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Q9BWU0

- NADAP_HUMAN

UniProt

Q9BWU0 - NADAP_HUMAN

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Protein

Kanadaptin

Gene

SLC4A1AP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli

Functioni

Protein family/group databases

TCDBi3.A.18.1.2. the nuclear mrna exporter (mrna-e) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Kanadaptin
Alternative name(s):
Human lung cancer oncogene 3 protein
Short name:
HLC-3
Kidney anion exchanger adapter protein
Solute carrier family 4 anion exchanger member 1 adapter protein
Gene namesi
ORF Names:HLC3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:13813. SLC4A1AP.

Subcellular locationi

Nucleus 1 Publication. Cytoplasm 1 Publication
Note: Mainly nuclear. Small amounts are found in the cytoplasm.

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37811.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 796796KanadaptinPRO_0000076268Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei82 – 821Phosphoserine1 Publication
Modified residuei312 – 3121Phosphoserine4 Publications
Modified residuei466 – 4661Phosphoserine4 Publications
Modified residuei530 – 5301Phosphoserine1 Publication
Modified residuei712 – 7121Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ9BWU0.
PaxDbiQ9BWU0.
PRIDEiQ9BWU0.

PTM databases

PhosphoSiteiQ9BWU0.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

BgeeiQ9BWU0.
CleanExiHS_SLC4A1AP.
ExpressionAtlasiQ9BWU0. baseline.
GenevestigatoriQ9BWU0.

Organism-specific databases

HPAiHPA036680.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
ILKQ134188EBI-1999704,EBI-747644

Protein-protein interaction databases

BioGridi116605. 17 interactions.
IntActiQ9BWU0. 5 interactions.
STRINGi9606.ENSP00000323837.

Structurei

Secondary structure

1
796
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi168 – 1736
Beta strandi176 – 1827
Beta strandi187 – 1948
Beta strandi197 – 2004
Beta strandi211 – 2166
Beta strandi231 – 2355
Beta strandi242 – 2443
Beta strandi262 – 2654
Beta strandi269 – 2757

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4H87X-ray1.55A/B149-276[»]
ProteinModelPortaliQ9BWU0.
SMRiQ9BWU0. Positions 149-276.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini189 – 24961FHAPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili497 – 53034Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi644 – 71572Glu-richAdd
BLAST

Sequence similaritiesi

Contains 1 FHA domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG251732.
GeneTreeiENSGT00730000110659.
HOGENOMiHOG000008002.
HOVERGENiHBG052984.
InParanoidiQ9BWU0.
OMAiELEFEYE.
OrthoDBiEOG7V1FQC.
PhylomeDBiQ9BWU0.
TreeFamiTF314854.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
InterProiIPR014720. dsRNA-bd_dom.
IPR000253. FHA_dom.
IPR008984. SMAD_FHA_domain.
[Graphical view]
PfamiPF00035. dsrm. 1 hit.
PF00498. FHA. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 1 hit.
SM00240. FHA. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiPS50006. FHA_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9BWU0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLAPLRNAPG REGATSPSPP TDATGSLGEW DVDRNVKTEG WVSKERISKL
60 70 80 90 100
HRLRMADILS QSETLASQDL SGDFKKPALP VSPAARSKAP ASSSSNPEEV
110 120 130 140 150
QKEGPTALQD SNSGEPDIPP PQPDCGDFRS LQEEQSRPPT AVSSPGGPAR
160 170 180 190 200
APPYQEPPWG GPATAPYSLE TLKGGTILGT RSLKGTSYCL FGRLSGCDVC
210 220 230 240 250
LEHPSVSRYH AVLQHRASGP DGECDSNGPG FYLYDLGSTH GTFLNKTRIP
260 270 280 290 300
PRTYCRVHVG HVVRFGGSTR LFILQGPEED REAESELTVT QLKELRKQQQ
310 320 330 340 350
ILLEKKMLGE DSDEEEEMDT SERKINAGSQ DDEMGCTWGM GEDAVEDDAE
360 370 380 390 400
ENPIVLEFQQ EREAFYIKDP KKALQGFFDR EGEELEYEFD EQGHSTWLCR
410 420 430 440 450
VRLPVDDSTG KQLVAEAIHS GKKKEAMIQC SLEACRILDT LGLLRQEAVS
460 470 480 490 500
RKRKAKNWED EDFYDSDDDT FLDRTGLIEK KRLNRMKKAG KIDEKPETFE
510 520 530 540 550
SLVAKLNDAE RELSEISERL KASSQVLSES PSQDSLDAFM SEMKSGSTLD
560 570 580 590 600
GVSRKKLHLR TFELRKEQQR LKGLIKIVKP AEIPELKKTE TQTTGAENKA
610 620 630 640 650
KKLTLPLFGA MKGGSKFKLK TGTVGKLPPK RPELPPTLMR MKDEPEVEEE
660 670 680 690 700
EEEEEEEEKE KEEHEKKKLE DGSLSRPQPE IEPEAAVQEM RPPTDLTHFK
710 720 730 740 750
ETQTHENMSQ LSEEEQNKDY QDCSKTTSLC AGPSASKNEY EKSRGELKKK
760 770 780 790
KTPGPGKLPP TLSSKYPEDD PDYCVWVPPE GQSGDGRTHL NDKYGY
Length:796
Mass (Da):88,814
Last modified:June 1, 2001 - v1
Checksum:iEE0F560648DA39EF
GO

Sequence cautioni

The sequence AAN12269.1 differs from that shown. Reason: Erroneous initiation.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1155SNSGE → PIAKP in AAN12269. 1 PublicationCurated
Sequence conflicti309 – 3091G → R in AAK29177. (PubMed:14702039)Curated
Sequence conflicti359 – 3591Q → R in AAH98358. (PubMed:15489334)Curated
Sequence conflicti373 – 3731A → V in AAK29177. (PubMed:14702039)Curated
Sequence conflicti444 – 4441L → I in AAN12269. 1 PublicationCurated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti139 – 1391P → T.3 Publications
Corresponds to variant rs9678851 [ dbSNP | Ensembl ].
VAR_024748
Natural varianti181 – 1811R → C.
Corresponds to variant rs9679004 [ dbSNP | Ensembl ].
VAR_051219

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY028435 mRNA. Translation: AAK29177.1.
AK001486 mRNA. Translation: BAA91718.1.
AC074091 Genomic DNA. Translation: AAX93203.1.
CH471053 Genomic DNA. Translation: EAX00555.1.
BC098302 mRNA. Translation: AAH98302.1.
BC098358 mRNA. Translation: AAH98358.1.
BC099711 mRNA. Translation: AAH99711.1.
BC099739 mRNA. Translation: AAH99739.1.
AY117688 mRNA. Translation: AAN12269.1. Different initiation.
CCDSiCCDS33166.1.
RefSeqiNP_060628.2. NM_018158.2.
UniGeneiHs.306000.

Genome annotation databases

EnsembliENST00000326019; ENSP00000323837; ENSG00000163798.
ENST00000613058; ENSP00000479964; ENSG00000163798.
GeneIDi22950.
KEGGihsa:22950.
UCSCiuc002rlk.4. human.

Polymorphism databases

DMDMi74724887.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Web resourcesi

Wikipedia

Band 3 entry

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY028435 mRNA. Translation: AAK29177.1 .
AK001486 mRNA. Translation: BAA91718.1 .
AC074091 Genomic DNA. Translation: AAX93203.1 .
CH471053 Genomic DNA. Translation: EAX00555.1 .
BC098302 mRNA. Translation: AAH98302.1 .
BC098358 mRNA. Translation: AAH98358.1 .
BC099711 mRNA. Translation: AAH99711.1 .
BC099739 mRNA. Translation: AAH99739.1 .
AY117688 mRNA. Translation: AAN12269.1 . Different initiation.
CCDSi CCDS33166.1.
RefSeqi NP_060628.2. NM_018158.2.
UniGenei Hs.306000.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4H87 X-ray 1.55 A/B 149-276 [» ]
ProteinModelPortali Q9BWU0.
SMRi Q9BWU0. Positions 149-276.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 116605. 17 interactions.
IntActi Q9BWU0. 5 interactions.
STRINGi 9606.ENSP00000323837.

Protein family/group databases

TCDBi 3.A.18.1.2. the nuclear mrna exporter (mrna-e) family.

PTM databases

PhosphoSitei Q9BWU0.

Polymorphism databases

DMDMi 74724887.

Proteomic databases

MaxQBi Q9BWU0.
PaxDbi Q9BWU0.
PRIDEi Q9BWU0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000326019 ; ENSP00000323837 ; ENSG00000163798 .
ENST00000613058 ; ENSP00000479964 ; ENSG00000163798 .
GeneIDi 22950.
KEGGi hsa:22950.
UCSCi uc002rlk.4. human.

Organism-specific databases

CTDi 22950.
GeneCardsi GC02P027886.
H-InvDB HIX0001931.
HGNCi HGNC:13813. SLC4A1AP.
HPAi HPA036680.
MIMi 602655. gene.
neXtProti NX_Q9BWU0.
PharmGKBi PA37811.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG251732.
GeneTreei ENSGT00730000110659.
HOGENOMi HOG000008002.
HOVERGENi HBG052984.
InParanoidi Q9BWU0.
OMAi ELEFEYE.
OrthoDBi EOG7V1FQC.
PhylomeDBi Q9BWU0.
TreeFami TF314854.

Miscellaneous databases

ChiTaRSi SLC4A1AP. human.
GenomeRNAii 22950.
NextBioi 43719.
PROi Q9BWU0.
SOURCEi Search...

Gene expression databases

Bgeei Q9BWU0.
CleanExi HS_SLC4A1AP.
ExpressionAtlasi Q9BWU0. baseline.
Genevestigatori Q9BWU0.

Family and domain databases

Gene3Di 2.60.200.20. 1 hit.
InterProi IPR014720. dsRNA-bd_dom.
IPR000253. FHA_dom.
IPR008984. SMAD_FHA_domain.
[Graphical view ]
Pfami PF00035. dsrm. 1 hit.
PF00498. FHA. 1 hit.
[Graphical view ]
SMARTi SM00358. DSRM. 1 hit.
SM00240. FHA. 1 hit.
[Graphical view ]
SUPFAMi SSF49879. SSF49879. 1 hit.
PROSITEi PS50006. FHA_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Human kanadaptin and kidney anion exchanger 1 (kAE1) do not interact in transfected HEK 293 cells."
    Kittanakom S., Keskanokwong T., Akkarapatumwong V., Yenchitsomanus P.-T., Reithmeier R.A.F.
    Mol. Membr. Biol. 21:395-402(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT THR-139.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT THR-139.
  6. "Identification of a new oncogene in human lung cancer."
    Kim J.W.
    Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 111-796.
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  8. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  9. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-312; SER-466 AND SER-530, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  10. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-312 AND SER-466, VARIANT [LARGE SCALE ANALYSIS] THR-139, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-82; SER-312; SER-466 AND SER-712, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-312 AND SER-466, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  15. "Crystal structure of a FHA domain of kanadaptin (SLC4A1AP) from Homo sapiens at 1.55 A resolution."
    Joint center for structural genomics (JCSG)
    Submitted (OCT-2012) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 149-276.

Entry informationi

Entry nameiNADAP_HUMAN
AccessioniPrimary (citable) accession number: Q9BWU0
Secondary accession number(s): A6NJ39
, Q4KMT1, Q4KMX0, Q7Z5Q9, Q9NVN2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

PubMed:15764369 initially suggested a role in targeting SLC4A1 (kidney anion exchanger 1) to the plasma membrane; it does not seem to do so as it does not interact with SLC4A1 and has no effect on SLC4A1 trafficking.Curated

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  6. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3