Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9BXK5

- B2L13_HUMAN

UniProt

Q9BXK5 - B2L13_HUMAN

Protein

Bcl-2-like protein 13

Gene

BCL2L13

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 131 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    May promote the activation of caspase-3 and apoptosis.

    GO - Molecular functioni

    1. cysteine-type endopeptidase activator activity involved in apoptotic process Source: UniProtKB

    GO - Biological processi

    1. activation of cysteine-type endopeptidase activity involved in apoptotic process Source: UniProtKB
    2. apoptotic process Source: UniProtKB

    Keywords - Biological processi

    Apoptosis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Bcl-2-like protein 13
    Short name:
    Bcl2-L-13
    Alternative name(s):
    Bcl-rambo
    Protein Mil1
    Gene namesi
    Name:BCL2L13
    Synonyms:MIL1
    ORF Names:CD003
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 22

    Organism-specific databases

    HGNCiHGNC:17164. BCL2L13.

    Subcellular locationi

    Isoform 1 : Nucleus Curated

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB
    2. mitochondrial membrane Source: UniProtKB-SubCell
    3. mitochondrion Source: UniProtKB
    4. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134912159.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 485485Bcl-2-like protein 13PRO_0000143073Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei38 – 381Phosphoserine1 Publication
    Modified residuei371 – 3711PhosphoserineBy similarity
    Modified residuei420 – 4201Phosphoserine3 Publications
    Modified residuei426 – 4261Phosphoserine3 Publications
    Modified residuei429 – 4291Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ9BXK5.
    PaxDbiQ9BXK5.
    PeptideAtlasiQ9BXK5.
    PRIDEiQ9BXK5.

    PTM databases

    PhosphoSiteiQ9BXK5.

    Expressioni

    Tissue specificityi

    Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.

    Gene expression databases

    ArrayExpressiQ9BXK5.
    BgeeiQ9BXK5.
    CleanExiHS_BCL2L13.
    GenevestigatoriQ9BXK5.

    Organism-specific databases

    HPAiCAB002052.
    HPA030994.
    HPA050377.

    Interactioni

    Subunit structurei

    Monomer.Curated

    Protein-protein interaction databases

    BioGridi117285. 3 interactions.
    DIPiDIP-60895N.
    IntActiQ9BXK5. 8 interactions.
    MINTiMINT-4538648.
    STRINGi9606.ENSP00000318883.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2IPDmodel-@1-485[»]
    ProteinModelPortaliQ9BXK5.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei460 – 48021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati246 – 25611AAdd
    BLAST
    Repeati261 – 27111A; approximateAdd
    BLAST
    Repeati425 – 44117BAdd
    BLAST
    Repeati443 – 45917B; approximateAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi14 – 3017BH4Add
    BLAST
    Motifi100 – 11617BH3Add
    BLAST
    Motifi147 – 15711BH1Add
    BLAST
    Motifi193 – 20614BH2Add
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi207 – 2126Poly-Glu
    Compositional biasi311 – 424114Glu-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the Bcl-2 family.Curated

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG44929.
    HOGENOMiHOG000059276.
    HOVERGENiHBG050648.
    InParanoidiQ9BXK5.
    KOiK15485.
    OMAiSQPVTYQ.
    OrthoDBiEOG77M8PW.
    PhylomeDBiQ9BXK5.
    TreeFamiTF330744.

    Family and domain databases

    InterProiIPR002475. Bcl2-like.
    IPR026298. Blc2_fam.
    [Graphical view]
    PfamiPF00452. Bcl-2. 1 hit.
    [Graphical view]
    PROSITEiPS50062. BCL2_FAMILY. 1 hit.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Note: Experimental confirmation may be lacking for some isoforms.

    Isoform 2 (identifier: Q9BXK5-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MASSSTVPLG FHYETKYVVL SYLGLLSQEK LQEQHLSSPQ GVQLDIASQS    50
    LDQEILLKVK TEIEEELKSL DKEISEAFTS TGFDRHTSPV FSPANPESSM 100
    EDCLAHLGEK VSQELKEPLH KALQMLLSQP VTYQAFRECT LETTVHASGW 150
    NKILVPLVLL RQMLLELTRR GQEPLSALLQ FGVTYLEDYS AEYIIQQGGW 200
    GTVFSLESEE EEYPGITAED SNDIYILPSD NSGQVSPPES PTVTTSWQSE 250
    SLPVSLSASQ SWHTESLPVS LGPESWQQIA MDPEEVKSLD SNGAGEKSEN 300
    NSSNSDIVHV EKEEVPEGME EAAVASVVLP ARELQEALPE APAPLLPHIT 350
    ATSLLGTREP DTEVITVEKS SPATSLFVEL DEEEVKAATT EPTEVEEVVP 400
    ALEPTETLLS EKEINAREES LVEELSPASE KKPVPPSEGK SRLSPAGEMK 450
    PMPLSEGKSI LLFGGAAAVA ILAVAIGVAL ALRKK 485
    Length:485
    Mass (Da):52,723
    Last modified:June 1, 2001 - v1
    Checksum:iD9404665111B6CE0
    GO
    Isoform 1 (identifier: Q9BXK5-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         201-201: G → V
         202-485: Missing.

    Show »
    Length:201
    Mass (Da):22,612
    Checksum:iC343D4873BCC2A91
    GO
    Isoform 3 (identifier: Q9BXK5-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-162: Missing.

    Show »
    Length:323
    Mass (Da):34,601
    Checksum:i77A9CADD907ED1F9
    GO

    Sequence cautioni

    The sequence AAG09680.1 differs from that shown. Reason: Frameshift at several positions.
    The sequence AAF03602.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti170 – 1701R → L in AAF03602. 1 PublicationCurated
    Sequence conflicti391 – 3911E → Q in CAB61361. (PubMed:17974005)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti46 – 461I → R.1 Publication
    Corresponds to variant rs2587070 [ dbSNP | Ensembl ].
    VAR_059141
    Natural varianti46 – 461I → T.
    Corresponds to variant rs2587070 [ dbSNP | Ensembl ].
    VAR_059142
    Natural varianti55 – 551I → V.
    Corresponds to variant rs16981016 [ dbSNP | Ensembl ].
    VAR_024377
    Natural varianti360 – 3601P → S.1 Publication
    Corresponds to variant rs9306198 [ dbSNP | Ensembl ].
    VAR_024378

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 162162Missing in isoform 3. 1 PublicationVSP_046931Add
    BLAST
    Alternative sequencei201 – 2011G → V in isoform 1. 3 PublicationsVSP_000526
    Alternative sequencei202 – 485284Missing in isoform 1. 3 PublicationsVSP_000527Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF325209 mRNA. Translation: AAK27358.1.
    AF246665 mRNA. Translation: AAK15150.1.
    AF183411 mRNA. Translation: AAG09680.1. Frameshift.
    CR456521 mRNA. Translation: CAG30407.1.
    AK056248 mRNA. Translation: BAG51659.1.
    AC006285 Genomic DNA. No translation available.
    BC007658 mRNA. Translation: AAH07658.1.
    BC016037 mRNA. Translation: AAH16037.1.
    AF146568 mRNA. Translation: AAF03602.1. Different initiation.
    AL133029 mRNA. Translation: CAB61361.1.
    CCDSiCCDS13746.1. [Q9BXK5-1]
    CCDS59448.1. [Q9BXK5-4]
    PIRiT42703.
    RefSeqiNP_001257658.1. NM_001270729.1. [Q9BXK5-4]
    NP_001257659.1. NM_001270730.1. [Q9BXK5-4]
    NP_001257660.1. NM_001270731.1. [Q9BXK5-4]
    NP_056182.2. NM_015367.3. [Q9BXK5-1]
    XP_006724139.1. XM_006724076.1. [Q9BXK5-4]
    UniGeneiHs.631672.

    Genome annotation databases

    EnsembliENST00000317582; ENSP00000318883; ENSG00000099968. [Q9BXK5-1]
    ENST00000337612; ENSP00000338932; ENSG00000099968. [Q9BXK5-4]
    ENST00000399782; ENSP00000382682; ENSG00000099968. [Q9BXK5-2]
    ENST00000493680; ENSP00000434764; ENSG00000099968. [Q9BXK5-2]
    ENST00000543133; ENSP00000437667; ENSG00000099968. [Q9BXK5-4]
    GeneIDi23786.
    KEGGihsa:23786.
    UCSCiuc002zmu.3. human. [Q9BXK5-2]
    uc002zmw.4. human. [Q9BXK5-1]

    Polymorphism databases

    DMDMi23396740.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF325209 mRNA. Translation: AAK27358.1 .
    AF246665 mRNA. Translation: AAK15150.1 .
    AF183411 mRNA. Translation: AAG09680.1 . Frameshift.
    CR456521 mRNA. Translation: CAG30407.1 .
    AK056248 mRNA. Translation: BAG51659.1 .
    AC006285 Genomic DNA. No translation available.
    BC007658 mRNA. Translation: AAH07658.1 .
    BC016037 mRNA. Translation: AAH16037.1 .
    AF146568 mRNA. Translation: AAF03602.1 . Different initiation.
    AL133029 mRNA. Translation: CAB61361.1 .
    CCDSi CCDS13746.1. [Q9BXK5-1 ]
    CCDS59448.1. [Q9BXK5-4 ]
    PIRi T42703.
    RefSeqi NP_001257658.1. NM_001270729.1. [Q9BXK5-4 ]
    NP_001257659.1. NM_001270730.1. [Q9BXK5-4 ]
    NP_001257660.1. NM_001270731.1. [Q9BXK5-4 ]
    NP_056182.2. NM_015367.3. [Q9BXK5-1 ]
    XP_006724139.1. XM_006724076.1. [Q9BXK5-4 ]
    UniGenei Hs.631672.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2IPD model - @ 1-485 [» ]
    ProteinModelPortali Q9BXK5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 117285. 3 interactions.
    DIPi DIP-60895N.
    IntActi Q9BXK5. 8 interactions.
    MINTi MINT-4538648.
    STRINGi 9606.ENSP00000318883.

    PTM databases

    PhosphoSitei Q9BXK5.

    Polymorphism databases

    DMDMi 23396740.

    Proteomic databases

    MaxQBi Q9BXK5.
    PaxDbi Q9BXK5.
    PeptideAtlasi Q9BXK5.
    PRIDEi Q9BXK5.

    Protocols and materials databases

    DNASUi 23786.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000317582 ; ENSP00000318883 ; ENSG00000099968 . [Q9BXK5-1 ]
    ENST00000337612 ; ENSP00000338932 ; ENSG00000099968 . [Q9BXK5-4 ]
    ENST00000399782 ; ENSP00000382682 ; ENSG00000099968 . [Q9BXK5-2 ]
    ENST00000493680 ; ENSP00000434764 ; ENSG00000099968 . [Q9BXK5-2 ]
    ENST00000543133 ; ENSP00000437667 ; ENSG00000099968 . [Q9BXK5-4 ]
    GeneIDi 23786.
    KEGGi hsa:23786.
    UCSCi uc002zmu.3. human. [Q9BXK5-2 ]
    uc002zmw.4. human. [Q9BXK5-1 ]

    Organism-specific databases

    CTDi 23786.
    GeneCardsi GC22P018111.
    HGNCi HGNC:17164. BCL2L13.
    HPAi CAB002052.
    HPA030994.
    HPA050377.
    neXtProti NX_Q9BXK5.
    PharmGKBi PA134912159.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG44929.
    HOGENOMi HOG000059276.
    HOVERGENi HBG050648.
    InParanoidi Q9BXK5.
    KOi K15485.
    OMAi SQPVTYQ.
    OrthoDBi EOG77M8PW.
    PhylomeDBi Q9BXK5.
    TreeFami TF330744.

    Miscellaneous databases

    GeneWikii BCL2L13.
    GenomeRNAii 23786.
    NextBioi 35469201.
    PROi Q9BXK5.

    Gene expression databases

    ArrayExpressi Q9BXK5.
    Bgeei Q9BXK5.
    CleanExi HS_BCL2L13.
    Genevestigatori Q9BXK5.

    Family and domain databases

    InterProi IPR002475. Bcl2-like.
    IPR026298. Blc2_fam.
    [Graphical view ]
    Pfami PF00452. Bcl-2. 1 hit.
    [Graphical view ]
    PROSITEi PS50062. BCL2_FAMILY. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension."
      Kataoka T., Holler N., Micheau O., Martinon F., Tinel A., Hofmann K., Tschopp J.
      J. Biol. Chem. 276:19548-19554(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    2. "Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere."
      Footz T.K., Brinkman-Mills P., Banting G.S., Maier S.A., Riazi M.A., Bridgland L.J., Hu S., Birren B., Minoshima S., Shimizu N., Pan H., Nguyen T., Fang F., Fu Y., Ray L., Wu H., Shaull S., Phan S.
      , Yao Z., Chen F., Huan A., Hu P., Wang Q., Loh P., Qi S., Roe B.A., McDermid H.E.
      Genome Res. 11:1053-1070(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    3. "A novel gene expressed in human pheochromocytoma."
      Li Y., Peng Y., Li N., Gu W., Han Z., Fu G., Chen Z.
      Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Pheochromocytoma.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
      Tissue: Teratocarcinoma.
    6. "The DNA sequence of human chromosome 22."
      Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M.
      , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H.
      Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT SER-360.
      Tissue: Eye and Skin.
    8. "Mil1, a novel human gene encoding mitochondria located protein promoting cell survival."
      Zemskova M.Y., Lilly M., Escher A.P.
      Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 77-485 (ISOFORM 2).
      Tissue: Glial tumor.
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 183-485 (ISOFORM 2).
      Tissue: Testis.
    10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-38; SER-420 AND SER-426, VARIANT [LARGE SCALE ANALYSIS] ARG-46, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420; SER-426 AND SER-429, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-420 AND SER-426, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiB2L13_HUMAN
    AccessioniPrimary (citable) accession number: Q9BXK5
    Secondary accession number(s): B3KPE7
    , Q96B37, Q96IB7, Q9BY01, Q9HC05, Q9UFE0, Q9UKN3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 19, 2002
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 131 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 22
      Human chromosome 22: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3