248:SF21. PTHR24248:SF21. 1 hit.
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00562. ADRENRGCB2AR.
PR00237. GPCRRHODOPSN.
PROSITEPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9BYZ0_HUMAN
AccessionPrimary (citable) accession number: Q9BYZ0
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.