Q9BYC8 (RM32_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
39S ribosomal protein L32, mitochondrial
Short name=L32mt
Short name=MRP-L32

Gene names

Name:	MRPL32
ORF Names:	HSPC283

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Mitochondrion.
Sequence similarities	Belongs to the ribosomal protein L32P family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	translation Non-traceable author statement Ref.4. Source: UniProtKB
Cellular_component	large ribosomal subunit Inferred from electronic annotation. Source: InterPro mitochondrial ribosome Non-traceable author statement Ref.4. Source: UniProtKB
Molecular_function	structural constituent of ribosome Non-traceable author statement Ref.4. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 188		39S ribosomal protein L32, mitochondrial		PRO_0000030513
Experimental info
	Sequence conflict	11 – 43	33	SPWSA…PSPPW → RRGLRPGECFETTGSDCYGS FRRAGRAFPVLRGV Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Q9BYC8 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 60164AD910AE3EFD	FASTA	188	21,405
	10 20 30 40 50 60 MALAMLVLVV SPWSAARGVL RNYWERLLRK LPQSRPGFPS PPWGPALAVQ GPAMFTEPAN 70 80 90 100 110 120 DTSGSKENSS LLDSIFWMAA PKNRRTIEVN RCRRRNPQKL IKVKNNIDVC PECGHLKQKH 130 140 150 160 170 180 VLCAYCYEKV CKETAEIRRQ IGKQEGGPFK APTIETVVLY TGETPSEQDQ GKRIIERDRK RPSWFTQN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria." Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K. J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lymph.
[3]	"Human partial CDS from CD34+ stem cells." Ye M., Zhang Q.-H., Zhou J., Shen Y., Wu X.-Y., Guan Z.Q., Wang L., Fan H.-Y., Mao Y.-F., Dai M., Huang Q.-H., Chen S.-J., Chen Z. Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-188. Tissue: Umbilical cord blood.
[4]	"The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders." Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T. Genomics 77:65-70(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 105-126.
[5]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB049649 mRNA. Translation: BAB40854.1. BC013147 mRNA. Translation: AAH13147.1. AF161401 mRNA. Translation: AAF28961.1. AB051343 Genomic DNA. Translation: BAB54933.1.
IPI	IPI00011077.
RefSeq	NP_114109.1. NM_031903.2.
UniGene	Hs.50252.
3D structure databases
ProteinModelPortal	Q9BYC8.
SMR	Q9BYC8. Positions 79-126.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000223324.
PTM databases
PhosphoSite	Q9BYC8.
Polymorphism databases
DMDM	22001923.
Proteomic databases
PaxDb	Q9BYC8.
PRIDE	Q9BYC8.
Protocols and materials databases
DNASU	64983.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000223324; ENSP00000223324; ENSG00000106591.
GeneID	64983.
KEGG	hsa:64983.
UCSC	uc003tia.3. human.
Organism-specific databases
CTD	64983.
GeneCards	GC07P042971.
HGNC	HGNC:14035. MRPL32.
HPA	HPA048965.
MIM	611839. gene.
neXtProt	NX_Q9BYC8.
PharmGKB	PA30963.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG297873.
HOGENOM	HOG000252980.
HOVERGEN	HBG036112.
InParanoid	Q9BYC8.
KO	K02911.
OMA	VPPWPAA.
OrthoDB	EOG4NS3CW.
PhylomeDB	Q9BYC8.
Gene expression databases
ArrayExpress	Q9BYC8.
Bgee	Q9BYC8.
CleanEx	HS_MRPL32.
Genevestigator	Q9BYC8.
GermOnline	ENSG00000106591. Homo sapiens.
Family and domain databases
InterPro	IPR002677. Ribosomal_L32p. [Graphical view]
Pfam	PF01783. Ribosomal_L32p. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	64983.
NextBio	67176.
SOURCE	Search...

Entry information

Entry name

RM32_HUMAN

Accession

Primary (citable) accession number: Q9BYC8
Secondary accession number(s): Q96Q68, Q9P098

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 26, 2002
Last sequence update:	June 1, 2001
Last modified:	April 3, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.