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Q9BWN1

- PRR14_HUMAN

UniProt

Q9BWN1 - PRR14_HUMAN

Protein

Proline-rich protein 14

Gene

PRR14

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proline-rich protein 14
    Gene namesi
    Name:PRR14
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 16

    Organism-specific databases

    HGNCiHGNC:28458. PRR14.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA144596393.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 585585Proline-rich protein 14PRO_0000307269Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionine1 Publication

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ9BWN1.
    PaxDbiQ9BWN1.
    PRIDEiQ9BWN1.

    PTM databases

    PhosphoSiteiQ9BWN1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9BWN1.
    BgeeiQ9BWN1.
    CleanExiHS_PRR14.
    GenevestigatoriQ9BWN1.

    Organism-specific databases

    HPAiHPA052022.
    HPA060265.

    Interactioni

    Protein-protein interaction databases

    BioGridi122465. 10 interactions.
    IntActiQ9BWN1. 3 interactions.
    MINTiMINT-1482192.
    STRINGi9606.ENSP00000300835.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9BWN1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi85 – 378294Pro-richAdd
    BLAST

    Phylogenomic databases

    eggNOGiNOG29228.
    HOGENOMiHOG000115715.
    HOVERGENiHBG095164.
    InParanoidiQ9BWN1.
    OMAiEMARAPP.
    OrthoDBiEOG7ZPNMP.
    PhylomeDBiQ9BWN1.
    TreeFamiTF328446.

    Family and domain databases

    InterProiIPR026320. PRR14.
    IPR028149. Tantalus-like.
    [Graphical view]
    PANTHERiPTHR14522. PTHR14522. 1 hit.
    PfamiPF15386. Tantalus. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9BWN1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLPGDSSPP GQPRLCRQPL TRALWGARSP KRPRLQLPGA PSPLEKASRR    50
    VLAVVLEDVM AVHMVPVVPS KQTSIPQHHS YHQDPVHRQP PASPPRQAGW 100
    SSQARPPDPL CLCREPLSRI HRTSSTLRRR SRTTPGPEEG PSQKVDRAPQ 150
    PTLVVMLEDI ASPRPPAEGF IDETPNFIIP AQRAEPMRIV RQPTPPPGDL 200
    EPPFQPSALP ADPLESPPTA PDPALELPST PPPSSLLRPR LSPWGLAPLF 250
    RSVRSKLESF ADIFLTPNKT PQPPPPSPPM KLELKIAISE AEQSGAAEGT 300
    ASVSPRPPIR QWRTQDHNTP ALLPKPSLGR SYSCPDLGPP GPGTCTWPPA 350
    PPQPSRPRPR RHTVGGGEMA RAPPPPRPCL RKEVFPLGGV GASPSLTTSC 400
    SSTASTSFSE PAEPRLGSTK GKEPRASKDQ VLSEPETKTM GKVSRFRIRR 450
    TPARPQLNLT PMGLPRPIRL NKKEFSLEEI YTNKNYQSPT TRRTFETIFE 500
    EPRERNGTLI FTSSRKLRRA VEFRDSSLPR SRRPSRGVRA AGGRTVPPNV 550
    APSPDVGPLL QQRLEELDAL LLEEETVDRE QPHWT 585
    Length:585
    Mass (Da):64,328
    Last modified:June 1, 2001 - v1
    Checksum:iEE706853CE2D2742
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti359 – 3591P → L.1 Publication
    Corresponds to variant rs3747481 [ dbSNP | Ensembl ].
    VAR_035389

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK074783 mRNA. Translation: BAC11207.1.
    CH471192 Genomic DNA. Translation: EAW52222.1.
    BC000119 mRNA. Translation: AAH00119.1.
    BC021934 mRNA. Translation: AAH21934.1.
    BC050677 mRNA. Translation: AAH50677.1.
    CCDSiCCDS10687.1.
    RefSeqiNP_076936.1. NM_024031.2.
    XP_005255623.1. XM_005255566.1.
    UniGeneiHs.293629.

    Genome annotation databases

    EnsembliENST00000300835; ENSP00000300835; ENSG00000156858.
    ENST00000542965; ENSP00000441641; ENSG00000156858.
    GeneIDi78994.
    KEGGihsa:78994.
    UCSCiuc002dyy.3. human.

    Polymorphism databases

    DMDMi74733447.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK074783 mRNA. Translation: BAC11207.1 .
    CH471192 Genomic DNA. Translation: EAW52222.1 .
    BC000119 mRNA. Translation: AAH00119.1 .
    BC021934 mRNA. Translation: AAH21934.1 .
    BC050677 mRNA. Translation: AAH50677.1 .
    CCDSi CCDS10687.1.
    RefSeqi NP_076936.1. NM_024031.2.
    XP_005255623.1. XM_005255566.1.
    UniGenei Hs.293629.

    3D structure databases

    ProteinModelPortali Q9BWN1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122465. 10 interactions.
    IntActi Q9BWN1. 3 interactions.
    MINTi MINT-1482192.
    STRINGi 9606.ENSP00000300835.

    PTM databases

    PhosphoSitei Q9BWN1.

    Polymorphism databases

    DMDMi 74733447.

    Proteomic databases

    MaxQBi Q9BWN1.
    PaxDbi Q9BWN1.
    PRIDEi Q9BWN1.

    Protocols and materials databases

    DNASUi 78994.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000300835 ; ENSP00000300835 ; ENSG00000156858 .
    ENST00000542965 ; ENSP00000441641 ; ENSG00000156858 .
    GeneIDi 78994.
    KEGGi hsa:78994.
    UCSCi uc002dyy.3. human.

    Organism-specific databases

    CTDi 78994.
    GeneCardsi GC16P030662.
    H-InvDB HIX0012967.
    HIX0079777.
    HGNCi HGNC:28458. PRR14.
    HPAi HPA052022.
    HPA060265.
    neXtProti NX_Q9BWN1.
    PharmGKBi PA144596393.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG29228.
    HOGENOMi HOG000115715.
    HOVERGENi HBG095164.
    InParanoidi Q9BWN1.
    OMAi EMARAPP.
    OrthoDBi EOG7ZPNMP.
    PhylomeDBi Q9BWN1.
    TreeFami TF328446.

    Miscellaneous databases

    ChiTaRSi PRR14. human.
    GenomeRNAii 78994.
    NextBioi 67587.
    PROi Q9BWN1.

    Gene expression databases

    ArrayExpressi Q9BWN1.
    Bgeei Q9BWN1.
    CleanExi HS_PRR14.
    Genevestigatori Q9BWN1.

    Family and domain databases

    InterProi IPR026320. PRR14.
    IPR028149. Tantalus-like.
    [Graphical view ]
    PANTHERi PTHR14522. PTHR14522. 1 hit.
    Pfami PF15386. Tantalus. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT LEU-359.
      Tissue: Eye and Pancreas.
    4. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiPRR14_HUMAN
    AccessioniPrimary (citable) accession number: Q9BWN1
    Secondary accession number(s): Q8WTX2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 23, 2007
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 16
      Human chromosome 16: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3