##gff-version 3
Q9BY50	UniProtKB	Chain	1	192	.	.	.	ID=PRO_0000109548;Note=Signal peptidase complex catalytic subunit SEC11C	
Q9BY50	UniProtKB	Topological domain	1	28	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P13679	
Q9BY50	UniProtKB	Transmembrane	29	48	.	.	.	Note=Helical%3B Signal-anchor for type II membrane protein;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q9BY50	UniProtKB	Topological domain	49	192	.	.	.	Note=Lumenal;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P13679	
Q9BY50	UniProtKB	Region	177	188	.	.	.	Note=C-terminal short (CTS) helix;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Active site	68	68	.	.	.	Note=Charge relay system;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Active site	108	108	.	.	.	Note=Charge relay system;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Active site	134	134	.	.	.	Note=Charge relay system;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	68	68	.	.	.	Note=Loss of catalytic activity. S->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	109	109	.	.	.	Note=Slight reduction in catalytic activity%3B when associated with R-128. R->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	128	128	.	.	.	Note=Moderate reduction in catalytic activity. Reduces protein stability. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	128	128	.	.	.	Note=Slight reduction in catalytic activity%3B when associated with D-109. D->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	133	133	.	.	.	Note=No effect on catalytic activity or protein stability. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369	
Q9BY50	UniProtKB	Mutagenesis	134	134	.	.	.	Note=Loss of catalytic activity. Slight reduction in protein stability. D->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:34388369;Dbxref=PMID:34388369