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Q9BWD3

- F127B_HUMAN

UniProt

Q9BWD3 - F127B_HUMAN

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Protein

Protein FAM127B

Gene

FAM127B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM127B
Alternative name(s):
Mammalian retrotransposon derived protein 8A
Gene namesi
Name:FAM127B
Synonyms:CXX1B, MAR8A
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:24514. FAM127B.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162385915.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 113113Protein FAM127BPRO_0000311693Add
BLAST

Proteomic databases

MaxQBiQ9BWD3.
PaxDbiQ9BWD3.
PRIDEiQ9BWD3.

PTM databases

PhosphoSiteiQ9BWD3.

Expressioni

Gene expression databases

BgeeiQ9BWD3.
CleanExiHS_FAM127B.
GenevestigatoriQ9BWD3.

Organism-specific databases

HPAiHPA042173.

Interactioni

Protein-protein interaction databases

BioGridi117530. 6 interactions.
IntActiQ9BWD3. 1 interaction.
STRINGi9606.ENSP00000375267.

Structurei

3D structure databases

ProteinModelPortaliQ9BWD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM127 family.Curated

Phylogenomic databases

eggNOGiNOG294112.
GeneTreeiENSGT00510000047956.
HOGENOMiHOG000049195.
HOVERGENiHBG052318.
InParanoidiQ9BWD3.
OMAiLMAWPRR.
OrthoDBiEOG722JBJ.
PhylomeDBiQ9BWD3.
TreeFamiTF337843.

Sequencei

Sequence statusi: Complete.

Q9BWD3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDGRVQLMKA LLAGPLRPAA RRWRNPIPFP ETFDGDTDRL PEFIVQTSSY
60 70 80 90 100
MFVDENTFSN DALKVTFLIT RLTGPALQWV IPYIRKESPL LNDYRGFLAE
110
MKRVFGWEED EDF
Length:113
Mass (Da):13,188
Last modified:December 4, 2007 - v3
Checksum:i65227B6D28946B9F
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti48 – 481S → C.1 Publication
Corresponds to variant rs2498776 [ dbSNP | Ensembl ].
VAR_060162

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136169 Genomic DNA. Translation: CAD92617.2.
BC000393 mRNA. Translation: AAH00393.2.
BC019300 mRNA. Translation: AAH19300.1.
CCDSiCCDS43998.1.
RefSeqiNP_001071640.1. NM_001078172.1.
NP_001127793.1. NM_001134321.1.
UniGeneiHs.460924.

Genome annotation databases

EnsembliENST00000370775; ENSP00000375267; ENSG00000203950.
GeneIDi26071.
KEGGihsa:26071.
UCSCiuc004eyf.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136169 Genomic DNA. Translation: CAD92617.2 .
BC000393 mRNA. Translation: AAH00393.2 .
BC019300 mRNA. Translation: AAH19300.1 .
CCDSi CCDS43998.1.
RefSeqi NP_001071640.1. NM_001078172.1.
NP_001127793.1. NM_001134321.1.
UniGenei Hs.460924.

3D structure databases

ProteinModelPortali Q9BWD3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 117530. 6 interactions.
IntActi Q9BWD3. 1 interaction.
STRINGi 9606.ENSP00000375267.

PTM databases

PhosphoSitei Q9BWD3.

Proteomic databases

MaxQBi Q9BWD3.
PaxDbi Q9BWD3.
PRIDEi Q9BWD3.

Protocols and materials databases

DNASUi 26071.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000370775 ; ENSP00000375267 ; ENSG00000203950 .
GeneIDi 26071.
KEGGi hsa:26071.
UCSCi uc004eyf.3. human.

Organism-specific databases

CTDi 26071.
GeneCardsi GC0XM134184.
H-InvDB HIX0014311.
HGNCi HGNC:24514. FAM127B.
HPAi HPA042173.
neXtProti NX_Q9BWD3.
PharmGKBi PA162385915.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG294112.
GeneTreei ENSGT00510000047956.
HOGENOMi HOG000049195.
HOVERGENi HBG052318.
InParanoidi Q9BWD3.
OMAi LMAWPRR.
OrthoDBi EOG722JBJ.
PhylomeDBi Q9BWD3.
TreeFami TF337843.

Miscellaneous databases

ChiTaRSi FAM127B. human.
GenomeRNAii 26071.
NextBioi 47979.
PROi Q9BWD3.

Gene expression databases

Bgeei Q9BWD3.
CleanExi HS_FAM127B.
Genevestigatori Q9BWD3.

Family and domain databases

ProtoNeti Search...

Publicationsi

  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT CYS-48.
    Tissue: Lung.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiF127B_HUMAN
AccessioniPrimary (citable) accession number: Q9BWD3
Secondary accession number(s): A2A2V9, Q8TBU2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: December 4, 2007
Last modified: October 29, 2014
This is version 79 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3