Reviewed, UniProtKB/Swiss-Prot Q9BXJ2 (C1QT7_HUMAN)

Names and origin

Protein names

Recommended name:
    Complement C1q tumor necrosis factor-related protein 7

Gene names

Name:	C1QTNF7
Synonyms:	CTRP7

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	SecretedPotential.
Sequence similarities	Contains 1 C1q domain. Contains 1 collagen-like domain.

Ontologies

Keywords
Cellular component	Secreted
Domain	Collagen Signal
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 289	273	Complement C1q tumor necrosis factor-related protein 7		PRO_0000003539
Regions
	Domain	38 – 139	102	Collagen-like
	Domain	143 – 279	137	C1q

Sequences

	Sequence		Length	Mass (Da)
	Q9BXJ2-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: A61609FF86D26946	FASTA	289	30,683
	10 20 30 40 50 60 MFVLLYVTSF AICASGQPRG NQLKGENYSP RYICSIPGLP GPPGPPGANG SPGPHGRIGL 70 80 90 100 110 120 PGRDGRDGRK GEKGEKGTAG LRGKTGPLGL AGEKGDQGET GKKGPIGPEG EKGEVGPIGP 130 140 150 160 170 180 PGPKGDRGEQ GDPGLPGVCR CGSIVLKSAF SVGITTSYPE ERLPIIFNKV LFNEGEHYNP 190 200 210 220 230 240 ATGKFICAFP GIYYFSYDIT LANKHLAIGL VHNGQYRIKT FDANTGNHDV ASGSTVIYLQ 250 260 270 280 PEDEVWLEIF FTDQNGLFSD PGWADSLFSG FLLYVDTDYL DSISEDDEL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Homo sapiens complement-c1q tumor necrosis factor-related protein." Piddington C.S., Sheppard P.O., Bishop P., Lasser G.W. Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF329839 mRNA. Translation: AAK17963.1. BC022187 mRNA. Translation: AAH22187.1. BC024015 mRNA. Translation: AAH24015.1.
RefSeq	NP_001128643.1. NP_114117.1.
UniGene	Hs.153714
3D structure databases
HSSP	HSSP built from PDB template 1C28 based on UniProtKB Q60994.
ModBase	Search...
PTM databases
PhosphoSite	Q9BXJ2.
Genome annotation databases
Ensembl	ENSG00000163145. Homo sapiens. [Contig view]
GeneID	114905.
KEGG	hsa:114905.
Organism-specific databases
HGNC	HGNC:14342. C1QTNF7.
HPA	CAB007055.
PharmGKB	PA25634.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOGENOM	Q9BXJ2.
HOVERGEN	Q9BXJ2.
Gene expression databases
ArrayExpress	Q9BXJ2.
CleanEx	HS_C1QTNF7.
GermOnline	ENSG00000163145. Homo sapiens.
Family and domain databases
InterPro	IPR001073. C1q. IPR008160. Collagen. IPR008983. Tumour_necrosis_fac-like. [Graphical view]
Gene3D	G3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
Pfam	PF00386. C1q. 1 hit. PF01391. Collagen. 2 hits. [Graphical view]
PRINTS	PR00007. COMPLEMNTC1Q.
SMART	SM00110. C1Q. 1 hit. [Graphical view]
PROSITE	PS50871. C1Q. 1 hit. [Graphical view]
BLOCKS	Search...
ProtoNet	Search...
Other Resources
NextBio	79426.

Entry information

Entry name

C1QT7_HUMAN

Accession

Primary (citable) accession number: Q9BXJ2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 16, 2002
Last sequence update:	June 1, 2001
Last modified:	November 4, 2008
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)