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Reviewed, UniProtKB/Swiss-Prot Q9BXJ5 (C1QT2_HUMAN)

Last modified January 19, 2010. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Complement C1q tumor necrosis factor-related protein 2
Gene names
Name: C1QTNF2
Synonyms: CTRP2
ORF Names: UNQ6349/PRO21054
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length285 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Subcellular location

Secreted Potential.

Sequence similarities

Contains 1 C1q domain.

Contains 1 collagen-like domain.

Ontologies

Keywords
   Cellular componentSecreted
   DomainCollagen
Signal
   Technical termComplete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1515 Potential
Chain16 – 285270Complement C1q tumor necrosis factor-related protein 2
PRO_0000003530

Regions

Domain40 – 141102Collagen-like
Domain145 – 285141C1q

Sequences

Sequence LengthMass (Da)Tools
Q9BXJ5-1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 7E31FF9868D4EDFA

FASTA28529,952
        10         20         30         40         50         60 
MIPWVLLACA LPCAADPLLG AFARRDFRKG SPQLVCSLPG PQGPPGPPGA PGPSGMMGRM 

        70         80         90        100        110        120 
GFPGKDGQDG HDGDRGDSGE EGPPGRTGNR GKPGPKGKAG AIGRAGPRGP KGVNGTPGKH 

       130        140        150        160        170        180 
GTPGKKGPKG KKGEPGLPGP CSCGSGHTKS AFSVAVTKSY PRERLPIKFD KILMNEGGHY 

       190        200        210        220        230        240 
NASSGKFVCG VPGIYYFTYD ITLANKHLAI GLVHNGQYRI RTFDANTGNH DVASGSTILA 

       250        260        270        280 
LKQGDEVWLQ IFYSEQNGLF YDPYWTDSLF TGFLIYADQD DPNEV 

« Hide

References

« Hide 'large scale' references
[1]"Homo sapiens complement-c1q tumor necrosis factor-related protein."
Piddington C.S., Bishop P.
Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed: 12975309] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. expand/collapse author list , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
Nature 431:268-274(2004) [PubMed: 15372022] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain and Muscle.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF329836 mRNA. Translation: AAK17960.1.
AY358839 mRNA. Translation: AAQ89198.1.
AC091842 Genomic DNA. No translation available.
AC112191 Genomic DNA. No translation available.
BC011699 mRNA. Translation: AAH11699.2. Different initiation.
BC054506 mRNA. Translation: AAH54506.2. Different initiation.
IPIIPI00011093.
RefSeqNP_114114.2.
UniGeneHs.110062

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9BXJ5.

Proteomic databases

PRIDEQ9BXJ5.

Genome annotation databases

EnsemblENST00000393975; ENSP00000377545; ENSG00000145861; Homo sapiens. [Genome view]
GeneID114898.
KEGGhsa:114898.
UCSCuc003lyd.1. human.

Organism-specific databases

CTD114898.
GeneCardsGC05M159707.
H-InvDBHIX0005376.
HGNCHGNC:14325. C1QTNF2.
PharmGKBPA25629.
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG12474.
HOGENOMHBG444750.
HOVERGENQ9BXJ5.
InParanoidQ9BXJ5.
PhylomeDBQ9BXJ5.

Gene expression databases

ArrayExpressQ9BXJ5.
BgeeQ9BXJ5.
CleanExHS_C1QTNF2.
GenevestigatorQ9BXJ5.
GermOnlineENSG00000145861. Homo sapiens.

Family and domain databases

InterProIPR001073. C1q.
IPR008160. Collagen.
IPR008983. Tumour_necrosis_fac-like.
[Graphical view]
Gene3DG3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
PfamPF00386. C1q. 1 hit.
PF01391. Collagen. 2 hits.
[Graphical view]
PRINTSPR00007. COMPLEMNTC1Q.
SMARTSM00110. C1Q. 1 hit.
[Graphical view]
PROSITEPS50871. C1Q. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio79402.

Entry information

Entry nameC1QT2_HUMAN
AccessionPrimary (citable) accession number: Q9BXJ5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: June 1, 2001
Last modified: January 19, 2010
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 5

Human chromosome 5: entries, gene names and cross-references to MIM

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents