Q9BYD2 (RM09_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
39S ribosomal protein L9, mitochondrial
Short name=L9mt
Short name=MRP-L9

Gene names

Name:

MRPL9

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	267 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion.
Sequence similarities	Belongs to the ribosomal protein L9P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Coding sequence diversity	Polymorphism
Domain	Transit peptide
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Non-traceable author statement PubMed 11543634. Source: UniProtKB
Cellular_component	mitochondrial ribosome Non-traceable author statement PubMed 11543634. Source: UniProtKB
Molecular_function	structural constituent of ribosome Non-traceable author statement PubMed 11543634. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 267		39S ribosomal protein L9, mitochondrial		PRO_0000030550
Natural variations
	Natural variant	67	1	E → G. Corresponds to variant rs7007 [ dbSNP | Ensembl ].		VAR_028136
	Natural variant	210	1	E → A. Ref.1 Corresponds to variant rs8480 [ dbSNP | Ensembl ].		VAR_028137

Sequences

	Sequence		Length	Mass (Da)
	Q9BYD2 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 3468214224FBD1B4	FASTA	267	30,243
	10 20 30 40 50 60 MAAPVVTAPG RALLRAGAGR LLRGGVQELL RPRHEGNAPD LACNFSLSQN RGTVIVERWW 70 80 90 100 110 120 KVPLAGEGRK PRLHRRHRVY KLVEDTKHRP KENLELILTQ SVENVGVRGD LVSVKKSLGR 130 140 150 160 170 180 NRLLPQGLAV YASPENKKLF EEEKLLRQEG KLEKIQTKAG EATVKFLKSC RLEVGMKNNV 190 200 210 220 230 240 KWELNPEIVA RHFFKNLGVV VAPHTLKLPE EPITRWGEYW CEVTVNGLDT VRVPMSVVNF 250 260 EKPKTKRYKY WLAQQAAKAM APTSPQI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria." Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K. J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], VARIANT ALA-210.
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]	"The DNA sequence and biological annotation of human chromosome 1." Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K. , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R. Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung.
[6]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB049636 mRNA. Translation: BAB40841.1. AK315459 mRNA. Translation: BAG37846.1. AL589765 Genomic DNA. Translation: CAI17171.1. CH471121 Genomic DNA. Translation: EAW53415.1. BC004517 mRNA. Translation: AAH04517.1.
IPI	IPI00307409.
RefSeq	NP_113608.1. NM_031420.2.
UniGene	Hs.288936.
3D structure databases
ProteinModelPortal	Q9BYD2.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BYD2. 4 interactions.
MINT	MINT-1392474.
STRING	9606.ENSP00000357823.
PTM databases
PhosphoSite	Q9BYD2.
Polymorphism databases
DMDM	209572671.
Proteomic databases
PaxDb	Q9BYD2.
PRIDE	Q9BYD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000368830; ENSP00000357823; ENSG00000143436.
GeneID	65005.
KEGG	hsa:65005.
UCSC	uc001eyv.3. human.
Organism-specific databases
CTD	65005.
GeneCards	GC01M151732.
HGNC	HGNC:14277. MRPL9.
HPA	HPA008579.
MIM	611824. gene.
neXtProt	NX_Q9BYD2.
PharmGKB	PA30991.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG311734.
HOGENOM	HOG000247066.
HOVERGEN	HBG002704.
InParanoid	Q9BYD2.
KO	K02939.
OMA	ATVKFLK.
OrthoDB	EOG480HXQ.
PhylomeDB	Q9BYD2.
Gene expression databases
ArrayExpress	Q9BYD2.
Bgee	Q9BYD2.
CleanEx	HS_MRPL9.
Genevestigator	Q9BYD2.
GermOnline	ENSG00000143436. Homo sapiens.
Family and domain databases
Gene3D	3.40.5.10. 1 hit.
InterPro	IPR000244. Ribosomal_L9. IPR009027. Ribosomal_L9/RNase_H1_N. IPR020070. Ribosomal_L9_N. [Graphical view]
PANTHER	PTHR21368. PTHR21368. 1 hit.
Pfam	PF01281. Ribosomal_L9_N. 1 hit. [Graphical view]
SUPFAM	SSF55658. L9_N_like. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	MRPL9. human.
GenomeRNAi	65005.
NextBio	67188.
SOURCE	Search...

Entry information

Entry name

RM09_HUMAN

Accession

Primary (citable) accession number: Q9BYD2
Secondary accession number(s): B2RD99, Q5SZR2, Q9BSW8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 13, 2001
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 101 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.