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Protein

Sterile alpha motif domain-containing protein 10

Gene

SAMD10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ9BYL1.

Names & Taxonomyi

Protein namesi
Recommended name:
Sterile alpha motif domain-containing protein 10
Short name:
SAM domain-containing protein 10
Gene namesi
Name:SAMD10
Synonyms:C20orf136
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:16129. SAMD10.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25678.

Polymorphism and mutation databases

BioMutaiSAMD10.
DMDMi26392486.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202Sterile alpha motif domain-containing protein 10PRO_0000097568Add
BLAST

Proteomic databases

PaxDbiQ9BYL1.
PeptideAtlasiQ9BYL1.
PRIDEiQ9BYL1.

PTM databases

PhosphoSiteiQ9BYL1.

Expressioni

Gene expression databases

BgeeiQ9BYL1.
CleanExiHS_SAMD10.
ExpressionAtlasiQ9BYL1. baseline and differential.
GenevisibleiQ9BYL1. HS.

Organism-specific databases

HPAiHPA040973.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000358902.

Structurei

3D structure databases

ProteinModelPortaliQ9BYL1.
SMRiQ9BYL1. Positions 113-186.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini118 – 18467SAMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SAM (sterile alpha motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IJ7W. Eukaryota.
ENOG41128Z9. LUCA.
GeneTreeiENSGT00390000008161.
HOGENOMiHOG000132938.
HOVERGENiHBG079163.
InParanoidiQ9BYL1.
OMAiTWHDGRS.
OrthoDBiEOG7WT42S.
PhylomeDBiQ9BYL1.
TreeFamiTF325918.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BYL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTELRSKLS PPRGRAGAVR AGFGERRDVD ATAHFSFCRT LLEHTVSAES
60 70 80 90 100
IPCHLPRTPG TSLTWHDSRS QRAASSRPIK LLQQPGTDTP QGRLYSDHYG
110 120 130 140 150
LYHTSPSLGG LTRPVVLWSQ QDVCKWLKKH CPHNYLVYVE AFSQHAITGR
160 170 180 190 200
ALLRLNAEKL QRMGLAQEAQ RQEVLQQVLR LQVREEGRSL QLLSQASFGK

MS
Length:202
Mass (Da):22,770
Last modified:June 1, 2001 - v1
Checksum:iDF2678F090A3E946
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118506 Genomic DNA. Translation: CAC28315.1.
BC067362 mRNA. Translation: AAH67362.1.
CCDSiCCDS13549.1.
RefSeqiNP_542188.1. NM_080621.4.
UniGeneiHs.27189.

Genome annotation databases

EnsembliENST00000369886; ENSP00000358902; ENSG00000130590.
GeneIDi140700.
KEGGihsa:140700.
UCSCiuc002yhm.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL118506 Genomic DNA. Translation: CAC28315.1.
BC067362 mRNA. Translation: AAH67362.1.
CCDSiCCDS13549.1.
RefSeqiNP_542188.1. NM_080621.4.
UniGeneiHs.27189.

3D structure databases

ProteinModelPortaliQ9BYL1.
SMRiQ9BYL1. Positions 113-186.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000358902.

PTM databases

PhosphoSiteiQ9BYL1.

Polymorphism and mutation databases

BioMutaiSAMD10.
DMDMi26392486.

Proteomic databases

PaxDbiQ9BYL1.
PeptideAtlasiQ9BYL1.
PRIDEiQ9BYL1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000369886; ENSP00000358902; ENSG00000130590.
GeneIDi140700.
KEGGihsa:140700.
UCSCiuc002yhm.2. human.

Organism-specific databases

CTDi140700.
GeneCardsiSAMD10.
HGNCiHGNC:16129. SAMD10.
HPAiHPA040973.
neXtProtiNX_Q9BYL1.
PharmGKBiPA25678.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJ7W. Eukaryota.
ENOG41128Z9. LUCA.
GeneTreeiENSGT00390000008161.
HOGENOMiHOG000132938.
HOVERGENiHBG079163.
InParanoidiQ9BYL1.
OMAiTWHDGRS.
OrthoDBiEOG7WT42S.
PhylomeDBiQ9BYL1.
TreeFamiTF325918.

Enzyme and pathway databases

SignaLinkiQ9BYL1.

Miscellaneous databases

ChiTaRSiSAMD10. human.
GenomeRNAii140700.
PROiQ9BYL1.

Gene expression databases

BgeeiQ9BYL1.
CleanExiHS_SAMD10.
ExpressionAtlasiQ9BYL1. baseline and differential.
GenevisibleiQ9BYL1. HS.

Family and domain databases

Gene3Di1.10.150.50. 1 hit.
InterProiIPR001660. SAM.
IPR013761. SAM/pointed.
[Graphical view]
PfamiPF07647. SAM_2. 1 hit.
[Graphical view]
SMARTiSM00454. SAM. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
PROSITEiPS50105. SAM_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiSAM10_HUMAN
AccessioniPrimary (citable) accession number: Q9BYL1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: June 1, 2001
Last modified: July 6, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.