Q9BXU1 (STK31_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine/threonine-protein kinase 31
EC=2.7.11.1

Alternative name(s):
Serine/threonine-protein kinase NYD-SPK
Sugen kinase 396
Short name=SgK396

Gene names

Name:	STK31
Synonyms:	SGK396

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1019 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a protein = ADP + a phosphoprotein.
Tissue specificity	Testis specific.
Sequence similarities	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Contains 1 protein kinase domain. Contains 1 Tudor domain.
Caution	Ser-854 is present instead of the conserved Asp which is expected to be an active site residue.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Coiled coil
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein serine/threonine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9BXU1-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9BXU1-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-23: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q9BXU1-3)

The sequence of this isoform differs from the canonical sequence as follows:
     921-943: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1019	1019	Serine/threonine-protein kinase 31		PRO_0000086715
Regions
	Domain	78 – 137	60	Tudor
	Domain	710 – 1019	310	Protein kinase
	Nucleotide binding	716 – 724	9	ATP By similarity
	Coiled coil	298 – 355	58	Potential
Sites
	Binding site	737	1	ATP By similarity
Natural variations
	Alternative sequence	1 – 23	23	Missing in isoform 2.		VSP_024389
	Alternative sequence	921 – 943	23	Missing in isoform 3.		VSP_045210
	Natural variant	71	1	Q → H. Ref.5 Ref.6 Corresponds to variant rs6945306 [ dbSNP | Ensembl ].		VAR_031600
	Natural variant	125	1	S → F. Ref.6 Corresponds to variant rs56268851 [ dbSNP | Ensembl ].		VAR_041150
	Natural variant	261	1	E → K. Ref.6 Corresponds to variant rs10264952 [ dbSNP | Ensembl ].		VAR_031601
	Natural variant	268	1	K → N. Ref.6 Corresponds to variant rs10264967 [ dbSNP | Ensembl ].		VAR_031602
	Natural variant	277	1	I → K. Ref.6 Corresponds to variant rs55950645 [ dbSNP | Ensembl ].		VAR_041151
	Natural variant	362	1	T → P. Corresponds to variant rs35545265 [ dbSNP | Ensembl ].		VAR_031603
	Natural variant	385	1	R → C. Corresponds to variant rs35995607 [ dbSNP | Ensembl ].		VAR_051675
	Natural variant	393	1	A → T. Ref.6 Corresponds to variant rs56244148 [ dbSNP | Ensembl ].		VAR_041152
	Natural variant	410	1	G → E. Ref.6 Corresponds to variant rs4722266 [ dbSNP | Ensembl ].		VAR_031604
	Natural variant	489	1	A → P. Ref.6 Corresponds to variant rs34414354 [ dbSNP | Ensembl ].		VAR_041153
	Natural variant	600	1	A → T. Ref.6 Corresponds to variant rs55796076 [ dbSNP | Ensembl ].		VAR_041154
	Natural variant	621	1	N → K. Ref.6 Corresponds to variant rs10263079 [ dbSNP | Ensembl ].		VAR_041155
	Natural variant	623	1	S → I. Ref.6 Corresponds to variant rs10247878 [ dbSNP | Ensembl ].		VAR_041156
	Natural variant	684	1	H → R. Ref.6 Corresponds to variant rs41273999 [ dbSNP | Ensembl ].		VAR_041157
	Natural variant	684	1	H → Y in a lung neuroendocrine carcinoma sample; somatic mutation. Ref.6		VAR_041158
	Natural variant	709	1	E → K. Ref.6 Corresponds to variant rs56181834 [ dbSNP | Ensembl ].		VAR_041159
	Natural variant	860	1	V → L in a lung small cell carcinoma sample; somatic mutation. Ref.6		VAR_041160
	Natural variant	1000	1	T → M. Ref.6 Corresponds to variant rs55794023 [ dbSNP | Ensembl ].		VAR_041161
	Natural variant	1009	1	K → T. Corresponds to variant rs33998018 [ dbSNP | Ensembl ].		VAR_031605
	Natural variant	1010	1	T → S. Ref.6 Corresponds to variant rs56391043 [ dbSNP | Ensembl ].		VAR_041162
Experimental info
	Sequence conflict	300	1	I → F in AAK17193. Ref.2
	Sequence conflict	509	1	F → Y in AAK17193. Ref.2
	Sequence conflict	621 – 623	3	NKS → KKI in AAK31978. Ref.1
	Sequence conflict	715	1	Y → C in AAK17193. Ref.2
	Sequence conflict	820	1	V → A in AAK17193. Ref.2
	Sequence conflict	948	1	K → I in AAK17193. Ref.2
	Sequence conflict	963	1	A → G in AAK17193. Ref.2
	Sequence conflict	1000	1	T → P in AAK17193. Ref.2
	Sequence conflict	1010	1	T → P in AAK31978. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified April 3, 2007. Version 2. Checksum: C2EFF005A820E102	FASTA	1,019	115,694
	10 20 30 40 50 60 MWVQGHSSRA SATESVSFSG IVQMDEDTHY DKVEDVVGSH IEDAVTFWAQ SINRNKDIMK 70 80 90 100 110 120 IGCSLSEVCP QASSVLGNLD PNKIYGGLFS EDQCWYRCKV LKIISVEKCL VRYIDYGNTE 130 140 150 160 170 180 ILNRSDIVEI PLELQFSSVA KKYKLWGLHI PSDQEVTQFD QGTTFLGSLI FEKEIKMRIK 190 200 210 220 230 240 ATSEDGTVIA QAEYGSVDIG EEVLKKGFAE KCRLASRTDI CEEKKLDPGQ LVLRNLKSPI 250 260 270 280 290 300 PLWGHRSNQS TFSRPKGHLS EKMTLDLKDE NDAGNLITFP KESLAVGDFN LGSNVSLEKI 310 320 330 340 350 360 KQDQKLIEEN EKLKTEKDAL LESYKALELK VEQIAQELQQ EKAAAVDLTN HLEYTLKTYI 370 380 390 400 410 420 DTRMKNLAAK MEILKEMRHV DISVRFGKDL SDAIQVLDEG CFTTPASLNG LEIIWAEYSL 430 440 450 460 470 480 AQENIKTCEY VSEGNILIAQ RNEMQQKLYM SVEDFILEVD ESSLNKRLKT LQDLSVSLEA 490 500 510 520 530 540 VYGQAKEGAN SDEILKKFYD WKCDKREEFT SVRSETDASL HRLVAWFQRT LKVFDLSVEG 550 560 570 580 590 600 SLISEDAMDN IDEILEKTES SVCKELEIAL VDQGDADKEI ISNTYSQVLQ KIHSEERLIA 610 620 630 640 650 660 TVQAKYKDSI EFKKQLIEYL NKSPSVDHLL SIKKTLKSLK ALLRWKLVEK SNLEESDDPD 670 680 690 700 710 720 GSQIEKIKEE ITQLRNNVFQ EIYHEREEYE MLTSLAQKWF PELPLLHPEI GLLKYMNSGG 730 740 750 760 770 780 LLTMSLERDL LDAEPMKELS SKRPLVRSEV NGQIILLKGY SVDVDTEAKV IERAATYHRA 790 800 810 820 830 840 WREAEGDSGL LPLIFLFLCK SDPMAYLMVP YYPRANLNAV QANMPLNSEE TLKVMKGVAQ 850 860 870 880 890 900 GLHTLHKADI IHGSLHQNNV FALNREQGIV GDFDFTKSVS QRASVNMMVG DLSLMSPELK 910 920 930 940 950 960 MGKPASPGSD LYAYGCLLLW LSVQNQEFEI NKDGIPKVDQ FHLDDKVKSL LCSLICYRSS 970 980 990 1000 1010 MTAEQVLNAE CFLMPKEQSV PNPEKDTEYT LYKKEEEIKT ENLDKCMEKT RNGEANFDC
	Isoform 2 [UniParc]. Checksum: E9D528F7DE7D2CDC	FASTA	996	113,260
	10 20 30 40 50 60 MDEDTHYDKV EDVVGSHIED AVTFWAQSIN RNKDIMKIGC SLSEVCPQAS SVLGNLDPNK 70 80 90 100 110 120 IYGGLFSEDQ CWYRCKVLKI ISVEKCLVRY IDYGNTEILN RSDIVEIPLE LQFSSVAKKY 130 140 150 160 170 180 KLWGLHIPSD QEVTQFDQGT TFLGSLIFEK EIKMRIKATS EDGTVIAQAE YGSVDIGEEV 190 200 210 220 230 240 LKKGFAEKCR LASRTDICEE KKLDPGQLVL RNLKSPIPLW GHRSNQSTFS RPKGHLSEKM 250 260 270 280 290 300 TLDLKDENDA GNLITFPKES LAVGDFNLGS NVSLEKIKQD QKLIEENEKL KTEKDALLES 310 320 330 340 350 360 YKALELKVEQ IAQELQQEKA AAVDLTNHLE YTLKTYIDTR MKNLAAKMEI LKEMRHVDIS 370 380 390 400 410 420 VRFGKDLSDA IQVLDEGCFT TPASLNGLEI IWAEYSLAQE NIKTCEYVSE GNILIAQRNE 430 440 450 460 470 480 MQQKLYMSVE DFILEVDESS LNKRLKTLQD LSVSLEAVYG QAKEGANSDE ILKKFYDWKC 490 500 510 520 530 540 DKREEFTSVR SETDASLHRL VAWFQRTLKV FDLSVEGSLI SEDAMDNIDE ILEKTESSVC 550 560 570 580 590 600 KELEIALVDQ GDADKEIISN TYSQVLQKIH SEERLIATVQ AKYKDSIEFK KQLIEYLNKS 610 620 630 640 650 660 PSVDHLLSIK KTLKSLKALL RWKLVEKSNL EESDDPDGSQ IEKIKEEITQ LRNNVFQEIY 670 680 690 700 710 720 HEREEYEMLT SLAQKWFPEL PLLHPEIGLL KYMNSGGLLT MSLERDLLDA EPMKELSSKR 730 740 750 760 770 780 PLVRSEVNGQ IILLKGYSVD VDTEAKVIER AATYHRAWRE AEGDSGLLPL IFLFLCKSDP 790 800 810 820 830 840 MAYLMVPYYP RANLNAVQAN MPLNSEETLK VMKGVAQGLH TLHKADIIHG SLHQNNVFAL 850 860 870 880 890 900 NREQGIVGDF DFTKSVSQRA SVNMMVGDLS LMSPELKMGK PASPGSDLYA YGCLLLWLSV 910 920 930 940 950 960 QNQEFEINKD GIPKVDQFHL DDKVKSLLCS LICYRSSMTA EQVLNAECFL MPKEQSVPNP 970 980 990 EKDTEYTLYK KEEEIKTENL DKCMEKTRNG EANFDC
	Isoform 3 [UniParc]. Checksum: 753B3B79DBF556E8	FASTA	996	113,013
	10 20 30 40 50 60 MWVQGHSSRA SATESVSFSG IVQMDEDTHY DKVEDVVGSH IEDAVTFWAQ SINRNKDIMK 70 80 90 100 110 120 IGCSLSEVCP QASSVLGNLD PNKIYGGLFS EDQCWYRCKV LKIISVEKCL VRYIDYGNTE 130 140 150 160 170 180 ILNRSDIVEI PLELQFSSVA KKYKLWGLHI PSDQEVTQFD QGTTFLGSLI FEKEIKMRIK 190 200 210 220 230 240 ATSEDGTVIA QAEYGSVDIG EEVLKKGFAE KCRLASRTDI CEEKKLDPGQ LVLRNLKSPI 250 260 270 280 290 300 PLWGHRSNQS TFSRPKGHLS EKMTLDLKDE NDAGNLITFP KESLAVGDFN LGSNVSLEKI 310 320 330 340 350 360 KQDQKLIEEN EKLKTEKDAL LESYKALELK VEQIAQELQQ EKAAAVDLTN HLEYTLKTYI 370 380 390 400 410 420 DTRMKNLAAK MEILKEMRHV DISVRFGKDL SDAIQVLDEG CFTTPASLNG LEIIWAEYSL 430 440 450 460 470 480 AQENIKTCEY VSEGNILIAQ RNEMQQKLYM SVEDFILEVD ESSLNKRLKT LQDLSVSLEA 490 500 510 520 530 540 VYGQAKEGAN SDEILKKFYD WKCDKREEFT SVRSETDASL HRLVAWFQRT LKVFDLSVEG 550 560 570 580 590 600 SLISEDAMDN IDEILEKTES SVCKELEIAL VDQGDADKEI ISNTYSQVLQ KIHSEERLIA 610 620 630 640 650 660 TVQAKYKDSI EFKKQLIEYL NKSPSVDHLL SIKKTLKSLK ALLRWKLVEK SNLEESDDPD 670 680 690 700 710 720 GSQIEKIKEE ITQLRNNVFQ EIYHEREEYE MLTSLAQKWF PELPLLHPEI GLLKYMNSGG 730 740 750 760 770 780 LLTMSLERDL LDAEPMKELS SKRPLVRSEV NGQIILLKGY SVDVDTEAKV IERAATYHRA 790 800 810 820 830 840 WREAEGDSGL LPLIFLFLCK SDPMAYLMVP YYPRANLNAV QANMPLNSEE TLKVMKGVAQ 850 860 870 880 890 900 GLHTLHKADI IHGSLHQNNV FALNREQGIV GDFDFTKSVS QRASVNMMVG DLSLMSPELK 910 920 930 940 950 960 MGKPASPGSD LYAYGCLLLW DDKVKSLLCS LICYRSSMTA EQVLNAECFL MPKEQSVPNP 970 980 990 EKDTEYTLYK KEEEIKTENL DKCMEKTRNG EANFDC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"An abundance of X-linked genes expressed in spermatogonia." Wang P.J., McCarrey J.R., Yang F., Page D.C. Nat. Genet. 27:422-426(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Testis.
[2]	"Cloning of a new protein kinase gene related to human testis development." Zhou Z.M. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Testis.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Testis.
[4]	"The DNA sequence of human chromosome 7." Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H., Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A., Delehaunty K.D., Miner T.L. , Nash W.E., Cordes M., Du H., Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C., Latreille P., Miller N., Johnson D., Murray J., Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E., Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H., Wilson R.K. Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT HIS-71. Tissue: Testis.
[6]	"Patterns of somatic mutation in human cancer genomes." Greenman C., Stephens P., Smith R., Dalgliesh G.L., Hunter C., Bignell G., Davies H., Teague J., Butler A., Stevens C., Edkins S., O'Meara S., Vastrik I., Schmidt E.E., Avis T., Barthorpe S., Bhamra G., Buck G. , Choudhury B., Clements J., Cole J., Dicks E., Forbes S., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jenkinson A., Jones D., Menzies A., Mironenko T., Perry J., Raine K., Richardson D., Shepherd R., Small A., Tofts C., Varian J., Webb T., West S., Widaa S., Yates A., Cahill D.P., Louis D.N., Goldstraw P., Nicholson A.G., Brasseur F., Looijenga L., Weber B.L., Chiew Y.-E., DeFazio A., Greaves M.F., Green A.R., Campbell P., Birney E., Easton D.F., Chenevix-Trench G., Tan M.-H., Khoo S.K., Teh B.T., Yuen S.T., Leung S.Y., Wooster R., Futreal P.A., Stratton M.R. Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANTS [LARGE SCALE ANALYSIS] HIS-71; PHE-125; LYS-261; ASN-268; LYS-277; THR-393; GLU-410; PRO-489; THR-600; LYS-621; ILE-623; ARG-684; TYR-684; LYS-709; LEU-860; MET-1000 AND SER-1010.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF285599 mRNA. Translation: AAK31978.1. AF332194 mRNA. Translation: AAK17193.1. AK302689 mRNA. Translation: BAG63918.1. AC003087 Genomic DNA. No translation available. AC008176 Genomic DNA. No translation available. BC059374 mRNA. Translation: AAH59374.1.
IPI	IPI00419204. IPI00843776.
RefSeq	NP_001247433.1. NM_001260504.1. NP_001247434.1. NM_001260505.1. NP_113602.2. NM_031414.4. NP_116562.2. NM_032944.3.
UniGene	Hs.309767.
3D structure databases
ProteinModelPortal	Q9BXU1.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BXU1. 1 interaction.
STRING	9606.ENSP00000348132.
PTM databases
PhosphoSite	Q9BXU1.
Polymorphism databases
DMDM	143811463.
Proteomic databases
PaxDb	Q9BXU1.
PRIDE	Q9BXU1.
Protocols and materials databases
DNASU	56164.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000354639; ENSP00000346660; ENSG00000196335. ENST00000355870; ENSP00000348132; ENSG00000196335. ENST00000428484; ENSP00000406146; ENSG00000196335. ENST00000433467; ENSP00000411852; ENSG00000196335.
GeneID	56164.
KEGG	hsa:56164.
UCSC	uc003sws.4. human.
Organism-specific databases
CTD	56164.
GeneCards	GC07P023749.
H-InvDB	HIX0006524.
HGNC	HGNC:11407. STK31.
HPA	HPA023194.
MIM	605790. gene.
neXtProt	NX_Q9BXU1.
PharmGKB	PA36214.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG81566.
HOGENOM	HOG000154440.
HOVERGEN	HBG062739.
InParanoid	Q9BXU1.
KO	K16316.
OMA	IPKVDQF.
OrthoDB	EOG4GHZND.
Gene expression databases
ArrayExpress	Q9BXU1.
Bgee	Q9BXU1.
CleanEx	HS_STK31.
Genevestigator	Q9BXU1.
GermOnline	ENSG00000196335. Homo sapiens.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR002999. Tudor. [Graphical view]
Pfam	PF00069. Pkinase. 1 hit. PF00567. TUDOR. 1 hit. [Graphical view]
SMART	SM00333. TUDOR. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. False negative. PS50304. TUDOR. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	Q9BXU1.
ChEMBL	CHEMBL6151.
GenomeRNAi	56164.
NextBio	61796.
SOURCE	Search...

Entry information

Entry name

STK31_HUMAN

Accession

Primary (citable) accession number: Q9BXU1
Secondary accession number(s): B4DZ06 , B7WPP5, C9J4F9, Q6PCD3, Q9BXH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	April 3, 2007
Last modified:	May 1, 2013
This is version 112 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.