Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9BWN1 (PRR14_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proline-rich protein 14
Gene names
Name:PRR14
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Coding sequence diversityPolymorphism
   PTMAcetylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Proline-rich protein 14
PRO_0000307269

Regions

Compositional bias85 – 378294Pro-rich

Amino acid modifications

Modified residue11N-acetylmethionine Ref.4

Natural variations

Natural variant3591P → L. Ref.3
Corresponds to variant rs3747481 [ dbSNP | Ensembl ].
VAR_035389

Sequences

Sequence LengthMass (Da)Tools
Q9BWN1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: EE706853CE2D2742

FASTA58564,328
        10         20         30         40         50         60 
MDLPGDSSPP GQPRLCRQPL TRALWGARSP KRPRLQLPGA PSPLEKASRR VLAVVLEDVM 

        70         80         90        100        110        120 
AVHMVPVVPS KQTSIPQHHS YHQDPVHRQP PASPPRQAGW SSQARPPDPL CLCREPLSRI 

       130        140        150        160        170        180 
HRTSSTLRRR SRTTPGPEEG PSQKVDRAPQ PTLVVMLEDI ASPRPPAEGF IDETPNFIIP 

       190        200        210        220        230        240 
AQRAEPMRIV RQPTPPPGDL EPPFQPSALP ADPLESPPTA PDPALELPST PPPSSLLRPR 

       250        260        270        280        290        300 
LSPWGLAPLF RSVRSKLESF ADIFLTPNKT PQPPPPSPPM KLELKIAISE AEQSGAAEGT 

       310        320        330        340        350        360 
ASVSPRPPIR QWRTQDHNTP ALLPKPSLGR SYSCPDLGPP GPGTCTWPPA PPQPSRPRPR 

       370        380        390        400        410        420 
RHTVGGGEMA RAPPPPRPCL RKEVFPLGGV GASPSLTTSC SSTASTSFSE PAEPRLGSTK 

       430        440        450        460        470        480 
GKEPRASKDQ VLSEPETKTM GKVSRFRIRR TPARPQLNLT PMGLPRPIRL NKKEFSLEEI 

       490        500        510        520        530        540 
YTNKNYQSPT TRRTFETIFE EPRERNGTLI FTSSRKLRRA VEFRDSSLPR SRRPSRGVRA 

       550        560        570        580 
AGGRTVPPNV APSPDVGPLL QQRLEELDAL LLEEETVDRE QPHWT 

« Hide

References

[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT LEU-359.
Tissue: Eye and Pancreas.
[4]"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK074783 mRNA. Translation: BAC11207.1.
CH471192 Genomic DNA. Translation: EAW52222.1.
BC000119 mRNA. Translation: AAH00119.1.
BC021934 mRNA. Translation: AAH21934.1.
BC050677 mRNA. Translation: AAH50677.1.
CCDSCCDS10687.1.
RefSeqNP_076936.1. NM_024031.2.
XP_005255623.1. XM_005255566.1.
UniGeneHs.293629.

3D structure databases

ProteinModelPortalQ9BWN1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid122465. 10 interactions.
IntActQ9BWN1. 3 interactions.
MINTMINT-1482192.
STRING9606.ENSP00000300835.

PTM databases

PhosphoSiteQ9BWN1.

Polymorphism databases

DMDM74733447.

Proteomic databases

MaxQBQ9BWN1.
PaxDbQ9BWN1.
PRIDEQ9BWN1.

Protocols and materials databases

DNASU78994.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000300835; ENSP00000300835; ENSG00000156858.
ENST00000542965; ENSP00000441641; ENSG00000156858.
GeneID78994.
KEGGhsa:78994.
UCSCuc002dyy.3. human.

Organism-specific databases

CTD78994.
GeneCardsGC16P030662.
H-InvDBHIX0012967.
HIX0079777.
HGNCHGNC:28458. PRR14.
HPAHPA052022.
HPA060265.
neXtProtNX_Q9BWN1.
PharmGKBPA144596393.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG29228.
HOGENOMHOG000115715.
HOVERGENHBG095164.
InParanoidQ9BWN1.
OMAEMARAPP.
OrthoDBEOG7ZPNMP.
PhylomeDBQ9BWN1.
TreeFamTF328446.

Gene expression databases

ArrayExpressQ9BWN1.
BgeeQ9BWN1.
CleanExHS_PRR14.
GenevestigatorQ9BWN1.

Family and domain databases

InterProIPR026320. PRR14.
IPR028149. Tantalus-like.
[Graphical view]
PANTHERPTHR14522. PTHR14522. 1 hit.
PfamPF15386. Tantalus. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSPRR14. human.
GenomeRNAi78994.
NextBio67587.
PROQ9BWN1.

Entry information

Entry namePRR14_HUMAN
AccessionPrimary (citable) accession number: Q9BWN1
Secondary accession number(s): Q8WTX2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM