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Protein

Protein YIPF2

Gene

YIPF2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIPF2
Alternative name(s):
YIP1 family member 2
Gene namesi
Name:YIPF2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:28476. YIPF2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini2 – 124123CytoplasmicSequence analysisAdd
BLAST
Transmembranei125 – 14521HelicalSequence analysisAdd
BLAST
Topological domaini146 – 16318LumenalSequence analysisAdd
BLAST
Transmembranei164 – 18421HelicalSequence analysisAdd
BLAST
Topological domaini185 – 19612CytoplasmicSequence analysisAdd
BLAST
Transmembranei197 – 21923HelicalSequence analysisAdd
BLAST
Topological domaini220 – 23112LumenalSequence analysisAdd
BLAST
Transmembranei232 – 25221HelicalSequence analysisAdd
BLAST
Topological domaini253 – 2564CytoplasmicSequence analysis
Transmembranei257 – 27721HelicalSequence analysisAdd
BLAST
Topological domaini278 – 31639LumenalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA142670556.

Polymorphism and mutation databases

BioMutaiYIPF2.
DMDMi74733454.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedCombined sources
Chaini2 – 316315Protein YIPF2PRO_0000241454Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineCombined sources

Keywords - PTMi

Acetylation

Proteomic databases

EPDiQ9BWQ6.
MaxQBiQ9BWQ6.
PaxDbiQ9BWQ6.
PeptideAtlasiQ9BWQ6.
PRIDEiQ9BWQ6.

PTM databases

iPTMnetiQ9BWQ6.
PhosphoSiteiQ9BWQ6.

Expressioni

Gene expression databases

BgeeiENSG00000130733.
CleanExiHS_YIPF2.
ExpressionAtlasiQ9BWQ6. baseline and differential.
GenevisibleiQ9BWQ6. HS.

Organism-specific databases

HPAiHPA019902.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
RNF185Q96GF13EBI-751204,EBI-2340249
RNF5Q999423EBI-751204,EBI-348482
YIPF6Q96EC86EBI-751204,EBI-751210

Protein-protein interaction databases

BioGridi122463. 8 interactions.
IntActiQ9BWQ6. 7 interactions.
MINTiMINT-3062783.
STRINGi9606.ENSP00000253031.

Structurei

3D structure databases

ProteinModelPortaliQ9BWQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIP1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3114. Eukaryota.
ENOG4110TJR. LUCA.
GeneTreeiENSGT00390000010157.
HOGENOMiHOG000231137.
HOVERGENiHBG056746.
InParanoidiQ9BWQ6.
OMAiRERAGPY.
OrthoDBiEOG091G0JY5.
PhylomeDBiQ9BWQ6.

Family and domain databases

InterProiIPR006977. Yip1.
[Graphical view]
PfamiPF04893. Yip1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9BWQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASADELTFH EFEEATNLLA DTPDAATTSR SDQLTPQGHV AVAVGSGGSY
60 70 80 90 100
GAEDEVEEES DKAALLQEQQ QQQQPGFWTF SYYQSFFDVD TSQVLDRIKG
110 120 130 140 150
SLLPRPGHNF VRHHLRNRPD LYGPFWICAT LAFVLAVTGN LTLVLAQRRD
160 170 180 190 200
PSIHYSPQFH KVTVAGISIY CYAWLVPLAL WGFLRWRKGV QERMGPYTFL
210 220 230 240 250
ETVCIYGYSL FVFIPMVVLW LIPVPWLQWL FGALALGLSA AGLVFTLWPV
260 270 280 290 300
VREDTRLVAT VLLSVVVLLH ALLAMGCKLY FFQSLPPENV APPPQITSLP
310
SNIALSPTLP QSLAPS
Length:316
Mass (Da):35,151
Last modified:June 1, 2001 - v1
Checksum:i274E5F2D07EA1A75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC000056 mRNA. Translation: AAH00056.1.
BC013014 mRNA. Translation: AAH13014.1.
CCDSiCCDS12251.1.
RefSeqiNP_001308368.1. NM_001321439.1.
NP_076934.1. NM_024029.4.
XP_011526572.1. XM_011528270.2.
UniGeneiHs.164026.
Hs.720136.

Genome annotation databases

EnsembliENST00000253031; ENSP00000253031; ENSG00000130733.
ENST00000586748; ENSP00000466055; ENSG00000130733.
GeneIDi78992.
KEGGihsa:78992.
UCSCiuc002mqb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC000056 mRNA. Translation: AAH00056.1.
BC013014 mRNA. Translation: AAH13014.1.
CCDSiCCDS12251.1.
RefSeqiNP_001308368.1. NM_001321439.1.
NP_076934.1. NM_024029.4.
XP_011526572.1. XM_011528270.2.
UniGeneiHs.164026.
Hs.720136.

3D structure databases

ProteinModelPortaliQ9BWQ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122463. 8 interactions.
IntActiQ9BWQ6. 7 interactions.
MINTiMINT-3062783.
STRINGi9606.ENSP00000253031.

PTM databases

iPTMnetiQ9BWQ6.
PhosphoSiteiQ9BWQ6.

Polymorphism and mutation databases

BioMutaiYIPF2.
DMDMi74733454.

Proteomic databases

EPDiQ9BWQ6.
MaxQBiQ9BWQ6.
PaxDbiQ9BWQ6.
PeptideAtlasiQ9BWQ6.
PRIDEiQ9BWQ6.

Protocols and materials databases

DNASUi78992.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000253031; ENSP00000253031; ENSG00000130733.
ENST00000586748; ENSP00000466055; ENSG00000130733.
GeneIDi78992.
KEGGihsa:78992.
UCSCiuc002mqb.4. human.

Organism-specific databases

CTDi78992.
GeneCardsiYIPF2.
HGNCiHGNC:28476. YIPF2.
HPAiHPA019902.
neXtProtiNX_Q9BWQ6.
PharmGKBiPA142670556.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3114. Eukaryota.
ENOG4110TJR. LUCA.
GeneTreeiENSGT00390000010157.
HOGENOMiHOG000231137.
HOVERGENiHBG056746.
InParanoidiQ9BWQ6.
OMAiRERAGPY.
OrthoDBiEOG091G0JY5.
PhylomeDBiQ9BWQ6.

Miscellaneous databases

ChiTaRSiYIPF2. human.
GenomeRNAii78992.
PROiQ9BWQ6.

Gene expression databases

BgeeiENSG00000130733.
CleanExiHS_YIPF2.
ExpressionAtlasiQ9BWQ6. baseline and differential.
GenevisibleiQ9BWQ6. HS.

Family and domain databases

InterProiIPR006977. Yip1.
[Graphical view]
PfamiPF04893. Yip1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYIPF2_HUMAN
AccessioniPrimary (citable) accession number: Q9BWQ6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.