Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9BWD3

- F127B_HUMAN

UniProt

Q9BWD3 - F127B_HUMAN

Protein

Protein FAM127B

Gene

FAM127B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein FAM127B
    Alternative name(s):
    Mammalian retrotransposon derived protein 8A
    Gene namesi
    Name:FAM127B
    Synonyms:CXX1B, MAR8A
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:24514. FAM127B.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162385915.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 113113Protein FAM127BPRO_0000311693Add
    BLAST

    Proteomic databases

    MaxQBiQ9BWD3.
    PaxDbiQ9BWD3.
    PRIDEiQ9BWD3.

    PTM databases

    PhosphoSiteiQ9BWD3.

    Expressioni

    Gene expression databases

    BgeeiQ9BWD3.
    CleanExiHS_FAM127B.
    GenevestigatoriQ9BWD3.

    Organism-specific databases

    HPAiHPA042173.

    Interactioni

    Protein-protein interaction databases

    BioGridi117530. 5 interactions.
    IntActiQ9BWD3. 1 interaction.
    STRINGi9606.ENSP00000375267.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9BWD3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FAM127 family.Curated

    Phylogenomic databases

    eggNOGiNOG294112.
    HOGENOMiHOG000049195.
    HOVERGENiHBG052318.
    InParanoidiQ9BWD3.
    OMAiLMAWPRR.
    OrthoDBiEOG722JBJ.
    PhylomeDBiQ9BWD3.
    TreeFamiTF337843.

    Sequencei

    Sequence statusi: Complete.

    Q9BWD3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDGRVQLMKA LLAGPLRPAA RRWRNPIPFP ETFDGDTDRL PEFIVQTSSY    50
    MFVDENTFSN DALKVTFLIT RLTGPALQWV IPYIRKESPL LNDYRGFLAE 100
    MKRVFGWEED EDF 113
    Length:113
    Mass (Da):13,188
    Last modified:December 4, 2007 - v3
    Checksum:i65227B6D28946B9F
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti48 – 481S → C.1 Publication
    Corresponds to variant rs2498776 [ dbSNP | Ensembl ].
    VAR_060162

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL136169 Genomic DNA. Translation: CAD92617.2.
    BC000393 mRNA. Translation: AAH00393.2.
    BC019300 mRNA. Translation: AAH19300.1.
    CCDSiCCDS43998.1.
    RefSeqiNP_001071640.1. NM_001078172.1.
    NP_001127793.1. NM_001134321.1.
    UniGeneiHs.460924.

    Genome annotation databases

    EnsembliENST00000370775; ENSP00000375267; ENSG00000203950.
    GeneIDi26071.
    KEGGihsa:26071.
    UCSCiuc004eyf.3. human.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL136169 Genomic DNA. Translation: CAD92617.2 .
    BC000393 mRNA. Translation: AAH00393.2 .
    BC019300 mRNA. Translation: AAH19300.1 .
    CCDSi CCDS43998.1.
    RefSeqi NP_001071640.1. NM_001078172.1.
    NP_001127793.1. NM_001134321.1.
    UniGenei Hs.460924.

    3D structure databases

    ProteinModelPortali Q9BWD3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 117530. 5 interactions.
    IntActi Q9BWD3. 1 interaction.
    STRINGi 9606.ENSP00000375267.

    PTM databases

    PhosphoSitei Q9BWD3.

    Proteomic databases

    MaxQBi Q9BWD3.
    PaxDbi Q9BWD3.
    PRIDEi Q9BWD3.

    Protocols and materials databases

    DNASUi 26071.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000370775 ; ENSP00000375267 ; ENSG00000203950 .
    GeneIDi 26071.
    KEGGi hsa:26071.
    UCSCi uc004eyf.3. human.

    Organism-specific databases

    CTDi 26071.
    GeneCardsi GC0XM134184.
    H-InvDB HIX0014311.
    HGNCi HGNC:24514. FAM127B.
    HPAi HPA042173.
    neXtProti NX_Q9BWD3.
    PharmGKBi PA162385915.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG294112.
    HOGENOMi HOG000049195.
    HOVERGENi HBG052318.
    InParanoidi Q9BWD3.
    OMAi LMAWPRR.
    OrthoDBi EOG722JBJ.
    PhylomeDBi Q9BWD3.
    TreeFami TF337843.

    Miscellaneous databases

    ChiTaRSi FAM127B. human.
    GenomeRNAii 26071.
    NextBioi 47979.
    PROi Q9BWD3.

    Gene expression databases

    Bgeei Q9BWD3.
    CleanExi HS_FAM127B.
    Genevestigatori Q9BWD3.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT CYS-48.
      Tissue: Lung.
    3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiF127B_HUMAN
    AccessioniPrimary (citable) accession number: Q9BWD3
    Secondary accession number(s): A2A2V9, Q8TBU2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 4, 2007
    Last sequence update: December 4, 2007
    Last modified: October 1, 2014
    This is version 78 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3