Q9BXJ2 (C1QT7_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Complement C1q tumor necrosis factor-related protein 7

Gene names

Name:	C1QTNF7
Synonyms:	CTRP7

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Secreted Potential.
Sequence similarities	Contains 1 C1q domain. Contains 1 collagen-like domain.

Ontologies

Keywords
Cellular component	Secreted
Domain	Collagen Signal
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	collagen Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 16	16	Potential
	Chain	17 – 289	273	Complement C1q tumor necrosis factor-related protein 7		PRO_0000003539
Regions
	Domain	38 – 139	102	Collagen-like
	Domain	143 – 279	137	C1q

Sequences

	Sequence		Length	Mass (Da)
	Q9BXJ2 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: A61609FF86D26946	FASTA	289	30,683
	10 20 30 40 50 60 MFVLLYVTSF AICASGQPRG NQLKGENYSP RYICSIPGLP GPPGPPGANG SPGPHGRIGL 70 80 90 100 110 120 PGRDGRDGRK GEKGEKGTAG LRGKTGPLGL AGEKGDQGET GKKGPIGPEG EKGEVGPIGP 130 140 150 160 170 180 PGPKGDRGEQ GDPGLPGVCR CGSIVLKSAF SVGITTSYPE ERLPIIFNKV LFNEGEHYNP 190 200 210 220 230 240 ATGKFICAFP GIYYFSYDIT LANKHLAIGL VHNGQYRIKT FDANTGNHDV ASGSTVIYLQ 250 260 270 280 PEDEVWLEIF FTDQNGLFSD PGWADSLFSG FLLYVDTDYL DSISEDDEL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Homo sapiens complement-c1q tumor necrosis factor-related protein." Piddington C.S., Sheppard P.O., Bishop P., Lasser G.W. Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Trachea.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF329839 mRNA. Translation: AAK17963.1. AK314802 mRNA. Translation: BAG37330.1. BC022187 mRNA. Translation: AAH22187.1. BC024015 mRNA. Translation: AAH24015.1.
IPI	IPI00784310.
RefSeq	NP_001128642.1. NM_001135170.1. NP_001128643.1. NM_001135171.1. NP_114117.1. NM_031911.4.
UniGene	Hs.153714.
3D structure databases
ProteinModelPortal	Q9BXJ2.
SMR	Q9BXJ2. Positions 145-275.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9BXJ2.
PTM databases
PhosphoSite	Q9BXJ2.
Polymorphism databases
DMDM	20177863.
Proteomic databases
PRIDE	Q9BXJ2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000295297; ENSP00000295297; ENSG00000163145. ENST00000382383; ENSP00000371820; ENSG00000163145. ENST00000397700; ENSP00000380812; ENSG00000163145. ENST00000429690; ENSP00000410722; ENSG00000163145. ENST00000442694; ENSP00000388362; ENSG00000163145. ENST00000444304; ENSP00000388914; ENSG00000163145.
GeneID	114905.
KEGG	hsa:114905.
UCSC	uc003gno.1. human.
Organism-specific databases
CTD	114905.
GeneCards	GC04P015283.
HGNC	HGNC:14342. C1QTNF7.
HPA	CAB007055.
neXtProt	NX_Q9BXJ2.
PharmGKB	PA25634.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG04396.
GeneTree	ENSGT00590000082736.
HOGENOM	HBG444750.
HOVERGEN	HBG108220.
InParanoid	Q9BXJ2.
OrthoDB	EOG4MPHR3.
PhylomeDB	Q9BXJ2.
Gene expression databases
ArrayExpress	Q9BXJ2.
Bgee	Q9BXJ2.
CleanEx	HS_C1QTNF7.
Genevestigator	Q9BXJ2.
GermOnline	ENSG00000163145. Homo sapiens.
Family and domain databases
InterPro	IPR001073. C1q. IPR008160. Collagen. IPR008983. Tumour_necrosis_fac-like. [Graphical view]
Gene3D	G3DSA:2.60.120.40. Tumour_necrosis_fac-like. 1 hit.
Pfam	PF00386. C1q. 1 hit. PF01391. Collagen. 2 hits. [Graphical view]
PRINTS	PR00007. COMPLEMNTC1Q.
SMART	SM00110. C1Q. 1 hit. [Graphical view]
SUPFAM	SSF49842. TNF_like. 1 hit.
PROSITE	PS50871. C1Q. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	79426.

Entry information

Entry name

C1QT7_HUMAN

Accession

Primary (citable) accession number: Q9BXJ2
Secondary accession number(s): B2RBT3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 16, 2002
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 84 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.