Q9BWQ6 (YIPF2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein YIPF2

Alternative name(s):
YIP1 family member 2

Gene names

Name:

YIPF2

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the YIP1 family.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW transport vesicle Inferred from direct assay. Source: LIFEdb
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 316	316	Protein YIPF2		PRO_0000241454
Regions
	Topological domain	1 – 124	124	Cytoplasmic Potential
	Transmembrane	125 – 145	21	Helical; Potential
	Topological domain	146 – 163	18	Lumenal Potential
	Transmembrane	164 – 184	21	Helical; Potential
	Topological domain	185 – 196	12	Cytoplasmic Potential
	Transmembrane	197 – 219	23	Helical; Potential
	Topological domain	220 – 231	12	Lumenal Potential
	Transmembrane	232 – 252	21	Helical; Potential
	Topological domain	253 – 256	4	Cytoplasmic Potential
	Transmembrane	257 – 277	21	Helical; Potential
	Topological domain	278 – 316	39	Lumenal Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9BWQ6 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 274E5F2D07EA1A75	FASTA	316	35,151
	10 20 30 40 50 60 MASADELTFH EFEEATNLLA DTPDAATTSR SDQLTPQGHV AVAVGSGGSY GAEDEVEEES 70 80 90 100 110 120 DKAALLQEQQ QQQQPGFWTF SYYQSFFDVD TSQVLDRIKG SLLPRPGHNF VRHHLRNRPD 130 140 150 160 170 180 LYGPFWICAT LAFVLAVTGN LTLVLAQRRD PSIHYSPQFH KVTVAGISIY CYAWLVPLAL 190 200 210 220 230 240 WGFLRWRKGV QERMGPYTFL ETVCIYGYSL FVFIPMVVLW LIPVPWLQWL FGALALGLSA 250 260 270 280 290 300 AGLVFTLWPV VREDTRLVAT VLLSVVVLLH ALLAMGCKLY FFQSLPPENV APPPQITSLP 310 SNIALSPTLP QSLAPS

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Renal cell carcinoma and Rhabdomyosarcoma.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC000056 mRNA. Translation: AAH00056.1. BC013014 mRNA. Translation: AAH13014.1.
IPI	IPI00031493.
RefSeq	NP_076934.1. NM_024029.3.
UniGene	Hs.720136.
3D structure databases
ProteinModelPortal	Q9BWQ6.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9BWQ6. 4 interactions.
STRING	Q9BWQ6.
Polymorphism databases
DMDM	74733454.
Proteomic databases
PRIDE	Q9BWQ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000253031; ENSP00000253031; ENSG00000130733. ENST00000393508; ENSP00000377144; ENSG00000130733.
GeneID	78992.
KEGG	hsa:78992.
UCSC	uc002mqb.1. human.
Organism-specific databases
CTD	78992.
GeneCards	GC19M011033.
HGNC	HGNC:28476. YIPF2.
HPA	HPA019902.
neXtProt	NX_Q9BWQ6.
PharmGKB	PA142670556.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG09288.
GeneTree	ENSGT00390000010157.
HOGENOM	HBG717249.
HOVERGEN	HBG056746.
InParanoid	Q9BWQ6.
OMA	QPGFWTF.
OrthoDB	EOG4BG8WT.
PhylomeDB	Q9BWQ6.
Gene expression databases
ArrayExpress	Q9BWQ6.
Bgee	Q9BWQ6.
CleanEx	HS_YIPF2.
Genevestigator	Q9BWQ6.
GermOnline	ENSG00000130733. Homo sapiens.
Family and domain databases
InterPro	IPR006977. Yip1. [Graphical view]
Pfam	PF04893. Yip1. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	67582.

Entry information

Entry name

YIPF2_HUMAN

Accession

Primary (citable) accession number: Q9BWQ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	June 1, 2001
Last modified:	January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.