Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9BYD9

- ACTT3_HUMAN

UniProt

Q9BYD9 - ACTT3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Actin-related protein T3

Gene

ACTRT3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ9BYD9.

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein T3
Short name:
ARP-T3
Alternative name(s):
Actin-related protein M1
Gene namesi
Name:ACTRT3
Synonyms:ARPM1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 3

Organism-specific databases

HGNCiHGNC:24022. ACTRT3.

Subcellular locationi

Cytoplasmcytoskeleton By similarity. Cytoplasm By similarity. Nucleus By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. cytoskeleton Source: UniProtKB-KW
  3. male germ cell nucleus Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 372372Actin-related protein T3PRO_0000089142Add
BLAST

Proteomic databases

PaxDbiQ9BYD9.
PRIDEiQ9BYD9.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

BgeeiQ9BYD9.
GenevestigatoriQ9BYD9.

Organism-specific databases

HPAiHPA035817.
HPA035818.

Interactioni

Subunit structurei

Interacts with PFN3.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9BYD9.
SMRiQ9BYD9. Positions 8-372.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiCOG5277.
GeneTreeiENSGT00760000118957.
HOGENOMiHOG000233340.
HOVERGENiHBG003771.
InParanoidiQ9BYD9.
OMAiNIVHQRC.
OrthoDBiEOG708VZV.
PhylomeDBiQ9BYD9.
TreeFamiTF337161.

Family and domain databases

InterProiIPR004000. Actin-related.
IPR020902. Actin/actin-like_CS.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
PRINTSiPR00190. ACTIN.
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
PROSITEiPS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BYD9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNHCQLPVVI DNGSGMIKAG VAGCREPQFI YPNIIGRAKG QSRAAQGGLE
60 70 80 90 100
LCVGDQAQDW RSSLFISYPV ERGLITSWED MEIMWKHIYD YNLKLKPCDG
110 120 130 140 150
PVLITEPALN PLANRQQITE MFFEHLGVPA FYMSIQAVLA LFAAGFTTGL
160 170 180 190 200
VLNSGAGVTQ SVPIFEGYCL PHGVQQLDLA GLDLTNYLMV LMKNHGIMLL
210 220 230 240 250
SASDRKIVED IKESFCYVAM NYEEEMAKKP DCLEKVYQLP DGKVIQLHDQ
260 270 280 290 300
LFSCPEALFS PCHMNLEAPG IDKICFSSIM KCDTGLRNSF FSNIILAGGS
310 320 330 340 350
TSFPGLDKRL VKDIAKVAPA NTAVQVIAPP ERKISVWMGG SILASLSAFQ
360 370
DMWITAAEFK EVGPNIVHQR CF
Length:372
Mass (Da):41,008
Last modified:June 1, 2001 - v1
Checksum:i56413BCF02AA4794
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti78 – 781W → C in AAH07289. (PubMed:16641997)Curated
Sequence conflicti282 – 2821C → R in BAB70906. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti234 – 2341E → K.
Corresponds to variant rs2068178 [ dbSNP | Ensembl ].
VAR_055483

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB049117 mRNA. Translation: BAB39481.1.
AK055346 mRNA. Translation: BAB70906.1.
AC078802 Genomic DNA. No translation available.
BC007289 mRNA. Translation: AAH07289.1.
CCDSiCCDS3206.1.
RefSeqiNP_115876.3. NM_032487.4.
UniGeneiHs.135411.

Genome annotation databases

EnsembliENST00000330368; ENSP00000333037; ENSG00000184378.
GeneIDi84517.
KEGGihsa:84517.
UCSCiuc003ffs.2. human.

Polymorphism databases

DMDMi47116738.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB049117 mRNA. Translation: BAB39481.1 .
AK055346 mRNA. Translation: BAB70906.1 .
AC078802 Genomic DNA. No translation available.
BC007289 mRNA. Translation: AAH07289.1 .
CCDSi CCDS3206.1.
RefSeqi NP_115876.3. NM_032487.4.
UniGenei Hs.135411.

3D structure databases

ProteinModelPortali Q9BYD9.
SMRi Q9BYD9. Positions 8-372.
ModBasei Search...
MobiDBi Search...

Polymorphism databases

DMDMi 47116738.

Proteomic databases

PaxDbi Q9BYD9.
PRIDEi Q9BYD9.

Protocols and materials databases

DNASUi 84517.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000330368 ; ENSP00000333037 ; ENSG00000184378 .
GeneIDi 84517.
KEGGi hsa:84517.
UCSCi uc003ffs.2. human.

Organism-specific databases

CTDi 84517.
GeneCardsi GC03M169497.
HGNCi HGNC:24022. ACTRT3.
HPAi HPA035817.
HPA035818.
MIMi 608534. gene.
neXtProti NX_Q9BYD9.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG5277.
GeneTreei ENSGT00760000118957.
HOGENOMi HOG000233340.
HOVERGENi HBG003771.
InParanoidi Q9BYD9.
OMAi NIVHQRC.
OrthoDBi EOG708VZV.
PhylomeDBi Q9BYD9.
TreeFami TF337161.

Enzyme and pathway databases

SignaLinki Q9BYD9.

Miscellaneous databases

GenomeRNAii 84517.
NextBioi 74326.
PROi Q9BYD9.
SOURCEi Search...

Gene expression databases

Bgeei Q9BYD9.
Genevestigatori Q9BYD9.

Family and domain databases

InterProi IPR004000. Actin-related.
IPR020902. Actin/actin-like_CS.
[Graphical view ]
PANTHERi PTHR11937. PTHR11937. 1 hit.
Pfami PF00022. Actin. 1 hit.
[Graphical view ]
PRINTSi PR00190. ACTIN.
SMARTi SM00268. ACTIN. 1 hit.
[Graphical view ]
PROSITEi PS01132. ACTINS_ACT_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of two cDNAs for human actin-related proteins (Arps) that have remarkable similarity to conventional actin."
    Harata M., Nishimori K., Hatta S.
    Biochim. Biophys. Acta 1522:130-133(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.
  3. "The DNA sequence, annotation and analysis of human chromosome 3."
    Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J.
    , Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B., Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H., Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J., Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.
    Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Colon.

Entry informationi

Entry nameiACTT3_HUMAN
AccessioniPrimary (citable) accession number: Q9BYD9
Secondary accession number(s): Q96IS0, Q96NJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3