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Reviewed, UniProtKB/Swiss-Prot Q9BXH5 (TTY6_HUMAN)

Last modified November 24, 2009. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative transcript Y 6 protein
Alternative name(s):
    Testis-specific Y-linked 6
Gene names
Name: TTTY6
Synonyms: TTY6
AND
Name: TTTY6B
OrganismHomo sapiens (Human) [Complete proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length95 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceUncertain.

General annotation (Comments)

Caution

Could be the product of a pseudogene. According to Ref.3, may be a non-coding mRNA.

Ontologies

Keywords
   Coding sequence diversityAlternative splicing
   Technical termComplete proteome
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9BXH5-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9BXH5-2)

The sequence of this isoform differs from the canonical sequence as follows:
     65-65: S → SVLQGLLVKWRNHDKGKSKVEQYSHSSKWTPTGA
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9595Putative transcript Y 6 protein
PRO_0000065687

Natural variations

Alternative sequence651S → SVLQGLLVKWRNHDKGKSKV EQYSHSSKWTPTGA in isoform 2.
VSP_026590

Experimental info

Sequence conflict691V → A in AAT09001. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 886C243D08A0D8FC

FASTA9510,465
        10         20         30         40         50         60 
MHLHRGLLLS QASGNCGIHA VPVICSHWRR RCLDCDGVSE NCSSDFIPER GCVQELSPRG 

        70         80         90 
TGMLSGECVG PHPPLTSLYP HLYLMLWLLK VSVPK 

« Hide

Isoform 2.

Checksum: A3424367913B189B
Show »

FASTA12814,213

References

« Hide 'large scale' references
[1]Zhou G., Ke R., Zhong G., Li H., Shen C., Lin L., Yang S.
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
[2]"The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes."
Skaletsky H., Kuroda-Kawaguchi T., Minx P.J., Cordum H.S., Hillier L.W., Brown L.G., Repping S., Pyntikova T., Ali J., Bieri T., Chinwalla A., Delehaunty A., Delehaunty K., Du H., Fewell G., Fulton L., Fulton R., Graves T.A. expand/collapse author list , Hou S.-F., Latrielle P., Leonard S., Mardis E., Maupin R., McPherson J., Miner T., Nash W., Nguyen C., Ozersky P., Pepin K., Rock S., Rohlfing T., Scott K., Schultz B., Strong C., Tin-Wollam A., Yang S.-P., Waterston R.H., Wilson R.K., Rozen S., Page D.C.
Nature 423:825-837(2003) [PubMed: 12815422] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA / MRNA].
Tissue: Testis.
[3]"Discrimination of non-protein-coding transcripts from protein-coding mRNA."
Frith M.C., Bailey T.L., Kasukawa T., Mignone F., Kummerfeld S.K., Madera M., Sunkara S., Furuno M., Bult C.J., Quackenbush J., Kai C., Kawai J., Carninci P., Hayashizaki Y., Pesole G., Mattick J.S.
RNA Biol. 3:40-48(2006) [PubMed: 17114936] [Abstract]
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

AY597808 mRNA. Translation: AAT09001.1.
AF332237 mRNA. Translation: AAK13487.1.
AC023342 Genomic DNA. No translation available.
IPIIPI00000304.
IPI00472295.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ9BXH5.

Proteomic databases

PRIDEQ9BXH5.

Organism-specific databases

GeneCardsGC0YM022995.
GC0YP022630.
H-InvDBHIX0056676.
HIX0056696.
HGNCHGNC:16483. TTTY6.
HGNC:31887. TTTY6B.
MIM400039. gene.
PharmGKBPA38151.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ9BXH5.

Gene expression databases

CleanExHS_TTTY6.
HS_TTTY6B.
GenevestigatorQ9BXH5.
GermOnlineENSG00000131538. Homo sapiens.
ENSG00000131548. Homo sapiens.

Family and domain databases

ProtoNetSearch...

Other Resources

SOURCESearch...

Entry information

Entry nameTTY6_HUMAN
AccessionPrimary (citable) accession number: Q9BXH5
Secondary accession number(s): Q6PL48
Entry history
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: June 1, 2001
Last modified: November 24, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHPI (Human Proteome Initiative)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome Y

Human chromosome Y: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Alternative products · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents