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Protein

Coiled-coil domain-containing protein 94

Gene

CCDC94

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 94
Gene namesi
Name:CCDC94
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000105248.15
HGNCiHGNC:25518 CCDC94
neXtProtiNX_Q9BW85

Pathology & Biotechi

Organism-specific databases

DisGeNETi55702
OpenTargetsiENSG00000105248
PharmGKBiPA144596461

Polymorphism and mutation databases

BioMutaiCCDC94
DMDMi74733407

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002340181 – 323Coiled-coil domain-containing protein 94Add BLAST323

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei211PhosphoserineCombined sources1
Modified residuei213PhosphoserineCombined sources1
Modified residuei220PhosphoserineCombined sources1
Modified residuei316PhosphoserineBy similarity1
Modified residuei319PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9BW85
MaxQBiQ9BW85
PaxDbiQ9BW85
PeptideAtlasiQ9BW85
PRIDEiQ9BW85
ProteomicsDBi79263

PTM databases

iPTMnetiQ9BW85
PhosphoSitePlusiQ9BW85

Expressioni

Gene expression databases

BgeeiENSG00000105248
CleanExiHS_CCDC94
ExpressionAtlasiQ9BW85 baseline and differential
GenevisibleiQ9BW85 HS

Organism-specific databases

HPAiHPA043606
HPA055675

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi120827, 40 interactors
IntActiQ9BW85, 27 interactors
MINTiQ9BW85
STRINGi9606.ENSP00000262962

Structurei

3D structure databases

ProteinModelPortaliQ9BW85
SMRiQ9BW85
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili105 – 206Sequence analysisAdd BLAST102

Sequence similaritiesi

Belongs to the CWC16 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG2989 Eukaryota
COG5134 LUCA
GeneTreeiENSGT00530000063615
HOGENOMiHOG000160812
HOVERGENiHBG053135
InParanoidiQ9BW85
OMAiNTDYAME
OrthoDBiEOG091G0JDG
PhylomeDBiQ9BW85
TreeFamiTF315070

Family and domain databases

InterProiView protein in InterPro
IPR007590 CWC16
PANTHERiPTHR12111 PTHR12111, 1 hit
PfamiView protein in Pfam
PF04502 DUF572, 1 hit

Sequencei

Sequence statusi: Complete.

Q9BW85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSERKVLNKY YPPDFDPSKI PKLKLPKDRQ YVVRLMAPFN MRCKTCGEYI
60 70 80 90 100
YKGKKFNARK ETVQNEVYLG LPIFRFYIKC TRCLAEITFK TDPENTDYTM
110 120 130 140 150
EHGATRNFQA EKLLEEEEKR VQKEREDEEL NNPMKVLENR TKDSKLEMEV
160 170 180 190 200
LENLQELKDL NQRQAHVDFE AMLRQHRLSE EERRRQQQEE DEQETAALLE
210 220 230 240 250
EARKRRLLED SDSEDEAAPS PLQPALRPNP TAILDEAPKP KRKVEVWEQS
260 270 280 290 300
VGSLGSRPPL SRLVVVKKAK ADPDCSNGQP QAAPTPGAPQ NRKEANPTPL
310 320
TPGASSLSQL GAYLDSDDSN GSN
Length:323
Mass (Da):37,086
Last modified:June 1, 2001 - v1
Checksum:i8E1BB92C4A008BB5
GO

Sequence cautioni

The sequence AAC72949 differs from that shown. Reason: Frameshift at position 285.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti105T → A in BAA91572 (PubMed:14702039).Curated1
Sequence conflicti247W → R in BAB14757 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001236 mRNA Translation: BAA91572.1
AK023988 mRNA Translation: BAB14757.1
AF091080 mRNA Translation: AAC72949.1 Frameshift.
BC000561 mRNA Translation: AAH00561.1
BC019096 mRNA Translation: AAH19096.1
CCDSiCCDS12124.1
RefSeqiNP_060544.2, NM_018074.5
UniGeneiHs.21811

Genome annotation databases

EnsembliENST00000262962; ENSP00000262962; ENSG00000105248
GeneIDi55702
KEGGihsa:55702
UCSCiuc002lzv.5 human

Similar proteinsi

Entry informationi

Entry nameiCCD94_HUMAN
AccessioniPrimary (citable) accession number: Q9BW85
Secondary accession number(s): O75270, Q9H862, Q9NW16
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: June 1, 2001
Last modified: June 20, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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