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Q9BXC0

- HCAR1_HUMAN

UniProt

Q9BXC0 - HCAR1_HUMAN

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Protein

Hydroxycarboxylic acid receptor 1

Gene

HCAR1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.1 Publication

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW

GO - Biological processi

  1. response to estradiol Source: BHF-UCL
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

ReactomeiREACT_163785. Hydroxycarboxylic acid-binding receptors.
REACT_19231. G alpha (i) signalling events.

Protein family/group databases

TCDBi9.A.14.13.4. the g-protein-coupled receptor (gpcr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Hydroxycarboxylic acid receptor 1
Alternative name(s):
G-protein coupled receptor 104
G-protein coupled receptor 81
Gene namesi
Name:HCAR1
Synonyms:GPR104, GPR81, HCA1
ORF Names:FKSG80
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 12

Organism-specific databases

HGNCiHGNC:4532. HCAR1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2121ExtracellularSequence AnalysisAdd
BLAST
Transmembranei22 – 4221Helical; Name=1Sequence AnalysisAdd
BLAST
Topological domaini43 – 497CytoplasmicSequence Analysis
Transmembranei50 – 7021Helical; Name=2Sequence AnalysisAdd
BLAST
Topological domaini71 – 8919ExtracellularSequence AnalysisAdd
BLAST
Transmembranei90 – 11021Helical; Name=3Sequence AnalysisAdd
BLAST
Topological domaini111 – 13020CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei131 – 15121Helical; Name=4Sequence AnalysisAdd
BLAST
Topological domaini152 – 18231ExtracellularSequence AnalysisAdd
BLAST
Transmembranei183 – 20321Helical; Name=5Sequence AnalysisAdd
BLAST
Topological domaini204 – 22017CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei221 – 24121Helical; Name=6Sequence AnalysisAdd
BLAST
Topological domaini242 – 26120ExtracellularSequence AnalysisAdd
BLAST
Transmembranei262 – 28120Helical; Name=7Sequence AnalysisAdd
BLAST
Topological domaini282 – 34665CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: Reactome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi99 – 991R → A: Diminishes the response to L-lactate. 1 Publication
Mutagenesisi233 – 2331Y → A: Diminishes the response to L-lactate. 1 Publication
Mutagenesisi240 – 2401R → A: Diminishes the response to L-lactate. 1 Publication
Mutagenesisi267 – 2671T → A: Diminishes the response to L-lactate. 1 Publication

Organism-specific databases

PharmGKBiPA28925.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Hydroxycarboxylic acid receptor 1PRO_0000069586Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi3 – 31N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi88 ↔ 165PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9BXC0.
PRIDEiQ9BXC0.

PTM databases

PhosphoSiteiQ9BXC0.

Expressioni

Tissue specificityi

Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.2 Publications

Gene expression databases

BgeeiQ9BXC0.
CleanExiHS_GPR81.
GenevestigatoriQ9BXC0.

Interactioni

Protein-protein interaction databases

IntActiQ9BXC0. 1 interaction.
STRINGi9606.ENSP00000349478.

Structurei

3D structure databases

ProteinModelPortaliQ9BXC0.
SMRiQ9BXC0. Positions 18-285.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG148165.
GeneTreeiENSGT00510000046798.
HOVERGENiHBG051680.
InParanoidiQ9BXC0.
KOiK08401.
OMAiLAMNRAG.
OrthoDBiEOG7R56SR.
PhylomeDBiQ9BXC0.
TreeFamiTF330775.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR028016. HCAR1_rcpt.
[Graphical view]
PANTHERiPTHR24231:SF29. PTHR24231:SF29. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BXC0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYNGSCCRIE GDTISQVMPP LLIVAFVLGA LGNGVALCGF CFHMKTWKPS
60 70 80 90 100
TVYLFNLAVA DFLLMICLPF RTDYYLRRRH WAFGDIPCRV GLFTLAMNRA
110 120 130 140 150
GSIVFLTVVA ADRYFKVVHP HHAVNTISTR VAAGIVCTLW ALVILGTVYL
160 170 180 190 200
LLENHLCVQE TAVSCESFIM ESANGWHDIM FQLEFFMPLG IILFCSFKIV
210 220 230 240 250
WSLRRRQQLA RQARMKKATR FIMVVAIVFI TCYLPSVSAR LYFLWTVPSS
260 270 280 290 300
ACDPSVHGAL HITLSFTYMN SMLDPLVYYF SSPSFPKFYN KLKICSLKPK
310 320 330 340
QPGHSKTQRP EEMPISNLGR RSCISVANSF QSQSDGQWDP HIVEWH
Length:346
Mass (Da):39,295
Last modified:June 1, 2001 - v1
Checksum:iE0DB114EEB3A47A5
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti38 – 381C → Y in AAH95506. (PubMed:15489334)Curated
Sequence conflicti113 – 1131R → K in AAH66883. (PubMed:15489334)Curated
Sequence conflicti187 – 1871M → I in AAH95506. (PubMed:15489334)Curated
Sequence conflicti213 – 2131A → T in AAH95506. (PubMed:15489334)Curated
Sequence conflicti222 – 2221I → T in AAH95506. (PubMed:15489334)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti43 – 431H → Q.1 Publication
Corresponds to variant rs35292336 [ dbSNP | Ensembl ].
VAR_025151
Natural varianti253 – 2531D → E.1 Publication
VAR_025152
Natural varianti253 – 2531D → H.
Corresponds to variant rs36124671 [ dbSNP | Ensembl ].
VAR_061218

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF411110 Genomic DNA. Translation: AAL26481.1.
EU809458 mRNA. Translation: ACJ03844.1.
AF345568 mRNA. Translation: AAK29071.1.
AB065866 Genomic DNA. Translation: BAC06084.1.
AY507143 mRNA. Translation: AAR92485.1.
AK313955 mRNA. Translation: BAG36671.1.
AB083631 Genomic DNA. Translation: BAB89344.1.
DQ157221 Genomic DNA. Translation: AAZ67915.1.
AC026333 Genomic DNA. No translation available.
CH471054 Genomic DNA. Translation: EAW98337.1.
BC066881 mRNA. Translation: AAH66881.1.
BC066882 mRNA. Translation: AAH66882.1.
BC066883 mRNA. Translation: AAH66883.1.
BC067484 mRNA. Translation: AAH67484.1.
BC095506 mRNA. Translation: AAH95506.1.
CCDSiCCDS9236.1.
RefSeqiNP_115943.1. NM_032554.3.
UniGeneiHs.610873.
Hs.711001.

Genome annotation databases

EnsembliENST00000432564; ENSP00000389255; ENSG00000196917.
GeneIDi27198.
KEGGihsa:27198.
UCSCiuc001ucz.3. human.

Polymorphism databases

DMDMi47117701.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Web resourcesi

SeattleSNPs

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF411110 Genomic DNA. Translation: AAL26481.1 .
EU809458 mRNA. Translation: ACJ03844.1 .
AF345568 mRNA. Translation: AAK29071.1 .
AB065866 Genomic DNA. Translation: BAC06084.1 .
AY507143 mRNA. Translation: AAR92485.1 .
AK313955 mRNA. Translation: BAG36671.1 .
AB083631 Genomic DNA. Translation: BAB89344.1 .
DQ157221 Genomic DNA. Translation: AAZ67915.1 .
AC026333 Genomic DNA. No translation available.
CH471054 Genomic DNA. Translation: EAW98337.1 .
BC066881 mRNA. Translation: AAH66881.1 .
BC066882 mRNA. Translation: AAH66882.1 .
BC066883 mRNA. Translation: AAH66883.1 .
BC067484 mRNA. Translation: AAH67484.1 .
BC095506 mRNA. Translation: AAH95506.1 .
CCDSi CCDS9236.1.
RefSeqi NP_115943.1. NM_032554.3.
UniGenei Hs.610873.
Hs.711001.

3D structure databases

ProteinModelPortali Q9BXC0.
SMRi Q9BXC0. Positions 18-285.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q9BXC0. 1 interaction.
STRINGi 9606.ENSP00000349478.

Chemistry

BindingDBi Q9BXC0.
ChEMBLi CHEMBL1075101.
GuidetoPHARMACOLOGYi 311.

Protein family/group databases

TCDBi 9.A.14.13.4. the g-protein-coupled receptor (gpcr) family.
GPCRDBi Search...

PTM databases

PhosphoSitei Q9BXC0.

Polymorphism databases

DMDMi 47117701.

Proteomic databases

PaxDbi Q9BXC0.
PRIDEi Q9BXC0.

Protocols and materials databases

DNASUi 27198.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000432564 ; ENSP00000389255 ; ENSG00000196917 .
GeneIDi 27198.
KEGGi hsa:27198.
UCSCi uc001ucz.3. human.

Organism-specific databases

CTDi 27198.
GeneCardsi GC12M123104.
H-InvDB HIX0026348.
HGNCi HGNC:4532. HCAR1.
MIMi 606923. gene.
neXtProti NX_Q9BXC0.
PharmGKBi PA28925.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG148165.
GeneTreei ENSGT00510000046798.
HOVERGENi HBG051680.
InParanoidi Q9BXC0.
KOi K08401.
OMAi LAMNRAG.
OrthoDBi EOG7R56SR.
PhylomeDBi Q9BXC0.
TreeFami TF330775.

Enzyme and pathway databases

Reactomei REACT_163785. Hydroxycarboxylic acid-binding receptors.
REACT_19231. G alpha (i) signalling events.

Miscellaneous databases

GeneWikii GPR81.
GenomeRNAii 27198.
NextBioi 50062.
PROi Q9BXC0.
SOURCEi Search...

Gene expression databases

Bgeei Q9BXC0.
CleanExi HS_GPR81.
Genevestigatori Q9BXC0.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR028016. HCAR1_rcpt.
[Graphical view ]
PANTHERi PTHR24231:SF29. PTHR24231:SF29. 1 hit.
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Discovery and mapping of ten novel G protein-coupled receptor genes."
    Lee D.K., Nguyen T., Lynch K.R., Cheng R., Vanti W.B., Arkhitko O., Lewis T., Evans J.F., George S.R., O'Dowd B.F.
    Gene 275:83-91(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], TISSUE SPECIFICITY.
  2. "Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81."
    Liu C., Wu J., Zhu J., Kuei C., Yu J., Shelton J., Sutton S.W., Li X., Yun S.J., Mirzadegan T., Mazur C., Kamme F., Lovenberg T.W.
    J. Biol. Chem. 284:2811-2822(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, MUTAGENESIS OF ARG-99; TYR-233; ARG-240 AND THR-267.
  3. "Molecular cloning of FKSG80, a novel gene encoding a putative chemokine receptor."
    Wang Y.-G., Gong L.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  4. "Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
    Suwa M., Sato T., Okouchi I., Arita M., Futami K., Matsumoto S., Tsutsumi S., Aburatani H., Asai K., Akiyama Y.
    Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  5. "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
    King M.M., Aronstam R.S., Sharma S.V.
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Spleen.
  7. "Identification of G protein-coupled receptor genes from the human genome sequence."
    Takeda S., Kadowaki S., Haga T., Takaesu H., Mitaku S.
    FEBS Lett. 520:97-101(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. SeattleSNPs variation discovery resource
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS GLN-43 AND GLU-253.
  9. "The finished DNA sequence of human chromosome 12."
    Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
    , Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., Kucherlapati R., Weinstock G., Gibbs R.A.
    Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  10. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  11. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  12. "International union of basic and clinical pharmacology. LXXXII: nomenclature and classification of hydroxy-carboxylic acid receptors (GPR81, GPR109A, and GPR109B)."
    Offermanns S., Colletti S.L., Lovenberg T.W., Semple G., Wise A., Ijzerman A.P.
    Pharmacol. Rev. 63:269-290(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NOMENCLATURE.

Entry informationi

Entry nameiHCAR1_HUMAN
AccessioniPrimary (citable) accession number: Q9BXC0
Secondary accession number(s): B2R9X4
, Q3Y5J3, Q4VBN1, Q6NXU5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: June 1, 2001
Last modified: November 26, 2014
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3