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Q9BYD1

- RM13_HUMAN

UniProt

Q9BYD1 - RM13_HUMAN

Protein

39S ribosomal protein L13, mitochondrial

Gene

MRPL13

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 112 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. poly(A) RNA binding Source: UniProtKB
    2. protein binding Source: UniProtKB
    3. structural constituent of ribosome Source: UniProtKB

    GO - Biological processi

    1. translation Source: UniProtKB

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    39S ribosomal protein L13, mitochondrial
    Short name:
    L13mt
    Short name:
    MRP-L13
    Gene namesi
    Name:MRPL13
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 8

    Organism-specific databases

    HGNCiHGNC:14278. MRPL13.

    Subcellular locationi

    Mitochondrion 1 Publication

    GO - Cellular componenti

    1. mitochondrial large ribosomal subunit Source: UniProtKB
    2. mitochondrial ribosome Source: UniProtKB

    Keywords - Cellular componenti

    Mitochondrion

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA30942.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 17817839S ribosomal protein L13, mitochondrialPRO_0000133793Add
    BLAST

    Proteomic databases

    MaxQBiQ9BYD1.
    PaxDbiQ9BYD1.
    PRIDEiQ9BYD1.

    PTM databases

    PhosphoSiteiQ9BYD1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9BYD1.
    BgeeiQ9BYD1.
    CleanExiHS_MRPL13.
    GenevestigatoriQ9BYD1.

    Organism-specific databases

    HPAiHPA060899.

    Interactioni

    Subunit structurei

    Interacts with OXA1L.By similarity

    Protein-protein interaction databases

    BioGridi118817. 35 interactions.
    IntActiQ9BYD1. 3 interactions.
    MINTiMINT-3064087.
    STRINGi9606.ENSP00000306548.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9BYD1.
    SMRiQ9BYD1. Positions 1-147.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L13P family.Curated

    Phylogenomic databases

    eggNOGiCOG0102.
    HOGENOMiHOG000225288.
    HOVERGENiHBG036111.
    InParanoidiQ9BYD1.
    KOiK02871.
    OMAiFARTWHI.
    PhylomeDBiQ9BYD1.
    TreeFamiTF312914.

    Family and domain databases

    Gene3Di3.90.1180.10. 1 hit.
    HAMAPiMF_01366. Ribosomal_L13.
    InterProiIPR005822. Ribosomal_L13.
    IPR005823. Ribosomal_L13_bac-type.
    IPR023563. Ribosomal_L13_CS.
    IPR023564. Ribosomal_L13_dom.
    [Graphical view]
    PANTHERiPTHR11545. PTHR11545. 1 hit.
    PfamiPF00572. Ribosomal_L13. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002181. Ribosomal_L13. 1 hit.
    SUPFAMiSSF52161. SSF52161. 1 hit.
    TIGRFAMsiTIGR01066. rplM_bact. 1 hit.
    PROSITEiPS00783. RIBOSOMAL_L13. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9BYD1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSFSRAPQQ WATFARIWYL LDGKMQPPGK LAAMASIRLQ GLHKPVYHAL    50
    SDCGDHVVIM NTRHIAFSGN KWEQKVYSSH TGYPGGFRQV TAAQLHLRDP 100
    VAIVKLAIYG MLPKNLHRRT MMERLHLFPD EYIPEDILKN LVEELPQPRK 150
    IPKRLDEYTQ EEIDAFPRLW TPPEDYRL 178
    Length:178
    Mass (Da):20,692
    Last modified:June 1, 2001 - v1
    Checksum:iAF4FD524CC234D52
    GO

    Sequence cautioni

    The sequence AAF17202.1 differs from that shown. Reason: Frameshift at position 160.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB049640 mRNA. Translation: BAB40845.1.
    AF112214 mRNA. Translation: AAF17202.1. Frameshift.
    AK311924 mRNA. Translation: BAG34865.1.
    CH471060 Genomic DNA. Translation: EAW92004.1.
    BC009190 mRNA. Translation: AAH09190.1.
    BC021744 mRNA. Translation: AAH21744.1.
    CCDSiCCDS6332.1.
    RefSeqiNP_054797.2. NM_014078.5.
    UniGeneiHs.333823.

    Genome annotation databases

    EnsembliENST00000306185; ENSP00000306548; ENSG00000172172.
    GeneIDi28998.
    KEGGihsa:28998.
    UCSCiuc003ypa.3. human.

    Polymorphism databases

    DMDMi22257023.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB049640 mRNA. Translation: BAB40845.1 .
    AF112214 mRNA. Translation: AAF17202.1 . Frameshift.
    AK311924 mRNA. Translation: BAG34865.1 .
    CH471060 Genomic DNA. Translation: EAW92004.1 .
    BC009190 mRNA. Translation: AAH09190.1 .
    BC021744 mRNA. Translation: AAH21744.1 .
    CCDSi CCDS6332.1.
    RefSeqi NP_054797.2. NM_014078.5.
    UniGenei Hs.333823.

    3D structure databases

    ProteinModelPortali Q9BYD1.
    SMRi Q9BYD1. Positions 1-147.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 118817. 35 interactions.
    IntActi Q9BYD1. 3 interactions.
    MINTi MINT-3064087.
    STRINGi 9606.ENSP00000306548.

    PTM databases

    PhosphoSitei Q9BYD1.

    Polymorphism databases

    DMDMi 22257023.

    Proteomic databases

    MaxQBi Q9BYD1.
    PaxDbi Q9BYD1.
    PRIDEi Q9BYD1.

    Protocols and materials databases

    DNASUi 28998.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000306185 ; ENSP00000306548 ; ENSG00000172172 .
    GeneIDi 28998.
    KEGGi hsa:28998.
    UCSCi uc003ypa.3. human.

    Organism-specific databases

    CTDi 28998.
    GeneCardsi GC08M121477.
    HGNCi HGNC:14278. MRPL13.
    HPAi HPA060899.
    MIMi 610200. gene.
    neXtProti NX_Q9BYD1.
    PharmGKBi PA30942.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG0102.
    HOGENOMi HOG000225288.
    HOVERGENi HBG036111.
    InParanoidi Q9BYD1.
    KOi K02871.
    OMAi FARTWHI.
    PhylomeDBi Q9BYD1.
    TreeFami TF312914.

    Miscellaneous databases

    GenomeRNAii 28998.
    NextBioi 51932.
    PROi Q9BYD1.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9BYD1.
    Bgeei Q9BYD1.
    CleanExi HS_MRPL13.
    Genevestigatori Q9BYD1.

    Family and domain databases

    Gene3Di 3.90.1180.10. 1 hit.
    HAMAPi MF_01366. Ribosomal_L13.
    InterProi IPR005822. Ribosomal_L13.
    IPR005823. Ribosomal_L13_bac-type.
    IPR023563. Ribosomal_L13_CS.
    IPR023564. Ribosomal_L13_dom.
    [Graphical view ]
    PANTHERi PTHR11545. PTHR11545. 1 hit.
    Pfami PF00572. Ribosomal_L13. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002181. Ribosomal_L13. 1 hit.
    SUPFAMi SSF52161. SSF52161. 1 hit.
    TIGRFAMsi TIGR01066. rplM_bact. 1 hit.
    PROSITEi PS00783. RIBOSOMAL_L13. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
      Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
      J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION.
    2. "A novel gene expressed in human adrenal gland."
      Ren S., Jiang C., Huang C., Li Y., Lin W., Zhou J., Yu Y., Xu S., Wang Y., Han Z., Chen Z., Fu G.
      Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Adrenal gland.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Cerebellum.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Brain and Placenta.
    6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRM13_HUMAN
    AccessioniPrimary (citable) accession number: Q9BYD1
    Secondary accession number(s): B2R4R8, Q9UI04
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 13, 2002
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 112 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 8
      Human chromosome 8: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. Ribosomal proteins
      Ribosomal proteins families and list of entries
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3