Q9BYD1 (RM13_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
39S ribosomal protein L13, mitochondrial
Short name=L13mt
Short name=MRP-L13

Gene names

Name:

MRPL13

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	178 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Interacts with OXA1L By similarity.
Subcellular location	Mitochondrion Ref.1.
Sequence similarities	Belongs to the ribosomal protein L13P family.
Sequence caution	The sequence AAF17202.1 differs from that shown. Reason: Frameshift at position 160.

Ontologies

Keywords
Cellular component	Mitochondrion
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Non-traceable author statement Ref.1. Source: UniProtKB
Cellular_component	mitochondrial large ribosomal subunit Non-traceable author statement Ref.1. Source: UniProtKB
Molecular_function	structural constituent of ribosome Non-traceable author statement Ref.1. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 178	178	39S ribosomal protein L13, mitochondrial		PRO_0000133793

Sequences

	Sequence		Length	Mass (Da)
	Q9BYD1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: AF4FD524CC234D52	FASTA	178	20,692
	10 20 30 40 50 60 MSSFSRAPQQ WATFARIWYL LDGKMQPPGK LAAMASIRLQ GLHKPVYHAL SDCGDHVVIM 70 80 90 100 110 120 NTRHIAFSGN KWEQKVYSSH TGYPGGFRQV TAAQLHLRDP VAIVKLAIYG MLPKNLHRRT 130 140 150 160 170 MMERLHLFPD EYIPEDILKN LVEELPQPRK IPKRLDEYTQ EEIDAFPRLW TPPEDYRL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria." Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K. J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION.
[2]	"A novel gene expressed in human adrenal gland." Ren S., Jiang C., Huang C., Li Y., Lin W., Zhou J., Yu Y., Xu S., Wang Y., Han Z., Chen Z., Fu G. Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Adrenal gland.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Cerebellum.
[4]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain and Placenta.
[6]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB049640 mRNA. Translation: BAB40845.1. AF112214 mRNA. Translation: AAF17202.1. Frameshift. AK311924 mRNA. Translation: BAG34865.1. CH471060 Genomic DNA. Translation: EAW92004.1. BC009190 mRNA. Translation: AAH09190.1. BC021744 mRNA. Translation: AAH21744.1.
IPI	IPI00022403.
RefSeq	NP_054797.2. NM_014078.5.
UniGene	Hs.333823.
3D structure databases
ProteinModelPortal	Q9BYD1.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BYD1. 2 interactions.
STRING	9606.ENSP00000306548.
PTM databases
PhosphoSite	Q9BYD1.
Polymorphism databases
DMDM	22257023.
Proteomic databases
PaxDb	Q9BYD1.
PRIDE	Q9BYD1.
Protocols and materials databases
DNASU	28998.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000306185; ENSP00000306548; ENSG00000172172.
GeneID	28998.
KEGG	hsa:28998.
UCSC	uc003ypa.3. human.
Organism-specific databases
CTD	28998.
GeneCards	GC08M121477.
HGNC	HGNC:14278. MRPL13.
MIM	610200. gene.
neXtProt	NX_Q9BYD1.
PharmGKB	PA30942.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0102.
HOGENOM	HOG000225288.
HOVERGEN	HBG036111.
InParanoid	Q9BYD1.
KO	K02871.
OMA	VQQWATF.
OrthoDB	EOG4Z8XXJ.
PhylomeDB	Q9BYD1.
Gene expression databases
ArrayExpress	Q9BYD1.
Bgee	Q9BYD1.
CleanEx	HS_MRPL13.
Genevestigator	Q9BYD1.
GermOnline	ENSG00000172172. Homo sapiens.
Family and domain databases
Gene3D	3.90.1180.10. 1 hit.
InterPro	IPR005822. Ribosomal_L13. IPR005823. Ribosomal_L13_bac-type. IPR023563. Ribosomal_L13_CS. IPR023564. Ribosomal_L13_dom. [Graphical view]
PANTHER	PTHR11545. PTHR11545. 1 hit.
Pfam	PF00572. Ribosomal_L13. 1 hit. [Graphical view]
PIRSF	PIRSF002181. Ribosomal_L13. 1 hit.
SUPFAM	SSF52161. Ribosomal_L13. 1 hit.
TIGRFAMs	TIGR01066. rplM_bact. 1 hit.
PROSITE	PS00783. RIBOSOMAL_L13. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	28998.
NextBio	51932.
SOURCE	Search...

Entry information

Entry name

RM13_HUMAN

Accession

Primary (citable) accession number: Q9BYD1
Secondary accession number(s): B2R4R8, Q9UI04

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 13, 2002
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 99 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.