Reviewed, UniProtKB/Swiss-Prot Q9BXF3 (CECR2_HUMAN)

Names and origin

Protein names

Recommended name:
    Cat eye syndrome critical region protein 2

Gene names

Name:	CECR2
Synonyms:	KIAA1740

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	1484 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis. Ref.7
Subunit structure	Part of the CECR2-containing remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts with LRPPRC. Ref.6
Tissue specificity	Highly expressed in skeletal muscle, thymus, placenta and lung. Expressed at lower level in brain, heart, colon, spleen, kidney.
Miscellaneous	Candidate gene for the Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. Duplication usually takes in the form of a surpernumerary bisatellited isodicentric chromosome, resulting in four copies of the region (represents an inv dup(22)(q11)). CES is characterized clinically by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development.
Sequence similarities	Contains 1 bromo domain.
Sequence caution	The sequence EAW57756.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended/shortened.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Bromodomain
Molecular function	Chromatin regulator
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA fragmentation involved in apoptosis Traceable author statement. Source: HGNC chromatin modification Inferred from electronic annotation. Source: UniProtKB-KW cytokinesis Ref.6 Non-traceable author statement. Source: UniProtKB cytoskeleton organization Ref.6 Non-traceable author statement. Source: UniProtKB vesicle-mediated transport Ref.6 Non-traceable author statement. Source: UniProtKB
Cellular component	nucleus Inferred from direct assay. Source: HGNC
Molecular function	protein binding Inferred from physical interaction. Source: HGNC
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform A (identifier: Q9BXF3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform B (identifier: Q9BXF3-2)

Also known as: CECR2B;

The sequence of this isoform differs from the canonical sequence as follows:
     291-318: Missing.
     519-526: EYTKMSDN → GKQGRSLC
     527-1484: Missing.

Isoform C (identifier: Q9BXF3-3)

The sequence of this isoform differs from the canonical sequence as follows:
     370-389: Missing.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1484	1484	Cat eye syndrome critical region protein 2		PRO_0000211192
Regions
	Domain	451 – 521	71	Bromo
	Compositional bias	333 – 337	5	Poly-Glu
	Compositional bias	611 – 614	4	Poly-Ser
	Compositional bias	1250 – 1253	4	Poly-Pro
Natural variations
	Alternative sequence	291 – 318	28	Missing in isoform B.		VSP_000571
	Alternative sequence	370 – 389	20	Missing in isoform C.		VSP_020407
	Alternative sequence	519 – 526	8	EYTKMSDN → GKQGRSLC in isoform B.		VSP_000572
	Alternative sequence	527 – 1484	958	Missing in isoform B.		VSP_000573
	Natural variant	293	1	R → H: dbSNP rs5747211.		VAR_027411
	Natural variant	632	1	P → L: dbSNP rs1296794.		VAR_048432
	Natural variant	674	1	P → L: dbSNP rs1296794. Ref.1 Ref.5		VAR_027412
Experimental info
	Sequence conflict	352	1	M → I in CAH56122. Ref.4
	Sequence conflict	352	1	M → I in CAH56212. Ref.4
	Sequence conflict	1029	1	S → C in AAK15343. Ref.1
	Sequence conflict	1045	1	W → R in AAK15343. Ref.1
	Sequence conflict	1441	1	M → T in CAH56122. Ref.4
	Sequence conflict	1441	1	M → T in CAH56212. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform A [UniParc]. Last modified September 5, 2006. Version 2. Checksum: 8680DB16A0B90D0D	FASTA	1,484	164,213
	10 20 30 40 50 60 MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR DDVEFISDLI 70 80 90 100 110 120 ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL REASFQDLPL RTRVEILHRL 130 140 150 160 170 180 CDYRLDADDV FDLLKGLDAD SLRVEPLGED NSGALYWYFY GTRMYKEDPV QGKSNGELSL 190 200 210 220 230 240 SRESEGQKNV SSIPGKTGKR RGRPPKRKKL QEEILLSEKQ EENSLASEPQ TRHGSQGPGQ 250 260 270 280 290 300 GTWWLLCQTE EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK GKRPQRTKAE 310 320 330 340 350 360 LHPRWMSDHL SIKPVKQEET PVLTRIEKQK RKEEEEERQI LLAVQKKEQE QMLKEERKRE 370 380 390 400 410 420 LEEKVKAVEG MCSVRVVWRG ACLSTSRPVD RAKRRKLREE RAWLLAQGKE LPPELSHLDP 430 440 450 460 470 480 NSPMREEKKT KDLFELDDDF TAMYKVLDVV KAHKDSWPFL EPVDESYAPN YYQIIKAPMD 490 500 510 520 530 540 ISSMEKKLNG GLYCTKEEFV NDMKTMFRNC RKYNGESSEY TKMSDNLERC FHRAMMKHFP 550 560 570 580 590 600 GEDGDTDEEF WIREDEKREK RRSRAGRSGG SHVWTRSRDP EGSSRKQQPM ENGGKSLPPT 610 620 630 640 650 660 RRAPSSGDDQ SSSSTQPPRE VGTSNGRGFS HPLHCGGTPS QAPFLNQMRP AVPGTFGPLR 670 680 690 700 710 720 GSDPATLYGS SGVPEPHPGE PVQQRQPFTM QPPVGINSLR GPRLGTPEEK QMCGGLTHLS 730 740 750 760 770 780 NMGPHPGSLQ LGQISGPSQD GSMYAPAQFQ PGFIPPRHGG APARPPDFPE SSEIPPSHMY 790 800 810 820 830 840 RSYKYLNRVH SAVWNGNHGA TNQGPLGPDE KPHLGPGPSH QPRTLGHVMD SRVMRPPVPP 850 860 870 880 890 900 NQWTEQSGFL PHGVPSSGYM RPPCKSAGHR LQPPPVPAPS SLFGAPAQAL RGVQGGDSMM 910 920 930 940 950 960 DSPEMIAMQQ LSSRVCPPGV PYHPHQPAHP RLPGPFPQVA HPMSVTVSAP KPALGNPGRA 970 980 990 1000 1010 1020 PENSEAQEPE NDQAEPLPGL EEKPPGVGTS EGVYLTQLPH PTPPLQTDCT RQSSPQERET 1030 1040 1050 1060 1070 1080 VGPELKSSSS ESADNCKAMK GKNPWPSDSS YPGPAAQGCV RDLSTVADRG ALSENGVIGE 1090 1100 1110 1120 1130 1140 ASPCGSEGKG LGSSGSEKLL CPRGRTLQET MPCTGQNAAT PPSTDPGLTG GTVSQFPPLY 1150 1160 1170 1180 1190 1200 MPGLEYPNSA AHYHISPGLQ GVGPVMGGKS PASHPQHFPP RGFQSNHPHS GGFPRYRPPQ 1210 1220 1230 1240 1250 1260 GMRYSYHPPP QPSYHHYQRT PYYACPQSFS DWQRPLHPQG SPSGPPASQP PPPRSLFSDK 1270 1280 1290 1300 1310 1320 NAMASLQGCE TLNAALTSPT RMDAVAAKVP NDGQNPGPEE EKLDESMERP ESPKEFLDLD 1330 1340 1350 1360 1370 1380 NHNAATKRQS SLSASEYLYG TPPPLSSGMG FGSSAFPPHS VMLQTGPPYT PQRPASHFQP 1390 1400 1410 1420 1430 1440 RAYSSPVAAL PPHHPGATQP NGLSQEGPIY RCQEEGLGHF QAVMMEQIGT RSGIRGPFQE 1450 1460 1470 1480 MYRPSGMQMH PVQSQASFPK TPTAATSQEE VPPHKPPTLP LDQS
	Isoform B (CECR2B). Checksum: 40A2A890E9B5B9D6	FASTA	498	58,108
	10 20 30 40 50 60 MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR DDVEFISDLI 70 80 90 100 110 120 ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL REASFQDLPL RTRVEILHRL 130 140 150 160 170 180 CDYRLDADDV FDLLKGLDAD SLRVEPLGED NSGALYWYFY GTRMYKEDPV QGKSNGELSL 190 200 210 220 230 240 SRESEGQKNV SSIPGKTGKR RGRPPKRKKL QEEILLSEKQ EENSLASEPQ TRHGSQGPGQ 250 260 270 280 290 300 GTWWLLCQTE EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK ETPVLTRIEK 310 320 330 340 350 360 QKRKEEEEER QILLAVQKKE QEQMLKEERK RELEEKVKAV EGMCSVRVVW RGACLSTSRP 370 380 390 400 410 420 VDRAKRRKLR EERAWLLAQG KELPPELSHL DPNSPMREEK KTKDLFELDD DFTAMYKVLD 430 440 450 460 470 480 VVKAHKDSWP FLEPVDESYA PNYYQIIKAP MDISSMEKKL NGGLYCTKEE FVNDMKTMFR 490 NCRKYNGESS GKQGRSLC
	Isoform C. Checksum: 3321852BA97D5481	FASTA	1,464	162,067
	10 20 30 40 50 60 MCPEEGGAAG LGELRSWWEV PAIAHFCSLF RTAFRLPDFE IEELEAALHR DDVEFISDLI 70 80 90 100 110 120 ACLLQGCYQR RDITPQTFHS YLEDIINYRW ELEEGKPNPL REASFQDLPL RTRVEILHRL 130 140 150 160 170 180 CDYRLDADDV FDLLKGLDAD SLRVEPLGED NSGALYWYFY GTRMYKEDPV QGKSNGELSL 190 200 210 220 230 240 SRESEGQKNV SSIPGKTGKR RGRPPKRKKL QEEILLSEKQ EENSLASEPQ TRHGSQGPGQ 250 260 270 280 290 300 GTWWLLCQTE EEWRQVTESF RERTSLRERQ LYKLLSEDFL PEICNMIAQK GKRPQRTKAE 310 320 330 340 350 360 LHPRWMSDHL SIKPVKQEET PVLTRIEKQK RKEEEEERQI LLAVQKKEQE QMLKEERKRE 370 380 390 400 410 420 LEEKVKAVED RAKRRKLREE RAWLLAQGKE LPPELSHLDP NSPMREEKKT KDLFELDDDF 430 440 450 460 470 480 TAMYKVLDVV KAHKDSWPFL EPVDESYAPN YYQIIKAPMD ISSMEKKLNG GLYCTKEEFV 490 500 510 520 530 540 NDMKTMFRNC RKYNGESSEY TKMSDNLERC FHRAMMKHFP GEDGDTDEEF WIREDEKREK 550 560 570 580 590 600 RRSRAGRSGG SHVWTRSRDP EGSSRKQQPM ENGGKSLPPT RRAPSSGDDQ SSSSTQPPRE 610 620 630 640 650 660 VGTSNGRGFS HPLHCGGTPS QAPFLNQMRP AVPGTFGPLR GSDPATLYGS SGVPEPHPGE 670 680 690 700 710 720 PVQQRQPFTM QPPVGINSLR GPRLGTPEEK QMCGGLTHLS NMGPHPGSLQ LGQISGPSQD 730 740 750 760 770 780 GSMYAPAQFQ PGFIPPRHGG APARPPDFPE SSEIPPSHMY RSYKYLNRVH SAVWNGNHGA 790 800 810 820 830 840 TNQGPLGPDE KPHLGPGPSH QPRTLGHVMD SRVMRPPVPP NQWTEQSGFL PHGVPSSGYM 850 860 870 880 890 900 RPPCKSAGHR LQPPPVPAPS SLFGAPAQAL RGVQGGDSMM DSPEMIAMQQ LSSRVCPPGV 910 920 930 940 950 960 PYHPHQPAHP RLPGPFPQVA HPMSVTVSAP KPALGNPGRA PENSEAQEPE NDQAEPLPGL 970 980 990 1000 1010 1020 EEKPPGVGTS EGVYLTQLPH PTPPLQTDCT RQSSPQERET VGPELKSSSS ESADNCKAMK 1030 1040 1050 1060 1070 1080 GKNPWPSDSS YPGPAAQGCV RDLSTVADRG ALSENGVIGE ASPCGSEGKG LGSSGSEKLL 1090 1100 1110 1120 1130 1140 CPRGRTLQET MPCTGQNAAT PPSTDPGLTG GTVSQFPPLY MPGLEYPNSA AHYHISPGLQ 1150 1160 1170 1180 1190 1200 GVGPVMGGKS PASHPQHFPP RGFQSNHPHS GGFPRYRPPQ GMRYSYHPPP QPSYHHYQRT 1210 1220 1230 1240 1250 1260 PYYACPQSFS DWQRPLHPQG SPSGPPASQP PPPRSLFSDK NAMASLQGCE TLNAALTSPT 1270 1280 1290 1300 1310 1320 RMDAVAAKVP NDGQNPGPEE EKLDESMERP ESPKEFLDLD NHNAATKRQS SLSASEYLYG 1330 1340 1350 1360 1370 1380 TPPPLSSGMG FGSSAFPPHS VMLQTGPPYT PQRPASHFQP RAYSSPVAAL PPHHPGATQP 1390 1400 1410 1420 1430 1440 NGLSQEGPIY RCQEEGLGHF QAVMMEQIGT RSGIRGPFQE MYRPSGMQMH PVQSQASFPK 1450 1460 TPTAATSQEE VPPHKPPTLP LDQS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere." Footz T.K., Brinkman-Mills P., Banting G.S., Maier S.A., Riazi M.A., Bridgland L.J., Hu S., Birren B., Minoshima S., Shimizu N., Pan H., Nguyen T., Fang F., Fu Y., Ray L., Wu H., Shaull S., Phan S. , Yao Z., Chen F., Huan A., Hu P., Wang Q., Loh P., Qi S., Roe B.A., McDermid H.E. Genome Res. 11:1053-1070(2001) [PubMed: 11381032] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A), VARIANT LEU-674.
[2]	"The DNA sequence of human chromosome 22." Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M. , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H. Nature 402:489-495(1999) [PubMed: 10591208] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed: 17974005] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 36-1484 (ISOFORM C). Tissue: Skeletal muscle.
[5]	"Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." Nagase T., Kikuno R., Hattori A., Kondo Y., Okumura K., Ohara O. DNA Res. 7:347-355(2000) [PubMed: 11214970] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 346-1484 (ISOFORM C), VARIANT LEU-674. Tissue: Brain.
[6]	"Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity." Liu L., McKeehan W.L. Genomics 79:124-136(2002) [PubMed: 11827465] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 168-1484 (ISOFORM B), INTERACTION WITH LRPPRC. Tissue: Liver.
[7]	"CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L." Banting G.S., Barak O., Ames T.M., Burnham A.C., Kardel M.D., Cooch N.S., Davidson C.E., Godbout R., McDermid H.E., Shiekhattar R. Hum. Mol. Genet. 14:513-524(2005) [PubMed: 15640247] [Abstract] Cited for: FUNCTION, IDENTIFICATION IN THE CERF COMPLEX, MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF336133 mRNA. Translation: AAK15343.1. AC004019 Genomic DNA. No translation available. CH471193 Genomic DNA. Translation: EAW57756.1. Different initiation. BX647449 mRNA. Translation: CAH56122.1. Different initiation. AL832377 mRNA. Translation: CAH56212.1. Different initiation. AB051527 mRNA. Translation: BAB21831.1. AF411609 mRNA. Translation: AAL07393.1.
IPI	IPI00215838. IPI00785169. IPI00848350.
RefSeq	NP_113601.2.
UniGene	Hs.658723
3D structure databases
SMR	Q9BXF3. Positions 441-542.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9BXF3.
PTM databases
PhosphoSite	Q9BXF3.
Genome annotation databases
Ensembl	ENST00000262608; ENSP00000262608; ENSG00000099954; Homo sapiens. [Genome view] ENST00000400579; ENSP00000383423; ENSG00000099954; Homo sapiens. [Genome view]
GeneID	27443.
KEGG	hsa:27443.
NMPDR	fig|9606.3.peg.21180.
Organism-specific databases
CTD	27443.
GeneCards	GC22P016328.
H-InvDB	HIX0023032.
HGNC	HGNC:1840. CECR2.
HPA	HPA002943.
MIM	607576. gene.
Orphanet	195. Cat-eye syndrome.
PharmGKB	PA26383.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG15998.
HOGENOM	HBG506250.
HOVERGEN	Q9BXF3.
Gene expression databases
ArrayExpress	Q9BXF3.
Bgee	Q9BXF3.
CleanEx	HS_CECR2.
Genevestigator	Q9BXF3.
GermOnline	ENSG00000099954. Homo sapiens.
Family and domain databases
InterPro	IPR001487. Bromodomain. IPR018359. Bromodomain_CS. [Graphical view]
Gene3D	G3DSA:1.20.920.10. Bromodomain. 1 hit.
Pfam	PF00439. Bromodomain. 1 hit. [Graphical view]
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00297. BROMO. 1 hit. [Graphical view]
PROSITE	PS00633. BROMODOMAIN_1. 1 hit. PS50014. BROMODOMAIN_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	50516.
SOURCE	Search...

Entry information

Entry name

CECR2_HUMAN

Accession

Primary (citable) accession number: Q9BXF3
Secondary accession number(s): A8MS90 , A8MX16, Q658Z4, Q96P58, Q9C0C3

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 16, 2002
Last sequence update:	September 5, 2006
Last modified:	January 19, 2010
This is version 72 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.