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Q9BYC8 (RM32_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 104. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
39S ribosomal protein L32, mitochondrial

Short name=L32mt
Short name=MRP-L32
Gene names
Name:MRPL32
ORF Names:HSPC283
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length188 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Mitochondrion.

Sequence similarities

Belongs to the ribosomal protein L32P family.

Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Non-traceable author statement Ref.4. Source: UniProtKB

   Cellular_componentlarge ribosomal subunit

Inferred from electronic annotation. Source: InterPro

mitochondrial ribosome

Non-traceable author statement Ref.4. Source: UniProtKB

   Molecular_functionpoly(A) RNA binding

Inferred from direct assay PubMed 22658674. Source: UniProtKB

structural constituent of ribosome

Non-traceable author statement Ref.4. Source: UniProtKB

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – ?Mitochondrion Potential
Chain? – 18839S ribosomal protein L32, mitochondrialPRO_0000030513

Experimental info

Sequence conflict11 – 4333SPWSA…PSPPW → RRGLRPGECFETTGSDCYGS FRRAGRAFPVLRGV Ref.3

Sequences

Sequence LengthMass (Da)Tools
Q9BYC8 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 60164AD910AE3EFD

FASTA18821,405
        10         20         30         40         50         60 
MALAMLVLVV SPWSAARGVL RNYWERLLRK LPQSRPGFPS PPWGPALAVQ GPAMFTEPAN 

        70         80         90        100        110        120 
DTSGSKENSS LLDSIFWMAA PKNRRTIEVN RCRRRNPQKL IKVKNNIDVC PECGHLKQKH 

       130        140        150        160        170        180 
VLCAYCYEKV CKETAEIRRQ IGKQEGGPFK APTIETVVLY TGETPSEQDQ GKRIIERDRK 


RPSWFTQN 

« Hide

References

« Hide 'large scale' references
[1]"Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Lymph.
[3]"Human partial CDS from CD34+ stem cells."
Ye M., Zhang Q.-H., Zhou J., Shen Y., Wu X.-Y., Guan Z.Q., Wang L., Fan H.-Y., Mao Y.-F., Dai M., Huang Q.-H., Chen S.-J., Chen Z.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-188.
Tissue: Umbilical cord blood.
[4]"The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders."
Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T.
Genomics 77:65-70(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 105-126.
[5]"Initial characterization of the human central proteome."
Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB049649 mRNA. Translation: BAB40854.1.
BC013147 mRNA. Translation: AAH13147.1.
AF161401 mRNA. Translation: AAF28961.1.
AB051343 Genomic DNA. Translation: BAB54933.1.
CCDSCCDS5468.1.
RefSeqNP_114109.1. NM_031903.2.
UniGeneHs.50252.

3D structure databases

ProteinModelPortalQ9BYC8.
SMRQ9BYC8. Positions 79-127.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122368. 29 interactions.
IntActQ9BYC8. 1 interaction.
MINTMINT-6781284.
STRING9606.ENSP00000223324.

PTM databases

PhosphoSiteQ9BYC8.

Polymorphism databases

DMDM22001923.

Proteomic databases

MaxQBQ9BYC8.
PaxDbQ9BYC8.
PRIDEQ9BYC8.

Protocols and materials databases

DNASU64983.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000223324; ENSP00000223324; ENSG00000106591.
GeneID64983.
KEGGhsa:64983.
UCSCuc003tia.3. human.

Organism-specific databases

CTD64983.
GeneCardsGC07P042971.
HGNCHGNC:14035. MRPL32.
HPAHPA048965.
MIM611839. gene.
neXtProtNX_Q9BYC8.
PharmGKBPA30963.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG297873.
HOGENOMHOG000252980.
HOVERGENHBG036112.
InParanoidQ9BYC8.
KOK02911.
OMAVPPWPAA.
OrthoDBEOG7C2R2G.
PhylomeDBQ9BYC8.
TreeFamTF106139.

Gene expression databases

ArrayExpressQ9BYC8.
BgeeQ9BYC8.
CleanExHS_MRPL32.
GenevestigatorQ9BYC8.

Family and domain databases

InterProIPR002677. Ribosomal_L32p.
IPR011332. Ribosomal_zn-bd.
[Graphical view]
PfamPF01783. Ribosomal_L32p. 1 hit.
[Graphical view]
SUPFAMSSF57829. SSF57829. 1 hit.
ProtoNetSearch...

Other

GeneWikiMRPL32.
GenomeRNAi64983.
NextBio67176.
PROQ9BYC8.
SOURCESearch...

Entry information

Entry nameRM32_HUMAN
AccessionPrimary (citable) accession number: Q9BYC8
Secondary accession number(s): Q96Q68, Q9P098
Entry history
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 7

Human chromosome 7: entries, gene names and cross-references to MIM