Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9BXD5

- NPL_HUMAN

UniProt

Q9BXD5 - NPL_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

N-acetylneuraminate lyase

Gene

NPL

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded (By similarity).By similarity

Catalytic activityi

N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei143 – 1431Involved in proton transfer during cleavageBy similarity
Active sitei173 – 1731Schiff-base intermediate with substrateBy similarity

GO - Molecular functioni

  1. N-acetylneuraminate lyase activity Source: UniProtKB

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
  2. N-acetylneuraminate catabolic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbohydrate metabolism

Keywords - Ligandi

Schiff base

Enzyme and pathway databases

ReactomeiREACT_200874. Sialic acid metabolism.
UniPathwayiUPA00629.

Names & Taxonomyi

Protein namesi
Recommended name:
N-acetylneuraminate lyase (EC:4.1.3.3)
Short name:
NALase
Alternative name(s):
N-acetylneuraminate pyruvate-lyase
N-acetylneuraminic acid aldolase
Sialate lyase
Sialate-pyruvate lyase
Sialic acid aldolase
Sialic acid lyase
Gene namesi
Name:NPL
Synonyms:C1orf13
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 1

Organism-specific databases

HGNCiHGNC:16781. NPL.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25602.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 320320N-acetylneuraminate lyasePRO_0000273352Add
BLAST

Proteomic databases

MaxQBiQ9BXD5.
PaxDbiQ9BXD5.
PRIDEiQ9BXD5.

PTM databases

PhosphoSiteiQ9BXD5.

Expressioni

Tissue specificityi

Isoform 2 is expressed in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocyte.1 Publication

Gene expression databases

BgeeiQ9BXD5.
CleanExiHS_NPL.
GenevestigatoriQ9BXD5.

Organism-specific databases

HPAiHPA028345.

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

BioGridi123344. 2 interactions.
STRINGi9606.ENSP00000258317.

Structurei

3D structure databases

ProteinModelPortaliQ9BXD5.
SMRiQ9BXD5. Positions 8-280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni51 – 522Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the DapA family. NanA subfamily.Curated

Phylogenomic databases

eggNOGiCOG0329.
GeneTreeiENSGT00530000063604.
HOGENOMiHOG000218206.
HOVERGENiHBG082055.
InParanoidiQ9BXD5.
KOiK01639.
OMAiVICRICF.
OrthoDBiEOG7NKKKP.
PhylomeDBiQ9BXD5.
TreeFamiTF353639.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR002220. DapA-like.
[Graphical view]
PANTHERiPTHR12128. PTHR12128. 1 hit.
PfamiPF00701. DHDPS. 1 hit.
[Graphical view]
PIRSFiPIRSF001365. DHDPS. 1 hit.
PRINTSiPR00146. DHPICSNTHASE.

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9BXD5-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAFPKKKLQG LVAATITPMT ENGEINFSVI GQYVDYLVKE QGVKNIFVNG
60 70 80 90 100
TTGEGLSLSV SERRQVAEEW VTKGKDKLDQ VIIHVGALSL KESQELAQHA
110 120 130 140 150
AEIGADGIAV IAPFFLKPWT KDILINFLKE VAAAAPALPF YYYHIPALTG
160 170 180 190 200
VKIRAEELLD GILDKIPTFQ GLKFSDTDLL DFGQCVDQNR QQQFAFLFGV
210 220 230 240 250
DEQLLSALVM GATGAVGSTY NYLGKKTNQM LEAFEQKDFS LALNYQFCIQ
260 270 280 290 300
RFINFVVKLG FGVSQTKAIM TLVSGIPMGP PRLPLQKASR EFTDSAEAKL
310 320
KSLDFLSFTD LKDGNLEAGS
Length:320
Mass (Da):35,163
Last modified:June 1, 2001 - v1
Checksum:iFC0EBA9B05FE9E62
GO
Isoform 2 (identifier: Q9BXD5-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: MAFPKKKLQG...EEWVTKGKDK → MSRAPGILAS...LTVTRLWAER

Show »
Length:301
Mass (Da):33,117
Checksum:iD7168A22A2A7CD14
GO
Isoform 3 (identifier: Q9BXD5-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     260-320: GFGVSQTKAI...LKDGNLEAGS → ENSKLKVSKNQRTLPLGTTNFPFLH

Note: No experimental confirmation available.

Show »
Length:284
Mass (Da):31,562
Checksum:i949BD9DA5FA2DB5C
GO
Isoform 4 (identifier: Q9BXD5-4) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     203-246: Missing.
     260-320: GFGVSQTKAI...LKDGNLEAGS → ENSKLKVSKNQRTLPLGTTNFPFLH

Note: No experimental confirmation available.

Show »
Length:240
Mass (Da):26,765
Checksum:i2DAC394E4ACB1943
GO
Isoform 5 (identifier: Q9BXD5-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     78-109: LDQVIIHVGALSLKESQELAQHAAEIGADGIA → SNHHKLGTIRTTQSRQSSFRRQLKAWHSGSHL
     110-320: Missing.

Note: No experimental confirmation available. May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Show »
Length:109
Mass (Da):12,201
Checksum:i3FEC87DFA591B0E1
GO

Sequence cautioni

The sequence BC042003 differs from that shown. Reason: Frameshift at position 213.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti4 – 41P → S in BC034966. (PubMed:15489334)Curated
Sequence conflicti98 – 981Q → E in BC042003. (PubMed:15489334)Curated
Sequence conflicti212 – 2121A → E in BC042003. (PubMed:15489334)Curated
Sequence conflicti260 – 2601G → V in BAG36036. (PubMed:14702039)Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 7777MAFPK…KGKDK → MSRAPGILASWRRAPSLSVQ KGSQTARHTCHPEVPLGNCF LPVYKASPLTVTRLWAER in isoform 2. 1 PublicationVSP_022518Add
BLAST
Alternative sequencei78 – 10932LDQVI…ADGIA → SNHHKLGTIRTTQSRQSSFR RQLKAWHSGSHL in isoform 5. 1 PublicationVSP_022519Add
BLAST
Alternative sequencei110 – 320211Missing in isoform 5. 1 PublicationVSP_022520Add
BLAST
Alternative sequencei203 – 24644Missing in isoform 4. 1 PublicationVSP_022521Add
BLAST
Alternative sequencei260 – 32061GFGVS…LEAGS → ENSKLKVSKNQRTLPLGTTN FPFLH in isoform 3 and isoform 4. 1 PublicationVSP_022522Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF338436 mRNA. Translation: AAK25795.1.
AY336748 mRNA. Translation: AAQ82432.1.
AK313225 mRNA. Translation: BAG36036.1.
AL355999, AL513344 Genomic DNA. Translation: CAH71702.1.
AL355999, AL513344 Genomic DNA. Translation: CAH71703.1.
AL513344, AL355999 Genomic DNA. Translation: CAI16502.1.
AL513344, AL355999 Genomic DNA. Translation: CAI16503.1.
BC034966 mRNA. No translation available.
BC042003 mRNA. No translation available.
BC058003 mRNA. Translation: AAH58003.1.
BC125051 mRNA. Translation: AAI25052.1.
CCDSiCCDS1350.1. [Q9BXD5-1]
CCDS55666.1. [Q9BXD5-4]
CCDS55667.1. [Q9BXD5-2]
RefSeqiNP_001186979.1. NM_001200050.1. [Q9BXD5-2]
NP_001186980.1. NM_001200051.1. [Q9BXD5-4]
NP_001186985.1. NM_001200056.1. [Q9BXD5-3]
NP_110396.1. NM_030769.2. [Q9BXD5-1]
UniGeneiHs.496969.
Hs.731792.

Genome annotation databases

EnsembliENST00000258317; ENSP00000258317; ENSG00000135838. [Q9BXD5-1]
ENST00000367552; ENSP00000356523; ENSG00000135838. [Q9BXD5-4]
ENST00000367553; ENSP00000356524; ENSG00000135838. [Q9BXD5-1]
ENST00000367554; ENSP00000356525; ENSG00000135838. [Q9BXD5-2]
ENST00000367555; ENSP00000356526; ENSG00000135838. [Q9BXD5-4]
GeneIDi80896.
KEGGihsa:80896.
UCSCiuc001gpo.2. human. [Q9BXD5-2]
uc001gpp.4. human. [Q9BXD5-3]
uc009wyb.3. human. [Q9BXD5-1]
uc009wyc.3. human. [Q9BXD5-4]

Polymorphism databases

DMDMi74752428.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF338436 mRNA. Translation: AAK25795.1 .
AY336748 mRNA. Translation: AAQ82432.1 .
AK313225 mRNA. Translation: BAG36036.1 .
AL355999 , AL513344 Genomic DNA. Translation: CAH71702.1 .
AL355999 , AL513344 Genomic DNA. Translation: CAH71703.1 .
AL513344 , AL355999 Genomic DNA. Translation: CAI16502.1 .
AL513344 , AL355999 Genomic DNA. Translation: CAI16503.1 .
BC034966 mRNA. No translation available.
BC042003 mRNA. No translation available.
BC058003 mRNA. Translation: AAH58003.1 .
BC125051 mRNA. Translation: AAI25052.1 .
CCDSi CCDS1350.1. [Q9BXD5-1 ]
CCDS55666.1. [Q9BXD5-4 ]
CCDS55667.1. [Q9BXD5-2 ]
RefSeqi NP_001186979.1. NM_001200050.1. [Q9BXD5-2 ]
NP_001186980.1. NM_001200051.1. [Q9BXD5-4 ]
NP_001186985.1. NM_001200056.1. [Q9BXD5-3 ]
NP_110396.1. NM_030769.2. [Q9BXD5-1 ]
UniGenei Hs.496969.
Hs.731792.

3D structure databases

ProteinModelPortali Q9BXD5.
SMRi Q9BXD5. Positions 8-280.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 123344. 2 interactions.
STRINGi 9606.ENSP00000258317.

PTM databases

PhosphoSitei Q9BXD5.

Polymorphism databases

DMDMi 74752428.

Proteomic databases

MaxQBi Q9BXD5.
PaxDbi Q9BXD5.
PRIDEi Q9BXD5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000258317 ; ENSP00000258317 ; ENSG00000135838 . [Q9BXD5-1 ]
ENST00000367552 ; ENSP00000356523 ; ENSG00000135838 . [Q9BXD5-4 ]
ENST00000367553 ; ENSP00000356524 ; ENSG00000135838 . [Q9BXD5-1 ]
ENST00000367554 ; ENSP00000356525 ; ENSG00000135838 . [Q9BXD5-2 ]
ENST00000367555 ; ENSP00000356526 ; ENSG00000135838 . [Q9BXD5-4 ]
GeneIDi 80896.
KEGGi hsa:80896.
UCSCi uc001gpo.2. human. [Q9BXD5-2 ]
uc001gpp.4. human. [Q9BXD5-3 ]
uc009wyb.3. human. [Q9BXD5-1 ]
uc009wyc.3. human. [Q9BXD5-4 ]

Organism-specific databases

CTDi 80896.
GeneCardsi GC01P182758.
HGNCi HGNC:16781. NPL.
HPAi HPA028345.
MIMi 611412. gene.
neXtProti NX_Q9BXD5.
PharmGKBi PA25602.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG0329.
GeneTreei ENSGT00530000063604.
HOGENOMi HOG000218206.
HOVERGENi HBG082055.
InParanoidi Q9BXD5.
KOi K01639.
OMAi VICRICF.
OrthoDBi EOG7NKKKP.
PhylomeDBi Q9BXD5.
TreeFami TF353639.

Enzyme and pathway databases

UniPathwayi UPA00629 .
Reactomei REACT_200874. Sialic acid metabolism.

Miscellaneous databases

ChiTaRSi NPL. human.
GenomeRNAii 80896.
NextBioi 71336.
PROi Q9BXD5.
SOURCEi Search...

Gene expression databases

Bgeei Q9BXD5.
CleanExi HS_NPL.
Genevestigatori Q9BXD5.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR002220. DapA-like.
[Graphical view ]
PANTHERi PTHR12128. PTHR12128. 1 hit.
Pfami PF00701. DHDPS. 1 hit.
[Graphical view ]
PIRSFi PIRSF001365. DHDPS. 1 hit.
PRINTSi PR00146. DHPICSNTHASE.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus."
    Sood R., Bonner T.I., Malakowska I., Stephan D.A., Robbins C.M., Connors T.D., Morgenbesser S.D., Su K., Faruque M.U., Pinkett H., Graham C., Baxevanis A.D., Klinger K.W., Landes G.M., Trent J.M., Carpten J.D.
    Genomics 73:211-222(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "A novel splice variant of human gene NPL, mainly expressed in human liver, kidney and peripheral blood leukocyte."
    Wu M., Gu S., Xu J., Zou X., Zheng H., Jin Z., Xie Y., Ji C., Mao Y.
    DNA Seq. 16:137-142(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Teratocarcinoma.
  4. "The DNA sequence and biological annotation of human chromosome 1."
    Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.
    , Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H., Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L., Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J., Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.
    Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 5).
    Tissue: Hypothalamus, Kidney and Testis.
  6. "Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid."
    Bergfeld A.K., Pearce O.M., Diaz S.L., Pham T., Varki A.
    J. Biol. Chem. 287:28865-28881(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: PATHWAY.

Entry informationi

Entry nameiNPL_HUMAN
AccessioniPrimary (citable) accession number: Q9BXD5
Secondary accession number(s): B2R839
, Q4G0Q8, Q4G0Z2, Q64L88, Q6PEL0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3